BAG3 and FAM189A2

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
HPRD (two hybrid)

		BAG3	FAM189A2
Gene Name		BCL2-associated athanogene 3	family with sequence similarity 189, member A2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Z Disc Neuron Projection	Cellular_component Integral Component Of Membrane
	Molecular Function	Protein Binding Protein Complex Binding Chaperone Binding	Molecular_function
	Biological Process	Protein Folding Brain Development Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Negative Regulation Of Striated Muscle Cell Apoptotic Process Spinal Cord Development Negative Regulation Of Apoptotic Process Protein Stabilization Cellular Response To Mechanical Stimulus Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand	Biological_process
Pathways
Drugs
Diseases
GWAS		Dilated cardiomyopathy ( 21459883)
Protein-Protein Interactions		20 interactors: ACD ARRDC3 BCL2 CRYAB DAZAP2 DVL2 DYNLT1 FAM189A2 HSPA1A HSPA8 HSPB8 LITAF MAGED1 PDE9A PLCG1 POT1 SF3B4 TINF2 TNK2 WNK1	9 interactors: BAG3 CALCOCO2 SFN STAM2 TAX1BP1 UBQLN1 UBXN1 WWP1 WWP2
Entrez ID		9531	9413
HPRD ID		04860	16255
Ensembl ID		ENSG00000151929	ENSG00000135063
Uniprot IDs		O95817	Q15884 Q8WU02
PDB IDs
Enriched GO Terms of Interacting Partners?		Telomere Assembly Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Catalytic Activity Regulation Of Telomere Maintenance Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Transferase Activity Regulation Of Cellular Component Organization Negative Regulation Of DNA Replication Protein Localization To Chromosome, Telomeric Region Telomere Capping Positive Regulation Of Telomerase Activity Positive Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Telomere Maintenance Positive Regulation Of Telomere Maintenance Negative Regulation Of Chromosome Organization Positive Regulation Of Protein Modification Process Negative Regulation Of DNA Metabolic Process Regulation Of Telomerase Activity Negative Regulation Of Intracellular Transport Positive Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Catalytic Activity Positive Regulation Of DNA Biosynthetic Process Protein Refolding Regulation Of Protein Phosphorylation Regulation Of DNA Replication Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Phosphorylation Positive Regulation Of DNA Metabolic Process Positive Regulation Of RNA Splicing Negative Regulation Of Cell Growth Negative Regulation Of Transport Regulation Of Glycoprotein Biosynthetic Process Protein Localization To Chromosome Regulation Of Cellular Response To Heat Positive Regulation Of Protein Metabolic Process Telomere Maintenance Via Telomere Lengthening Positive Regulation Of Signal Transduction Regulation Of Intracellular Transport Positive Regulation Of Intracellular Signal Transduction Intracellular Signal Transduction Regulation Of Cellular Process Regulation Of Phosphorylation Regulation Of Organ Morphogenesis Positive Regulation Of Phosphorylation	Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Viral Entry Into Host Cell Entry Into Host Cell Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Interaction With Host Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Viral Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Regulation Of Epidermal Cell Division Protein Catabolic Process Regulation Of Apoptotic Process Regulation Of Cell Death Viral Life Cycle Regulation Of Protein Ubiquitination Cellular Macromolecule Catabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Keratinocyte Development Negative Regulation Of Keratinocyte Proliferation Apoptotic Process Negative Regulation Of Cell Death Negative Regulation Of Cellular Metabolic Process Programmed Cell Death Positive Regulation Of Protein Export From Nucleus Regulation Of Metabolic Process Negative Regulation Of Striated Muscle Cell Apoptotic Process Cell Death Death Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Establishment Of Skin Barrier Apoptotic Signaling Pathway Negative Regulation Of Proteolysis Regulation Of Water Loss Via Skin Negative Regulation Of Protein Processing Positive Regulation Of Epidermal Cell Differentiation Regulation Of Keratinocyte Proliferation Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Protein Processing Response To Stimulus Regulation Of Potassium Ion Transmembrane Transporter Activity Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Protein K63-linked Ubiquitination Regulation Of Protein Export From Nucleus Release Of Cytochrome C From Mitochondria
Tagcloud ?		athanogene bcl2 cancerous developmentally e3 fnbp4 formin guanylatekinase ligase magi1 modulator nedd4 oncogene oncogenic oxidoreductase pdz property rab2a sgsm3 tumorigenic unchanged wbp2 wbp2nl ww wwox wwp1 wwtr1 yap1 yes
Tagcloud (Difference) ?		athanogene bcl2 cancerous developmentally e3 fnbp4 formin guanylatekinase ligase magi1 modulator nedd4 oncogene oncogenic oxidoreductase pdz property rab2a sgsm3 tumorigenic unchanged wbp2 wbp2nl ww wwox wwp1 wwtr1 yap1 yes
Tagcloud (Intersection) ?