TRAF4 and KRT40

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TRAF4	KRT40
Gene Name		TNF receptor-associated factor 4	keratin 40, type I
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytoskeleton Plasma Membrane Tight Junction Perinuclear Region Of Cytoplasm	Intermediate Filament
	Molecular Function	DNA Binding Ubiquitin-protein Transferase Activity Tumor Necrosis Factor Receptor Binding Protein Binding Zinc Ion Binding Protein Kinase Binding Ubiquitin Protein Ligase Binding Thioesterase Binding WW Domain Binding	Structural Molecule Activity
	Biological Process	Apoptotic Process Signal Transduction Activation Of NF-kappaB-inducing Kinase Activity Respiratory Gaseous Exchange Protein Ubiquitination Respiratory Tube Development Regulation Of Apoptotic Process Positive Regulation Of Protein Kinase Activity Positive Regulation Of JNK Cascade Positive Regulation Of Protein Homodimerization Activity
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		69 interactors: ALKBH4 ARNT2 BAHD1 BANP BCKDK BCL6B BYSL CALCOCO2 CBL CBLC CCHCR1 CENPE CHUK DTX3 EXOC7 FBXL18 FTH1 GORASP2 GPRASP1 HOMEZ IRAK1 ISYNA1 KANSL1 KDM1A KRT31 KRT40 LTBR MAGED1 MAP3K4 MRPL28 NCF1 NGFR NGFRAP1 NOS1AP NPAS2 PDE4DIP PKD1P1 PLSCR1 PSMC3 QARS REXO1L6P RNF114 RPS6KB1 SIGLEC7 SMURF1 SMURF2 SORBS2 SPDL1 SUMO1 TARBP2 TBC1D7 TBC1D8 TGFB1I1 TICAM1 TNFRSF4 TP53BP2 TRAF6 TRIM37 TYK2 UBE2I UBL4A UBL4B USP7 WBP11 WWP1 WWP2 ZNF3 ZNF512B ZNF581	313 interactors: ADAMTSL3 AEN AES AKAP17A ALDH3B1 ALS2CR11 ANKRD36BP1 AP1M1 AQP1 AQP5 ARID5A ARMC7 ARSI ASMTL ATPAF2 AVPI1 BAHD1 BARD1 BCAS2 BEX2 BMS1P5 BYSL C10orf62 C11orf87 C14orf105 C19orf57 C19orf66 C19orf73 C1orf109 C1orf216 C20orf195 C22orf46 C5orf60 C6orf165 C6orf226 C8orf48 CA6 CARD9 CATIP CBX8 CCDC112 CCDC120 CCDC146 CCDC185 CCDC26 CCDC93 CCER1 CCHCR1 CCNG1 CD33 CDC20B CDK18 CDK5R1 CELA2B CEP57 CEP57L1 CHCHD2 CHCHD3 CHIC2 CLEC18A CNTF COL8A1 COMT COX5A CREB5 CTSZ CWF19L2 CYCS CYTH4 DAAM2 DCDC2B DCX DDX6 DLGAP2 DMRT3 DOCK2 DOCK8 DTNB EIF4E2 EXOC3-AS1 FAM107A FAM124B FAM214A FAM27E3 FAM64A FAM71C FAM74A4 FAM90A1 FARS2 FASLG FBF1 FBXL18 FBXO34 FBXW5 FKBP1B FOXB1 FRG1 GATA2 GATAD2A GEM GFOD1 GGN GLIDR GNAI2 GNG5 GOLGA6L2 GPATCH2L GTF3C5 GUCD1 HAUS1 HBA2 HBZ HCK HDAC4 HGS HOXA1 HSPA12B HSPD1 ING5 INPP5D IQUB ISCU ITGB5 JOSD1 KAT5 KCTD9 KIFC3 KLHL38 KPNA2 KRT2 KRT20 KRT4 KRT5 KRT6A KRT6C KRT71 KRT72 KRT8 KRT81 LAGE3 LCE3E LENG1 LIMS2 LIN37 LINC00636 LINC01588 LMF2 LMO1 LMO2 LMO4 LOC149950 LRCH4 MAB21L2 MAGOHB MAPKBP1 MARK4 MED8 METTL17 MFAP1 MOB3C MOS MRPL11 MTA1 MXI1 NAB2 NAPRT NDEL1 NEK6 NFKBID NINJ1 NPBWR2 NPPB NR1D2 NXF1 OPCML OTUB2 PDLIM5 PGLS PHF21A PIGS PIN1 PKD2 POLDIP3 POLL POM121L8P POP5 PPP1R18 PRAM1 PRKAA1 PRKAB2 PRPF31 PSMA1 PSMC5 PTGER3 PTPMT1 PXMP2 QPRT RAB3IL1 RAB3IP RAC1 RASSF5 RBM41 RCOR3 RECK RNF213 RPL11 RSPH14 RTP5 RWDD2B SCOC SEMA4C SETD5 SH2D4A SHC3 SIRPA SLC25A10 SLIRP SLU7 SMARCE1 SMCO4 SNAI1 SNHG11 SNRPB SNW1 SPATA24 SPEF1 SPG7 SRSF2 SSX2 SSX2IP SYT6 TAPBPL TBC1D16 TBC1D22B TCEA2 TCEB3 TCHP THAP7 TIE1 TMEM231 TMEM241 TMSB4X TNIP3 TNNT1 TRAF4 TRIM42 TROAP TRPV6 TSC22D4 TSGA10IP TSHZ3 TTC23 TTC25 TTLL10 TXLNA TXN2 TXNDC5 TYK2 TYRO3 UACA UBASH3A UCMA USHBP1 USP2 USP21 UTP14C UTP23 UXT WDR25 WT1 WT1-AS ZBTB16 ZBTB24 ZBTB38 ZC2HC1C ZFHX3 ZFP2 ZFP69B ZFYVE21 ZFYVE26 ZGPAT ZMAT2 ZNF101 ZNF124 ZNF138 ZNF165 ZNF20 ZNF202 ZNF230 ZNF250 ZNF26 ZNF266 ZNF286A ZNF317 ZNF329 ZNF337 ZNF417 ZNF439 ZNF446 ZNF488 ZNF490 ZNF564 ZNF569 ZNF581 ZNF587 ZNF625 ZNF655 ZNF697 ZNF702P ZNF792 ZNF844 ZNRF2P1 ZSCAN21
