STAR and FEZ1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		STAR	FEZ1
Gene Name		steroidogenic acute regulatory protein	fasciculation and elongation protein zeta 1 (zygin I)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrial Intermembrane Space Cytosol Mitochondrial Crista Neuron Projection Neuronal Cell Body	Cytoplasm Mitochondrion Centrosome Microtubule Plasma Membrane Microtubule Cytoskeleton Axon Dendrite
	Molecular Function	Cholesterol Binding Cholesterol Transporter Activity	Protein Kinase C Binding Protein Binding Gamma-tubulin Binding Protein N-terminus Binding
	Biological Process	Steroid Biosynthetic Process Bile Acid Biosynthetic Process C21-steroid Hormone Biosynthetic Process Progesterone Biosynthetic Process Estrogen Biosynthetic Process Brain Development Response To Nutrient Steroid Metabolic Process Cholesterol Metabolic Process Glucocorticoid Metabolic Process Male Gonad Development Response To Herbicide Response To Ionizing Radiation Response To Lead Ion Positive Regulation Of Gene Expression Response To Activity Diterpenoid Metabolic Process Insecticide Metabolic Process Biphenyl Metabolic Process Dibenzo-p-dioxin Metabolic Process Phenol-containing Compound Metabolic Process Phthalate Metabolic Process Intracellular Cholesterol Transport Cellular Response To Insulin Stimulus Response To Nicotine Cellular Response To Interferon-alpha Response To Drug Response To Hydrogen Peroxide Circadian Sleep/wake Cycle, REM Sleep Negative Regulation Of Neuron Apoptotic Process Response To Estrogen Small Molecule Metabolic Process Response To Leptin Cellular Response To Fibroblast Growth Factor Stimulus Response To Ethanol Regulation Of Neuronal Synaptic Plasticity Fractalkine Metabolic Process Positive Regulation Of Neurogenesis Regulation Of Steroid Biosynthetic Process Response To Corticosterone Response To Fungicide Testosterone Biosynthetic Process Cellular Response To Lipopolysaccharide Cellular Response To Antibiotic Cellular Response To Cadmium Ion Cellular Response To Alkaloid Cellular Response To CAMP Cellular Response To Glucose Stimulus Cellular Response To Interferon-gamma Cellular Response To Follicle-stimulating Hormone Stimulus Cellular Response To Luteinizing Hormone Stimulus Cellular Response To Growth Hormone Stimulus Cellular Response To Dexamethasone Stimulus Cellular Response To Transforming Growth Factor Beta Stimulus Cellular Response To Epinephrine Stimulus	Transport Cell Adhesion Nervous System Development Axon Guidance Positive Regulation Of Neuron Projection Development Establishment Of Mitochondrion Localization Cellular Response To Growth Factor Stimulus
Pathways		Metabolism of lipids and lipoproteins Pregnenolone biosynthesis Metabolism of steroid hormones and vitamin D
Drugs
Diseases
GWAS			Schizophrenia ( 22688191 23894747)
Protein-Protein Interactions		6 interactors: CCHCR1 FEZ1 LIPE MAGEA11 MAPK3 NUCB2	57 interactors: BARD1 BORA BRD1 C16orf59 C8orf33 CCL7 CIB1 CLASP2 COL9A2 CSTF2 DIS3L2 DISC1 DNAAF5 DRAP1 FEZ2 GEMIN7 GTF2F1 HAP1 HTATSF1 HTT IMMT KIAA1377 LRIF1 MEST NBR1 NDUFB9 NEK1 OLFML3 P4HB PAM16 PDCD7 PRKCZ PTH PTN PTPRS RAB3GAP1 RAB3GAP2 RAI14 RIF1 SAP30L SCOC SERPINH1 SMARCD1 SMC3 SMEK2 STAR TAC3 TAF1D TAF9 TBC1D25 TLK2 TOMM20 TTR TXNDC9 UBE4B WWC1 ZNF251
Entrez ID		6770	9638
HPRD ID		02794	09212
Ensembl ID			ENSG00000149557
Uniprot IDs		P49675 Q6IBK0	Q99689
PDB IDs		1IMG 2I93 3P0L
