STAR and CMTM4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		STAR	CMTM4
Description		steroidogenic acute regulatory protein	CKLF like MARVEL transmembrane domain containing 4
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Intermembrane Space Mitochondrial Matrix	Membrane
	Molecular Function	Protein Binding Lipid Binding Cholesterol Binding Cholesterol Transfer Activity	Protein Binding
	Biological Process	Lipid Metabolic Process Steroid Biosynthetic Process Lipid Transport Cholesterol Metabolic Process Glucocorticoid Metabolic Process Intracellular Cholesterol Transport Regulation Of Steroid Biosynthetic Process Positive Regulation Of Bile Acid Biosynthetic Process
Pathways		Pregnenolone biosynthesis Mitochondrial protein degradation
Drugs
Diseases		Congenital adrenal hyperplasia (CAH) 46,XY disorders of sex development (Disorders in androgen synthesis or action), including: Congenital adrenal hyperplasias; Leydig cell hypoplasia; Androgen insensitivity syndrome (AIS)
GWAS		Menopause (age at onset) ( 26414677) Orthostatic hypotension ( 24124408) Schizophrenia ( 29483656)
Interacting Genes		12 interacting genes: AGTRAP CCHCR1 CMTM4 DGAT2L6 FEZ1 LIPE MAGEA11 MAPK3 NUCB2 RABEP1 SMPD2 STX8	20 interacting genes: APOA4 APPL1 COQ8A DAPK1 DGCR6L DIABLO HSBP1L1 MIDN MRPL2 PBX3 PTPN9 SMG9 SNX1 SPG21 SSX3 STAR TBRG4 TCEA2 TTPA ZFYVE21
Entrez ID		6770	146223
HPRD ID		02794	07435
Ensembl ID		ENSG00000147465	ENSG00000183723
Uniprot IDs		P49675 Q6IBK0	Q8IZR5
PDB IDs		3P0L 5OMA 6T5F 6T5H
Enriched GO Terms of Interacting Partners?		Caveola
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