FEZ1 and PDCD7

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		FEZ1	PDCD7
Gene Name		fasciculation and elongation protein zeta 1 (zygin I)	programmed cell death 7
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrion Centrosome Microtubule Plasma Membrane Microtubule Cytoskeleton Axon Dendrite	U12-type Spliceosomal Complex
	Molecular Function	Protein Kinase C Binding Protein Binding Gamma-tubulin Binding Protein N-terminus Binding
	Biological Process	Transport Cell Adhesion Nervous System Development Axon Guidance Positive Regulation Of Neuron Projection Development Establishment Of Mitochondrion Localization Cellular Response To Growth Factor Stimulus	Apoptotic Process RNA Splicing Response To Glucocorticoid Positive Regulation Of T Cell Apoptotic Process Positive Regulation Of Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Schizophrenia ( 22688191 23894747)
Protein-Protein Interactions		57 interactors: BARD1 BORA BRD1 C16orf59 C8orf33 CCL7 CIB1 CLASP2 COL9A2 CSTF2 DIS3L2 DISC1 DNAAF5 DRAP1 FEZ2 GEMIN7 GTF2F1 HAP1 HTATSF1 HTT IMMT KIAA1377 LRIF1 MEST NBR1 NDUFB9 NEK1 OLFML3 P4HB PAM16 PDCD7 PRKCZ PTH PTN PTPRS RAB3GAP1 RAB3GAP2 RAI14 RIF1 SAP30L SCOC SERPINH1 SMARCD1 SMC3 SMEK2 STAR TAC3 TAF1D TAF9 TBC1D25 TLK2 TOMM20 TTR TXNDC9 UBE4B WWC1 ZNF251	6 interactors: APP CALM1 FEZ1 FEZ2 HAP1 PRPF40A
Entrez ID		9638	10081
HPRD ID		09212	09736
Ensembl ID		ENSG00000149557	ENSG00000090470
Uniprot IDs		Q99689	Q6IEG3 Q8N8D1
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Endoplasmic Reticulum Tubular Network Organization Organelle Organization Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Regulation Of Cellular Process Vesicle Transport Along Microtubule Cell Cycle Mitotic Cell Cycle Microtubule-based Process Microtubule Cytoskeleton Organization Regulation Of Metabolic Process Response To Radiation Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Heterocycle Metabolic Process Cellular Process Cellular Homeostasis Organelle Transport Along Microtubule Positive Regulation Of Metabolic Process Response To Ionizing Radiation Response To Stimulus Movement Of Cell Or Subcellular Component Cell Division Regulation Of Intracellular Signal Transduction Cell Cycle Process Regulation Of Synaptic Plasticity Nucleobase-containing Compound Metabolic Process Cellular Response To DNA Damage Stimulus Regulation Of Synaptic Transmission Regulation Of Microtubule-based Process Response To Abiotic Stimulus Cellular Nitrogen Compound Metabolic Process Establishment Or Maintenance Of Cell Polarity Cellular Metabolic Process Mitotic Nuclear Division Mitotic Cell Cycle Process Homeostatic Process Regulation Of Signal Transduction Regulation Of Signaling Mitochondrial Calcium Ion Homeostasis Regulation Of Organelle Organization Cellular Aromatic Compound Metabolic Process Regulation Of Cellular Component Organization Nitrogen Compound Metabolic Process DNA-templated Transcription, Elongation Establishment Of Protein Localization To Organelle Anatomical Structure Development Nervous System Development RNA Metabolic Process Diencephalon Development Transcription, DNA-templated	Regulation Of Cell Cycle Process Movement Of Cell Or Subcellular Component Positive Regulation Of Calcium Ion Transmembrane Transporter Activity Positive Regulation Of Cation Channel Activity Regulation Of Cell Cycle Nervous System Development Exocytosis Positive Regulation Of Ion Transmembrane Transporter Activity Axon Cargo Transport Cell Projection Organization Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Transporter Activity Axon Guidance Positive Regulation Of Cell Cycle Phase Transition Regulation Of Cytokinesis Regulation Of Calcium Ion Transmembrane Transport Regulation Of Calcium Ion Transmembrane Transporter Activity Locomotion Platelet Degranulation Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Cation Channel Activity Regulation Of Cell Morphogenesis Positive Regulation Of Ion Transmembrane Transport Regulation Of ERBB Signaling Pathway Secretion By Cell Axonogenesis Positive Regulation Of Calcium Ion Transport Positive Regulation Of Neurotrophin Production Positive Regulation Of Nonmotile Primary Cilium Assembly Generation Of Neurons Axon Development Cellular Response To Growth Factor Stimulus Cell Morphogenesis Involved In Neuron Differentiation Response To Growth Factor Chemotaxis Neurogenesis Positive Regulation Of Mitotic Cell Cycle Secretion Regulation Of Receptor Activity Neuron Projection Morphogenesis Response To External Stimulus Microtubule-based Transport Regulation Of Neurogenesis Synaptic Growth At Neuromuscular Junction Cytoskeleton-dependent Intracellular Transport Cell Morphogenesis Involved In Differentiation Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Brain Development Establishment Of Localization In Cell
Tagcloud ?		atf5 burden credible disc1 disordered endophenotypes highlighting intriguing intrinsically lis maf missense nde1 ndel1 neuropsychiatric partners pde4b psychiatric reside schizophrenia striking swedish synonymous sz traf3ip1 unexplored variants ywhae znf365	accurate aml amlcg ang2 atcay ca6 cn courses cr cytogenetically discriminated fam3a fis1 german ggt5 hence improving increasingly klrf1 numerous os predicting prediction prognosis published rfs seem shorter unsatisfied
Tagcloud (Difference) ?		atf5 burden credible disc1 disordered endophenotypes highlighting intriguing intrinsically lis maf missense nde1 ndel1 neuropsychiatric partners pde4b psychiatric reside schizophrenia striking swedish synonymous sz traf3ip1 unexplored variants ywhae znf365	accurate aml amlcg ang2 atcay ca6 cn courses cr cytogenetically discriminated fam3a fis1 german ggt5 hence improving increasingly klrf1 numerous os predicting prediction prognosis published rfs seem shorter unsatisfied
Tagcloud (Intersection) ?