STAR and LIPE

Number of citations of the paper that reports this interaction (PMID 12925534)
16

Data Source:
HPRD (in vivo, in vitro)

		STAR	LIPE
Gene Name		steroidogenic acute regulatory protein	lipase, hormone-sensitive
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrial Intermembrane Space Cytosol Mitochondrial Crista Neuron Projection Neuronal Cell Body	Lipid Particle Cytosol Caveola
	Molecular Function	Cholesterol Binding Cholesterol Transporter Activity	Triglyceride Lipase Activity Protein Binding Protein Kinase Binding Hormone-sensitive Lipase Activity
	Biological Process	Steroid Biosynthetic Process Bile Acid Biosynthetic Process C21-steroid Hormone Biosynthetic Process Progesterone Biosynthetic Process Estrogen Biosynthetic Process Brain Development Response To Nutrient Steroid Metabolic Process Cholesterol Metabolic Process Glucocorticoid Metabolic Process Male Gonad Development Response To Herbicide Response To Ionizing Radiation Response To Lead Ion Positive Regulation Of Gene Expression Response To Activity Diterpenoid Metabolic Process Insecticide Metabolic Process Biphenyl Metabolic Process Dibenzo-p-dioxin Metabolic Process Phenol-containing Compound Metabolic Process Phthalate Metabolic Process Intracellular Cholesterol Transport Cellular Response To Insulin Stimulus Response To Nicotine Cellular Response To Interferon-alpha Response To Drug Response To Hydrogen Peroxide Circadian Sleep/wake Cycle, REM Sleep Negative Regulation Of Neuron Apoptotic Process Response To Estrogen Small Molecule Metabolic Process Response To Leptin Cellular Response To Fibroblast Growth Factor Stimulus Response To Ethanol Regulation Of Neuronal Synaptic Plasticity Fractalkine Metabolic Process Positive Regulation Of Neurogenesis Regulation Of Steroid Biosynthetic Process Response To Corticosterone Response To Fungicide Testosterone Biosynthetic Process Cellular Response To Lipopolysaccharide Cellular Response To Antibiotic Cellular Response To Cadmium Ion Cellular Response To Alkaloid Cellular Response To CAMP Cellular Response To Glucose Stimulus Cellular Response To Interferon-gamma Cellular Response To Follicle-stimulating Hormone Stimulus Cellular Response To Luteinizing Hormone Stimulus Cellular Response To Growth Hormone Stimulus Cellular Response To Dexamethasone Stimulus Cellular Response To Transforming Growth Factor Beta Stimulus Cellular Response To Epinephrine Stimulus	Protein Phosphorylation Cholesterol Metabolic Process Lipid Catabolic Process Triglyceride Catabolic Process Long-chain Fatty Acid Catabolic Process Small Molecule Metabolic Process Diacylglycerol Catabolic Process
Pathways		Metabolism of lipids and lipoproteins Pregnenolone biosynthesis Metabolism of steroid hormones and vitamin D	Metabolism of lipids and lipoproteins Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis Lipid digestion, mobilization, and transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: CCHCR1 FEZ1 LIPE MAGEA11 MAPK3 NUCB2	8 interactors: FABP4 KATNA1 MAPK1 MAPK3 NSFL1C PLIN1 PRKACA STAR
Entrez ID		6770	3991
HPRD ID		02794	01062
Ensembl ID			ENSG00000079435
Uniprot IDs		P49675 Q6IBK0	Q05469
PDB IDs		1IMG 2I93 3P0L
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Apolipoprotein Binding Diacylglycerol Catabolic Process Regulation Of Golgi Inheritance Caveolin-mediated Endocytosis Positive Regulation Of Histone Phosphorylation Long-chain Fatty Acid Catabolic Process Regulation Of Golgi Organization Axon Guidance Regulation Of Early Endosome To Late Endosome Transport DNA Damage Induced Protein Phosphorylation Negative Regulation Of Macroautophagy Establishment Of Mitochondrion Localization Diacylglycerol Metabolic Process Axonogenesis Interleukin-1-mediated Signaling