STAR and CCHCR1

Number of citations of the paper that reports this interaction (PMID 12909641)
4

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		STAR	CCHCR1
Gene Name		steroidogenic acute regulatory protein	coiled-coil alpha-helical rod protein 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrial Intermembrane Space Cytosol Mitochondrial Crista Neuron Projection Neuronal Cell Body	Nucleus Cytoplasm Centriole
	Molecular Function	Cholesterol Binding Cholesterol Transporter Activity
	Biological Process	Steroid Biosynthetic Process Bile Acid Biosynthetic Process C21-steroid Hormone Biosynthetic Process Progesterone Biosynthetic Process Estrogen Biosynthetic Process Brain Development Response To Nutrient Steroid Metabolic Process Cholesterol Metabolic Process Glucocorticoid Metabolic Process Male Gonad Development Response To Herbicide Response To Ionizing Radiation Response To Lead Ion Positive Regulation Of Gene Expression Response To Activity Diterpenoid Metabolic Process Insecticide Metabolic Process Biphenyl Metabolic Process Dibenzo-p-dioxin Metabolic Process Phenol-containing Compound Metabolic Process Phthalate Metabolic Process Intracellular Cholesterol Transport Cellular Response To Insulin Stimulus Response To Nicotine Cellular Response To Interferon-alpha Response To Drug Response To Hydrogen Peroxide Circadian Sleep/wake Cycle, REM Sleep Negative Regulation Of Neuron Apoptotic Process Response To Estrogen Small Molecule Metabolic Process Response To Leptin Cellular Response To Fibroblast Growth Factor Stimulus Response To Ethanol Regulation Of Neuronal Synaptic Plasticity Fractalkine Metabolic Process Positive Regulation Of Neurogenesis Regulation Of Steroid Biosynthetic Process Response To Corticosterone Response To Fungicide Testosterone Biosynthetic Process Cellular Response To Lipopolysaccharide Cellular Response To Antibiotic Cellular Response To Cadmium Ion Cellular Response To Alkaloid Cellular Response To CAMP Cellular Response To Glucose Stimulus Cellular Response To Interferon-gamma Cellular Response To Follicle-stimulating Hormone Stimulus Cellular Response To Luteinizing Hormone Stimulus Cellular Response To Growth Hormone Stimulus Cellular Response To Dexamethasone Stimulus Cellular Response To Transforming Growth Factor Beta Stimulus Cellular Response To Epinephrine Stimulus	Protein Export From Nucleus Multicellular Organismal Development Cell Differentiation
Pathways		Metabolism of lipids and lipoproteins Pregnenolone biosynthesis Metabolism of steroid hormones and vitamin D
Drugs
Diseases
GWAS			Chronic obstructive pulmonary disease-related biomarkers ( 23144326) Hematology traits ( 23263863) Nevirapine-induced rash ( 21810746) Prostate cancer ( 21743467) Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS-TEN) ( 21912425) White blood cell count ( 21738480)
Protein-Protein Interactions		6 interactors: CCHCR1 FEZ1 LIPE MAGEA11 MAPK3 NUCB2	57 interactors: ABI2 ALAS1 AMOTL2 ATG5 BLOC1S6 C1orf94 CARD9 CCDC102B CCDC136 CCDC53 CDR2 CEP55 CTAGE5 DTNBP1 EFHC2 FSD2 GOLGA2 HAUS1 HSBP1 IKBKG KRT13 KRT15 KRT31 KRT40 MAD1L1 MED4 MID2 MTUS2 NAB2 NDC80 NDEL1 NINL NME7 NUP62 NUTM1 PIAS2 POLD2 POLR2C PRKCG RBM17 SAT1 SPAG5 SSX2IP STAR TADA2A TEKT1 TFIP11 TPM3 TRAF1 TRAF2 TRAF4 TRIM27 TSGA10 TXLNA TXLNB USHBP1 ZFYVE19
Entrez ID		6770	54535
HPRD ID		02794	05607
Ensembl ID			ENSG00000204536
Uniprot IDs		P49675 Q6IBK0	B0S7V6 D2IYK9 M1T2K8 M1TIV4 Q2TB68 Q769H0 Q8TD31
PDB IDs		1IMG 2I93 3P0L