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Apolipoprotein Binding Diacylglycerol Catabolic Process Regulation Of Golgi Inheritance Caveolin-mediated Endocytosis Positive Regulation Of Histone Phosphorylation Long-chain Fatty Acid Catabolic Process Regulation Of Golgi Organization Axon Guidance Regulation Of Early Endosome To Late Endosome Transport DNA Damage Induced Protein Phosphorylation Negative Regulation Of Macroautophagy Establishment Of Mitochondrion Localization Diacylglycerol Metabolic Process Axonogenesis Interleukin-1-mediated Signaling Pathway Axon Development Cellular Response To Growth Factor Stimulus Triglyceride Catabolic Process Cell Morphogenesis Involved In Neuron Differentiation Positive Regulation Of Histone Acetylation Response To Growth Factor Chemotaxis JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Acylglycerol Catabolic Process Positive Regulation Of Peptidyl-lysine Acetylation Growth Hormone Receptor Signaling Pathway Neuron Projection Morphogenesis Positive Regulation Of Protein Acetylation Cellular Response To Growth Hormone Stimulus Transcription Initiation From RNA Polymerase I Promoter Response To Epidermal Growth Factor Regulation Of Cellular Response To Heat Protein Export From Nucleus Cell Morphogenesis Involved In Differentiation Transcription From RNA Polymerase I Promoter Negative Regulation Of Autophagy Mitochondrion Localization Lipopolysaccharide-mediated Signaling Pathway Peptidyl-tyrosine Autophosphorylation Response To Growth Hormone Neuron Projection Development	Positive Regulation Of Endoplasmic Reticulum Tubular Network Organization Organelle Organization Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Regulation Of Cellular Process Vesicle Transport Along Microtubule Cell Cycle Mitotic Cell Cycle Microtubule-based Process Microtubule Cytoskeleton Organization Regulation Of Metabolic Process Response To Radiation Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Heterocycle Metabolic Process Cellular Process Cellular Homeostasis Organelle Transport Along Microtubule Positive Regulation Of Metabolic Process Response To Ionizing Radiation Response To Stimulus Movement Of Cell Or Subcellular Component Cell Division Regulation Of Intracellular Signal Transduction Cell Cycle Process Regulation Of Synaptic Plasticity Nucleobase-containing Compound Metabolic Process Cellular Response To DNA Damage Stimulus Regulation Of Synaptic Transmission Regulation Of Microtubule-based Process Response To Abiotic Stimulus Cellular Nitrogen Compound Metabolic Process Establishment Or Maintenance Of Cell Polarity Cellular Metabolic Process Mitotic Nuclear Division Mitotic Cell Cycle Process Homeostatic Process Regulation Of Signal Transduction Regulation Of Signaling Mitochondrial Calcium Ion Homeostasis Regulation Of Organelle Organization Cellular Aromatic Compound Metabolic Process Regulation Of Cellular Component Organization Nitrogen Compound Metabolic Process DNA-templated Transcription, Elongation Establishment Of Protein Localization To Organelle Anatomical Structure Development Nervous System Development RNA Metabolic Process Diencephalon Development Transcription, DNA-templated
Tagcloud ?		22r availability cholesterol cytochrome cytokine derivative exerted hcg hydroxycholesterol incubated leydig lh linking maximal membranes messenger mitochondria ng nm observation p450scc p55 passes porcine readily steroidogenic testicular testosterone tnfalpha	atf5 burden credible disc1 disordered endophenotypes highlighting intriguing intrinsically lis maf missense nde1 ndel1 neuropsychiatric partners pde4b psychiatric reside schizophrenia striking swedish synonymous sz traf3ip1 unexplored variants ywhae znf365
Tagcloud (Difference) ?		22r availability cholesterol cytochrome cytokine derivative exerted hcg hydroxycholesterol incubated leydig lh linking maximal membranes messenger mitochondria ng nm observation p450scc p55 passes porcine readily steroidogenic testicular testosterone tnfalpha	atf5 burden credible disc1 disordered endophenotypes highlighting intriguing intrinsically lis maf missense nde1 ndel1 neuropsychiatric partners pde4b psychiatric reside schizophrenia striking swedish synonymous sz traf3ip1 unexplored variants ywhae znf365
Tagcloud (Intersection) ?