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STAR

Description steroidogenic acute regulatory protein
Image
GO Annotations Cellular Component
  • Mitochondrion
  • Mitochondrial Intermembrane Space
  • Mitochondrial Matrix
Molecular Function
  • Protein Binding
  • Lipid Binding
  • Cholesterol Binding
  • Cholesterol Transfer Activity
Biological Process
  • Lipid Metabolic Process
  • Steroid Biosynthetic Process
  • Lipid Transport
  • Cholesterol Metabolic Process
  • Glucocorticoid Metabolic Process
  • Intracellular Cholesterol Transport
  • Regulation Of Steroid Biosynthetic Process
  • Positive Regulation Of Bile Acid Biosynthetic Process
Pathways
  • Pregnenolone biosynthesis
  • Mitochondrial protein degradation
Drugs
Diseases
  • Congenital adrenal hyperplasia (CAH)
  • 46,XY disorders of sex development (Disorders in androgen synthesis or action), including: Congenital adrenal hyperplasias; Leydig cell hypoplasia; Androgen insensitivity syndrome (AIS)
GWAS
  • Menopause (age at onset) ( 26414677)
  • Orthostatic hypotension ( 24124408)
  • Schizophrenia ( 29483656)
Interacting Genes 12 interacting genes: AGTRAP CCHCR1 CMTM4 DGAT2L6 FEZ1 LIPE MAGEA11 MAPK3 NUCB2 RABEP1 SMPD2 STX8
Entrez ID 6770
HPRD ID 02794
Ensembl ID ENSG00000147465
Uniprot IDs P49675 Q6IBK0
PDB IDs 3P0L 5OMA 6T5F 6T5H
Enriched GO Terms of Interacting Partners?
  • Caveola
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© Madhavi K. Ganapathiraju 2012-2025