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Apolipoprotein Binding Diacylglycerol Catabolic Process Regulation Of Golgi Inheritance Caveolin-mediated Endocytosis Positive Regulation Of Histone Phosphorylation Long-chain Fatty Acid Catabolic Process Regulation Of Golgi Organization Axon Guidance Regulation Of Early Endosome To Late Endosome Transport DNA Damage Induced Protein Phosphorylation Negative Regulation Of Macroautophagy Establishment Of Mitochondrion Localization Diacylglycerol Metabolic Process Axonogenesis Interleukin-1-mediated Signaling Pathway Axon Development Cellular Response To Growth Factor Stimulus Triglyceride Catabolic Process Cell Morphogenesis Involved In Neuron Differentiation Positive Regulation Of Histone Acetylation Response To Growth Factor Chemotaxis JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Acylglycerol Catabolic Process Positive Regulation Of Peptidyl-lysine Acetylation Growth Hormone Receptor Signaling Pathway Neuron Projection Morphogenesis Positive Regulation Of Protein Acetylation Cellular Response To Growth Hormone Stimulus Transcription Initiation From RNA Polymerase I Promoter Response To Epidermal Growth Factor Regulation Of Cellular Response To Heat Protein Export From Nucleus Cell Morphogenesis Involved In Differentiation Transcription From RNA Polymerase I Promoter Negative Regulation Of Autophagy Mitochondrion Localization Lipopolysaccharide-mediated Signaling Pathway Peptidyl-tyrosine Autophosphorylation Response To Growth Hormone Neuron Projection Development	Mitotic Cell Cycle Mitotic Cell Cycle Process Microtubule-based Transport Activation Of NF-kappaB-inducing Kinase Activity Cytoskeleton-dependent Intracellular Transport Organelle Organization Positive Regulation Of NIK/NF-kappaB Signaling Cell Cycle Process NIK/NF-kappaB Signaling Mitotic Nuclear Division Cell Cycle Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Microtubule-based Process Positive Regulation Of NF-kappaB Transcription Factor Activity Axon Cargo Transport Innate Immune Response Cell Division Positive Regulation Of Protein Homodimerization Activity Cytoskeleton Organization Microtubule-based Movement Establishment Of Organelle Localization Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Viral Transcription Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Viral Release From Host Cell Establishment Of Vesicle Localization Intracellular Receptor Signaling Pathway Anterograde Synaptic Vesicle Transport Negative Regulation Of Neuron Death Vesicle Localization Regulation Of Protein Homodimerization Activity Centrosome Organization Negative Regulation Of Viral Transcription Melanosome Organization Establishment Of Localization In Cell Pigment Granule Organization Regulation Of Viral Release From Host Cell Regulation Of I-kappaB Kinase/NF-kappaB Signaling Developmental Process Organelle Localization Microtubule Organizing Center Organization Cellular Localization Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Anterograde Axon Cargo Transport Regulation Of Apoptotic Process Microtubule Cytoskeleton Organization Positive Regulation Of JNK Cascade Spindle Organization Regulation Of Cell Death
Tagcloud ?		22r availability cholesterol cytochrome cytokine derivative exerted hcg hydroxycholesterol incubated leydig lh linking maximal membranes messenger mitochondria ng nm observation p450scc p55 passes porcine readily steroidogenic testicular testosterone tnfalpha
Tagcloud (Difference) ?		22r availability cholesterol cytochrome cytokine derivative exerted hcg hydroxycholesterol incubated leydig lh linking maximal membranes messenger mitochondria ng nm observation p450scc p55 passes porcine readily steroidogenic testicular testosterone tnfalpha
Tagcloud (Intersection) ?