BAG3 and TINF2

Number of citations of the paper that reports this interaction (PMID 21044950)
9

Data Source:
BioGRID (two hybrid)

		BAG3	TINF2
Gene Name		BCL2-associated athanogene 3	TERF1 (TRF1)-interacting nuclear factor 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Z Disc Neuron Projection	Chromosome, Telomeric Region Nuclear Telomere Cap Complex Nucleus Nucleoplasm Perinucleolar Chromocenter Nuclear Matrix
	Molecular Function	Protein Binding Protein Complex Binding Chaperone Binding	DNA Binding Protein Binding Telomeric DNA Binding
	Biological Process	Protein Folding Brain Development Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Negative Regulation Of Striated Muscle Cell Apoptotic Process Spinal Cord Development Negative Regulation Of Apoptotic Process Protein Stabilization Cellular Response To Mechanical Stimulus Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand	Telomere Maintenance Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Protein ADP-ribosylation Telomere Assembly Positive Regulation Of Telomere Maintenance Negative Regulation Of Telomere Maintenance Via Telomerase Protein Localization To Chromosome Negative Regulation Of Epithelial Cell Proliferation Protein Localization To Chromosome, Telomeric Region
Pathways			Telomere Maintenance Packaging Of Telomere Ends DNA Damage/Telomere Stress Induced Senescence Chromosome Maintenance Cellular Senescence Meiotic synapsis
Drugs
Diseases
GWAS		Dilated cardiomyopathy ( 21459883)
Protein-Protein Interactions		20 interactors: ACD ARRDC3 BCL2 CRYAB DAZAP2 DVL2 DYNLT1 FAM189A2 HSPA1A HSPA8 HSPB8 LITAF MAGED1 PDE9A PLCG1 POT1 SF3B4 TINF2 TNK2 WNK1	88 interactors: ACD ACOT7 ACTB ADA AFAP1L2 AIPL1 AK1 ANKMY2 ANXA4 ANXA5 APOBEC3F APPL2 ARHGDIA ARID3B BAG3 BIN2 CALD1 CCDC43 CCDC9 CKB CLK3 CPNE3 CRYGS CTTN DBN1 DCX DHFRL1 DPP3 EEF1D EIF4B ENO2 FAM131B FERMT3 FKBP6 GAPDH GNMT HNMT HOXA3 HSP90AB1 IPO5 KCTD17 LASP1 LDHA LGALSL LTA4H MAP2K3 NCDN NOL3 NUDC NUDCD2 OR2H1 PAGE2 PAK1IP1 PEX5 PFKP PGM1 PGM2 PHPT1 PKM POT1 PPP1R2 PPP6R3 PRKCB REM2 RGS14 RPSA SARS SCRN2 SIAH2 STUB1 SULT1C2 TAGLN TBL1X TERF1 TERF2 TOMM34 TPP1 TRIM15 TRIM16 TRIP10 TUBB TUBB4B TXNDC17 UCHL1 VIPR1 YWHAG ZFP36L1 ZNF790
Entrez ID		9531	26277
HPRD ID		04860	16056
Ensembl ID		ENSG00000151929	ENSG00000092330
Uniprot IDs		O95817	B4DFJ1 Q9BSI4
PDB IDs			3BQO 3BU8
Enriched GO Terms of Interacting Partners?		Telomere Assembly Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Catalytic Activity Regulation Of Telomere Maintenance Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Transferase Activity Regulation Of Cellular Component Organization Negative Regulation Of DNA Replication Protein Localization To Chromosome, Telomeric Region Telomere Capping Positive Regulation Of Telomerase Activity Positive Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Telomere Maintenance Positive Regulation Of Telomere Maintenance Negative Regulation Of Chromosome Organization Positive Regulation Of Protein Modification Process Negative Regulation Of DNA Metabolic Process Regulation Of Telomerase Activity Negative Regulation Of Intracellular Transport Positive Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Catalytic Activity Positive Regulation Of DNA Biosynthetic Process Protein Refolding Regulation Of Protein Phosphorylation Regulation Of DNA Replication Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Phosphorylation Positive Regulation Of DNA Metabolic Process Positive Regulation Of RNA Splicing Negative Regulation Of Cell Growth Negative Regulation Of Transport Regulation Of Glycoprotein Biosynthetic Process Protein Localization To Chromosome Regulation Of Cellular Response To Heat Positive Regulation Of Protein Metabolic Process Telomere Maintenance Via Telomere Lengthening Positive Regulation Of Signal Transduction Regulation Of Intracellular Transport Positive Regulation Of Intracellular Signal Transduction Intracellular Signal Transduction Regulation Of Cellular Process Regulation Of Phosphorylation Regulation Of Organ Morphogenesis Positive Regulation Of Phosphorylation	Negative Regulation Of Telomere Maintenance Telomere Capping Negative Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomerase Activity Glycolytic Process Protection From Non-homologous End Joining At Telomere Carbohydrate Catabolic Process Negative Regulation Of DNA Replication Telomere Assembly Catabolic Process Negative Regulation Of DNA Metabolic Process Protein Localization To Chromosome, Telomeric Region Negative Regulation Of Catalytic Activity Positive Regulation Of Telomerase Activity Pyruvate Metabolic Process Telomere Maintenance Telomere Maintenance Via Telomerase Pathogenesis Generation Of Precursor Metabolites And Energy Glucose Metabolic Process Positive Regulation Of Single-stranded Telomeric DNA Binding Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Negative Regulation Of Chromosome Organization Small Molecule Metabolic Process Organic Acid Metabolic Process Regulation Of DNA Biosynthetic Process Regulation Of Catalytic Activity Carboxylic Acid Metabolic Process Age-dependent Telomere Shortening Telomeric Loop Formation Nervous System Development Regulation Of Signaling Positive Regulation Of DNA Biosynthetic Process Glycogen Metabolic Process RNA-dependent DNA Replication Nucleoside Metabolic Process Telomere Maintenance Via Telomere Shortening Regulation Of Signal Transduction Hexose Metabolic Process Cellular Process Regulation Of DNA Replication Monocarboxylic Acid Metabolic Process Cellular Carbohydrate Metabolic Process Response To Stimulus Protein Localization To Chromosome Organelle Organization Telomere Maintenance Via Telomere Lengthening Polysaccharide Metabolic Process
Tagcloud ?		athanogene bcl2 cancerous developmentally e3 fnbp4 formin guanylatekinase ligase magi1 modulator nedd4 oncogene oncogenic oxidoreductase pdz property rab2a sgsm3 tumorigenic unchanged wbp2 wbp2nl ww wwox wwp1 wwtr1 yap1 yes	acd add broader clustered clustering convincingly correction cosegregated ends families fisher germline inactivating lod logarithm melanoma nonsense pot1 predispose probands q320x r364x shelterin tailed terf1 terf2 terf2ip yates
Tagcloud (Difference) ?		athanogene bcl2 cancerous developmentally e3 fnbp4 formin guanylatekinase ligase magi1 modulator nedd4 oncogene oncogenic oxidoreductase pdz property rab2a sgsm3 tumorigenic unchanged wbp2 wbp2nl ww wwox wwp1 wwtr1 yap1 yes	acd add broader clustered clustering convincingly correction cosegregated ends families fisher germline inactivating lod logarithm melanoma nonsense pot1 predispose probands q320x r364x shelterin tailed terf1 terf2 terf2ip yates
Tagcloud (Intersection) ?