FEZ1 and BORA

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		FEZ1	BORA
Gene Name		fasciculation and elongation protein zeta 1 (zygin I)	bora, aurora kinase A activator
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrion Centrosome Microtubule Plasma Membrane Microtubule Cytoskeleton Axon Dendrite	Cytosol
	Molecular Function	Protein Kinase C Binding Protein Binding Gamma-tubulin Binding Protein N-terminus Binding	Protein Binding Protein Kinase Binding
	Biological Process	Transport Cell Adhesion Nervous System Development Axon Guidance Positive Regulation Of Neuron Projection Development Establishment Of Mitochondrion Localization Cellular Response To Growth Factor Stimulus	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Mitotic Nuclear Division Regulation Of Mitotic Nuclear Division Regulation Of Protein Localization Cell Division Regulation Of Mitotic Spindle Organization
Pathways			G2/M Transition Mitotic G2-G2/M phases Regulation of PLK1 Activity at G2/M Transition Cell Cycle, Mitotic
Drugs
Diseases
GWAS		Schizophrenia ( 22688191 23894747)
Protein-Protein Interactions		57 interactors: BARD1 BORA BRD1 C16orf59 C8orf33 CCL7 CIB1 CLASP2 COL9A2 CSTF2 DIS3L2 DISC1 DNAAF5 DRAP1 FEZ2 GEMIN7 GTF2F1 HAP1 HTATSF1 HTT IMMT KIAA1377 LRIF1 MEST NBR1 NDUFB9 NEK1 OLFML3 P4HB PAM16 PDCD7 PRKCZ PTH PTN PTPRS RAB3GAP1 RAB3GAP2 RAI14 RIF1 SAP30L SCOC SERPINH1 SMARCD1 SMC3 SMEK2 STAR TAC3 TAF1D TAF9 TBC1D25 TLK2 TOMM20 TTR TXNDC9 UBE4B WWC1 ZNF251	4 interactors: AURKA BTRC FEZ1 FGFR3
Entrez ID		9638	79866
HPRD ID		09212	13389
Ensembl ID		ENSG00000149557	ENSG00000136122
Uniprot IDs		Q99689	B4DQ30 B5LMG6 Q6PGQ7
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Endoplasmic Reticulum Tubular Network Organization Organelle Organization Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Regulation Of Cellular Process Vesicle Transport Along Microtubule Cell Cycle Mitotic Cell Cycle Microtubule-based Process Microtubule Cytoskeleton Organization Regulation Of Metabolic Process Response To Radiation Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Heterocycle Metabolic Process Cellular Process Cellular Homeostasis Organelle Transport Along Microtubule Positive Regulation Of Metabolic Process Response To Ionizing Radiation Response To Stimulus Movement Of Cell Or Subcellular Component Cell Division Regulation Of Intracellular Signal Transduction Cell Cycle Process Regulation Of Synaptic Plasticity Nucleobase-containing Compound Metabolic Process Cellular Response To DNA Damage Stimulus Regulation Of Synaptic Transmission Regulation Of Microtubule-based Process Response To Abiotic Stimulus Cellular Nitrogen Compound Metabolic Process Establishment Or Maintenance Of Cell Polarity Cellular Metabolic Process Mitotic Nuclear Division Mitotic Cell Cycle Process Homeostatic Process Regulation Of Signal Transduction Regulation Of Signaling Mitochondrial Calcium Ion Homeostasis Regulation Of Organelle Organization Cellular Aromatic Compound Metabolic Process Regulation Of Cellular Component Organization Nitrogen Compound Metabolic Process DNA-templated Transcription, Elongation Establishment Of Protein Localization To Organelle Anatomical Structure Development Nervous System Development RNA Metabolic Process Diencephalon Development Transcription, DNA-templated	Negative Regulation Of Smoothened Signaling Pathway Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Neuron Projection Morphogenesis Regulation Of Smoothened Signaling Pathway Anatomical Structure Morphogenesis G2/M Transition Of Mitotic Cell Cycle Regulation Of Mitotic Nuclear Division Neuron Projection Development Negative Regulation Of Spindle Checkpoint Fibroblast Growth Factor Receptor Apoptotic Signaling Pathway Cell Projection Morphogenesis Regulation Of Cell Development Positive Regulation Of Cell Differentiation Cell Part Morphogenesis Positive Regulation Of Protein Ubiquitination Regulation Of Protein Stability Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Developmental Growth Involved In Morphogenesis Positive Regulation Of Cellular Protein Catabolic Process Regulation Of Cell Cycle Neuron Development Spindle Assembly Involved In Female Meiosis I Cell Morphogenesis Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Cellular Protein Metabolic Process Neuron Differentiation Regulation Of Protein Ubiquitination Cell Projection Organization Protein Autophosphorylation Spindle Assembly Involved In Meiosis Positive Regulation Of Protein Catabolic Process Positive Regulation Of Protein Metabolic Process Spindle Stabilization Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Cell Division Proteasomal Protein Catabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Cell Cycle Phase Transition Developmental Growth Positive Regulation Of Proteolysis Alveolar Secondary Septum Development System Development Axonogenesis Involved In Innervation Generation Of Neurons Regulation Of Cell Differentiation Positive Regulation Of MAPKKK Cascade By Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Oocyte Maturation Neurogenesis Meiotic Spindle Organization
Tagcloud ?		atf5 burden credible disc1 disordered endophenotypes highlighting intriguing intrinsically lis maf missense nde1 ndel1 neuropsychiatric partners pde4b psychiatric reside schizophrenia striking swedish synonymous sz traf3ip1 unexplored variants ywhae znf365	3a 4a bodipy bt compound confocal conjugate conjugated conjugation diaza difluoro dimethyl egfrs fluorescently her3 heterodimer indacene indication internalization ligation lyso modulated nearly partner peptidomimetic proximity skbr stays tracker
Tagcloud (Difference) ?		atf5 burden credible disc1 disordered endophenotypes highlighting intriguing intrinsically lis maf missense nde1 ndel1 neuropsychiatric partners pde4b psychiatric reside schizophrenia striking swedish synonymous sz traf3ip1 unexplored variants ywhae znf365	3a 4a bodipy bt compound confocal conjugate conjugated conjugation diaza difluoro dimethyl egfrs fluorescently her3 heterodimer indacene indication internalization ligation lyso modulated nearly partner peptidomimetic proximity skbr stays tracker
Tagcloud (Intersection) ?