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RECQL5 and TIMP1
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
RECQL5
TIMP1
Gene Name
RecQ protein-like 5
TIMP metallopeptidase inhibitor 1
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
DNA-directed RNA Polymerase II, Holoenzyme
Nuclear Membrane
Extracellular Region
Proteinaceous Extracellular Matrix
Basement Membrane
Extracellular Space
Platelet Alpha Granule Lumen
Extracellular Vesicular Exosome
Molecular Function
RNA Polymerase II Core Binding
Nucleic Acid Binding
DNA Helicase Activity
ATP Binding
ATP-dependent Helicase Activity
Protease Binding
Cytokine Activity
Protein Binding
Growth Factor Activity
Metalloendopeptidase Inhibitor Activity
Metal Ion Binding
Biological Process
DNA Metabolic Process
DNA Replication
DNA Repair
DNA Recombination
Mitotic Nuclear Division
DNA Duplex Unwinding
Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter
Cell Division
Chromosome Separation
Platelet Degranulation
Aging
Blood Coagulation
Positive Regulation Of Cell Proliferation
Response To Hormone
Negative Regulation Of Endopeptidase Activity
Extracellular Matrix Disassembly
Platelet Activation
Extracellular Matrix Organization
Response To Cytokine
Negative Regulation Of Apoptotic Process
Response To Peptide Hormone
Negative Regulation Of Metalloenzyme Activity
Negative Regulation Of Membrane Protein Ectodomain Proteolysis
Negative Regulation Of Trophoblast Cell Migration
Regulation Of Integrin-mediated Signaling Pathway
Pathways
Response to elevated platelet cytosolic Ca2+
Activation of Matrix Metalloproteinases
Platelet degranulation
Platelet activation, signaling and aggregation
Degradation of the extracellular matrix
Drugs
Diseases
GWAS
Protein-Protein Interactions
19 interactors:
ADCY10P1
ALDH7A1
BNIPL
CREB1
CUX1
DDX42
EEF1G
ITGB3BP
MAPK8IP1
MRE11A
MTSS1
NBN
PLK1
POLR2A
RAD50
STAMBP
TIMP1
TOP3A
TOP3B
8 interactors:
CD63
ECH1
EEF1B2
MMP1
MMP2
MMP3
MYOC
RECQL5
Entrez ID
9400
7076
HPRD ID
04806
02371
Ensembl ID
ENSG00000108469
ENSG00000102265
Uniprot IDs
B3KQK2
O94762
Q6P4G0
Q8WYH5
B4DJK3
P01033
Q6FGX5
PDB IDs
4BK0
1D2B
1LQN
1OO9
1UEA
2J0T
3MA2
3V96
Enriched GO Terms of Interacting Partners
?
DNA Conformation Change
Positive Regulation Of Protein Autophosphorylation
Meiotic Cell Cycle
Regulation Of Protein Autophosphorylation
G2 DNA Damage Checkpoint
Chromosome Organization
Cellular Response To Stress
Meiotic Nuclear Division
Regulation Of Mitotic Recombination
Telomere Maintenance
Telomere Maintenance Via Telomerase
DNA Duplex Unwinding
DNA Geometric Change
Double-strand Break Repair Via Homologous Recombination
Recombinational Repair
Cell Cycle
Mitotic G2 DNA Damage Checkpoint
Cell Cycle Process
DNA Metabolic Process
Mitotic Cell Cycle Process
DNA Topological Change
RNA-dependent DNA Replication
Organelle Organization
Double-strand Break Repair
Mitotic Cell Cycle
DNA Damage Checkpoint
Regulation Of Kinase Activity
Mitotic Cell Cycle Checkpoint
Telomere Maintenance Via Telomere Lengthening
Cellular Response To DNA Damage Stimulus
Response To Stress
Mitotic Cytokinesis
Reciprocal Meiotic Recombination
Negative Regulation Of Mitotic Cell Cycle
Chromosome Segregation
Cell Cycle Checkpoint
DNA Recombination
Positive Regulation Of Transferase Activity
Reproduction
DNA Repair
Regulation Of Protein Phosphorylation
Regulation Of Catalytic Activity
Regulation Of DNA Recombination
Cellular Nitrogen Compound Metabolic Process
Activation Of APC-Cdc20 Complex Activity
Transcription, RNA-templated
Glycine Betaine Biosynthetic Process From Choline
Adherens Junction Maintenance
Positive Regulation Of Cellular Metabolic Process
Cell Proliferation
Collagen Catabolic Process
Collagen Metabolic Process
Multicellular Organismal Macromolecule Metabolic Process
Multicellular Organismal Metabolic Process
Extracellular Matrix Disassembly
Positive Regulation Of Protein Oligomerization
Regulation Of Protein Oligomerization
Positive Regulation Of Cellular Component Biogenesis
Cellular Response To Amino Acid Stimulus
Extracellular Matrix Organization
Extracellular Structure Organization
ERBB2-ERBB3 Signaling Pathway
Skeletal Muscle Hypertrophy
Response To Amino Acid
ERBB2 Signaling Pathway
Regulation Of Protein Kinase B Signaling
Negative Regulation Of Hydrogen Peroxide Metabolic Process
Positive Regulation Of Protein Complex Assembly
Cellular Response To Acid Chemical
Regulation Of Rubidium Ion Transport
Catabolic Process
Non-canonical Wnt Signaling Pathway Via JNK Cascade
Non-canonical Wnt Signaling Pathway Via MAPK Cascade
Regulation Of Cellular Component Organization
Response To Stress
Positive Regulation Of Oxidative Stress-induced Cell Death
Clustering Of Voltage-gated Sodium Channels
Pigment Granule Maturation
Endosome To Melanosome Transport
Intramembranous Ossification
Skeletal Muscle Adaptation
Bone Trabecula Formation
Positive Regulation Of Integrin-mediated Signaling Pathway
Cellular Pigment Accumulation
Regulation Of Hydrogen Peroxide Metabolic Process
Regulation Of Vascular Endothelial Growth Factor Signaling Pathway
Positive Regulation Of Mitochondrial Depolarization
Negative Regulation Of Stress Fiber Assembly
Ossification
Neuronal Ion Channel Clustering
Blood Vessel Maturation
Negative Regulation Of Actin Filament Bundle Assembly
Cellular Response To Nitric Oxide
Regulation Of Protein Complex Assembly
Response To Nitric Oxide
Bone Trabecula Morphogenesis
Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter
Regulation Of Mitochondrial Depolarization
Positive Regulation Of Receptor Internalization
Negative Regulation Of DNA-templated Transcription, Elongation
Tagcloud
?
accurately
another
applying
associations
biomarker
biomarkers
candidate
classifying
divide
egfr
embedded
escc
esophageal
ihc
kit
multivariate
p110alpha
p85alpha
panel
paraffin
pi3k
poor
prognosis
prognostic
risks
six
squamous
statistical
subgroups
Tagcloud (Difference)
?
accurately
another
applying
associations
biomarker
biomarkers
candidate
classifying
divide
egfr
embedded
escc
esophageal
ihc
kit
multivariate
p110alpha
p85alpha
panel
paraffin
pi3k
poor
prognosis
prognostic
risks
six
squamous
statistical
subgroups
Tagcloud (Intersection)
?