Entrez ID		9618	125115
HPRD ID		03915	08304
Ensembl ID		ENSG00000076604	ENSG00000204889
Uniprot IDs		Q9BUZ4	Q6A162
PDB IDs		2EOD 2YUC 4M4E
Enriched GO Terms of Interacting Partners?		Protein Modification By Small Protein Conjugation Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Protein Ubiquitination Regulation Of Gene Expression Regulation Of Signal Transduction Regulation Of Metabolic Process Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Nucleic Acid-templated Transcription Regulation Of Signaling Regulation Of RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Transcription, DNA-templated Response To Growth Factor Regulation Of Protein Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Ubiquitin-dependent SMAD Protein Catabolic Process Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Signal Transduction Cellular Protein Modification Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Protein Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Cellular Protein Metabolic Process Cellular Response To Growth Factor Stimulus Regulation Of Innate Immune Response Negative Regulation Of Transcription, DNA-templated Response To Organic Substance Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Programmed Cell Death Proteolysis Involved In Cellular Protein Catabolic Process Response To Cytokine Cellular Protein Catabolic Process Cell Death Death Protein Metabolic Process Cellular Response To Organic Substance Negative Regulation Of Cellular Metabolic Process Positive Regulation Of NF-kappaB Transcription Factor Activity Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Cellular Metabolic Process TRIF-dependent Toll-like Receptor Signaling Pathway Neurotrophin Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process Protein Catabolic Process	Transcription, DNA-templated RNA Biosynthetic Process Gene Expression RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Heterocycle Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Cellular Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Cellular Metabolic Process Transcription From RNA Polymerase II Promoter Cellular Process Regulation Of Transcription From RNA Polymerase II Promoter Developmental Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Defense Response To Virus By Virus Regulation Of Cell Death Regulation Of Protein Metabolic Process Anatomical Structure Development Regulation Of Apoptotic Process Bicarbonate Transport Cell Death Death Centrosome Organization Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Intermediate Filament Cytoskeleton Organization Cytoskeleton Organization Microtubule Organizing Center Organization Positive Regulation Of Cellular Protein Metabolic Process Intermediate Filament-based Process Organelle Organization Multicellular Organismal Development
Tagcloud ?		bcr cart cd40 cd54 cd95 ciap2 define dr3 driven effector engagement fas icam linking mapk mapkapk minimal p38 permeable perturbed potentiating requirement responsive sb203580 selectively stimulates tonsillar traf1 unaffected
Tagcloud (Difference) ?		bcr cart cd40 cd54 cd95 ciap2 define dr3 driven effector engagement fas icam linking mapk mapkapk minimal p38 permeable perturbed potentiating requirement responsive sb203580 selectively stimulates tonsillar traf1 unaffected
Tagcloud (Intersection) ?