Pathway Axon Development Cellular Response To Growth Factor Stimulus Triglyceride Catabolic Process Cell Morphogenesis Involved In Neuron Differentiation Positive Regulation Of Histone Acetylation Response To Growth Factor Chemotaxis JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Acylglycerol Catabolic Process Positive Regulation Of Peptidyl-lysine Acetylation Growth Hormone Receptor Signaling Pathway Neuron Projection Morphogenesis Positive Regulation Of Protein Acetylation Cellular Response To Growth Hormone Stimulus Transcription Initiation From RNA Polymerase I Promoter Response To Epidermal Growth Factor Regulation Of Cellular Response To Heat Protein Export From Nucleus Cell Morphogenesis Involved In Differentiation Transcription From RNA Polymerase I Promoter Negative Regulation Of Autophagy Mitochondrion Localization Lipopolysaccharide-mediated Signaling Pathway Peptidyl-tyrosine Autophosphorylation Response To Growth Hormone Neuron Projection Development	Triglyceride Catabolic Process Cellular Response To Growth Hormone Stimulus Acylglycerol Catabolic Process Response To Growth Hormone Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Regulation Of Golgi Inheritance Caveolin-mediated Endocytosis Cellular Response To Peptide Hormone Stimulus Regulation Of Golgi Organization Cellular Response To Peptide Triglyceride Metabolic Process Vascular Endothelial Growth Factor Receptor Signaling Pathway Neutral Lipid Metabolic Process Regulation Of Early Endosome To Late Endosome Transport Response To Peptide Hormone Cellular Response To Organonitrogen Compound Response To Peptide Cellular Response To Epinephrine Stimulus Cellular Lipid Catabolic Process Cellular Response To Lipopolysaccharide Response To Epinephrine Cellular Response To Molecule Of Bacterial Origin Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cellular Response To Growth Factor Stimulus Cellular Response To Hormone Stimulus JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Response To Growth Factor Platelet Activation Growth Hormone Receptor Signaling Pathway Cellular Response To Catecholamine Stimulus Neurotrophin TRK Receptor Signaling Pathway Cellular Response To Insulin Stimulus Response To Epidermal Growth Factor Regulation Of Cellular Response To Heat Neurotrophin Signaling Pathway Response To Cytokine Regulation Of Protein Kinase Activity Lipid Catabolic Process Lipopolysaccharide-mediated Signaling Pathway Regulation Of Kinase Activity Activation Of Protein Kinase Activity Innate Immune Response Response To Organonitrogen Compound Response To Insulin Regulation Of MAP Kinase Activity Peptidyl-threonine Phosphorylation Response To Exogenous DsRNA
Tagcloud ?		22r availability cholesterol cytochrome cytokine derivative exerted hcg hydroxycholesterol incubated leydig lh linking maximal membranes messenger mitochondria ng nm observation p450scc p55 passes porcine readily steroidogenic testicular testosterone tnfalpha	abhd5 agpat2 anomaly atgl cgi ctgm dgat1 diverge enteropathy gk glycerol gpd1 hsl ichthyosis inborn jordan lipodystrophy loosing lpin1 lpin2 majeed nlsd perilipin pnpla2 pseudohypertriglyceridemia rhabdomyolysis steatosis tgs vacuolated
Tagcloud (Difference) ?		22r availability cholesterol cytochrome cytokine derivative exerted hcg hydroxycholesterol incubated leydig lh linking maximal membranes messenger mitochondria ng nm observation p450scc p55 passes porcine readily steroidogenic testicular testosterone tnfalpha	abhd5 agpat2 anomaly atgl cgi ctgm dgat1 diverge enteropathy gk glycerol gpd1 hsl ichthyosis inborn jordan lipodystrophy loosing lpin1 lpin2 majeed nlsd perilipin pnpla2 pseudohypertriglyceridemia rhabdomyolysis steatosis tgs vacuolated
Tagcloud (Intersection) ?