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RECQL5 and NBN
Number of citations of the paper that reports this interaction (PMID
19270065
)
16
Data Source:
BioGRID
(pull down)
RECQL5
NBN
Gene Name
RecQ protein-like 5
nibrin
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
DNA-directed RNA Polymerase II, Holoenzyme
Nuclear Membrane
Nuclear Chromosome, Telomeric Region
Nucleus
Nucleoplasm
Replication Fork
Nucleolus
PML Body
Mre11 Complex
Site Of Double-strand Break
Nuclear Inclusion Body
Molecular Function
RNA Polymerase II Core Binding
Nucleic Acid Binding
DNA Helicase Activity
ATP Binding
ATP-dependent Helicase Activity
Damaged DNA Binding
ATP-dependent DNA Helicase Activity
Protein Binding
Transcription Factor Binding
Protein N-terminus Binding
Biological Process
DNA Metabolic Process
DNA Replication
DNA Repair
DNA Recombination
Mitotic Nuclear Division
DNA Duplex Unwinding
Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter
Cell Division
Chromosome Separation
DNA Damage Checkpoint
Telomere Maintenance
Double-strand Break Repair Via Homologous Recombination
Blastocyst Growth
DNA Repair
Double-strand Break Repair
Cell Cycle Arrest
Mitotic Cell Cycle Checkpoint
Mitotic G2 DNA Damage Checkpoint
Cell Proliferation
Regulation Of DNA-dependent DNA Replication Initiation
DNA Damage Response, Signal Transduction By P53 Class Mediator
Positive Regulation Of Protein Autophosphorylation
DNA Duplex Unwinding
Positive Regulation Of Kinase Activity
Isotype Switching
Neuromuscular Process Controlling Balance
Meiotic Cell Cycle
Intrinsic Apoptotic Signaling Pathway
Pathways
ATM mediated phosphorylation of repair proteins
Meiotic recombination
DNA Damage/Telomere Stress Induced Senescence
MRN complex relocalizes to nuclear foci
ATM mediated response to DNA double-strand break
Cellular Senescence
Assembly of the RAD50-MRE11-NBS1 complex at DNA double-strand breaks
Homologous Recombination Repair
Recruitment of repair and signaling proteins to double-strand breaks
Homologous recombination repair of replication-independent double-strand breaks
Double-Strand Break Repair
Drugs
Diseases
GWAS
Protein-Protein Interactions
19 interactors:
ADCY10P1
ALDH7A1
BNIPL
CREB1
CUX1
DDX42
EEF1G
ITGB3BP
MAPK8IP1
MRE11A
MTSS1
NBN
PLK1
POLR2A
RAD50
STAMBP
TIMP1
TOP3A
TOP3B
27 interactors:
ATF2
ATM
ATR
BRCA1
CCNE1
CDK9
CHEK2
DCLRE1C
EP300
FANCD2
H2AFX
MDC1
MRE11A
NCL
PRKDC
RAD18
RAD50
RECQL5
RNF8
SIRT1
TERF1
TLK1
TREX1
UBE2D1
UBE2N
XRCC4
XRCC5
Entrez ID
9400
4683
HPRD ID
04806
04050
Ensembl ID
ENSG00000108469
ENSG00000104320
Uniprot IDs
B3KQK2
O94762
Q6P4G0
Q8WYH5
O60934
PDB IDs
4BK0
Enriched GO Terms of Interacting Partners
?
DNA Conformation Change
Positive Regulation Of Protein Autophosphorylation
Meiotic Cell Cycle
Regulation Of Protein Autophosphorylation
G2 DNA Damage Checkpoint
Chromosome Organization
Cellular Response To Stress
Meiotic Nuclear Division
Regulation Of Mitotic Recombination
Telomere Maintenance
Telomere Maintenance Via Telomerase
DNA Duplex Unwinding
DNA Geometric Change
Double-strand Break Repair Via Homologous Recombination
Recombinational Repair
Cell Cycle
Mitotic G2 DNA Damage Checkpoint
Cell Cycle Process
DNA Metabolic Process
Mitotic Cell Cycle Process
DNA Topological Change
RNA-dependent DNA Replication
Organelle Organization
Double-strand Break Repair
Mitotic Cell Cycle
DNA Damage Checkpoint
Regulation Of Kinase Activity
Mitotic Cell Cycle Checkpoint
Telomere Maintenance Via Telomere Lengthening
Cellular Response To DNA Damage Stimulus
Response To Stress
Mitotic Cytokinesis
Reciprocal Meiotic Recombination
Negative Regulation Of Mitotic Cell Cycle
Chromosome Segregation
Cell Cycle Checkpoint
DNA Recombination
Positive Regulation Of Transferase Activity
Reproduction
DNA Repair
Regulation Of Protein Phosphorylation
Regulation Of Catalytic Activity
Regulation Of DNA Recombination
Cellular Nitrogen Compound Metabolic Process
Activation Of APC-Cdc20 Complex Activity
Transcription, RNA-templated
Glycine Betaine Biosynthetic Process From Choline
Adherens Junction Maintenance
Positive Regulation Of Cellular Metabolic Process
Cell Proliferation
Cellular Response To DNA Damage Stimulus
DNA Repair
Cellular Response To Stress
DNA Metabolic Process
Double-strand Break Repair
DNA Recombination
Response To Ionizing Radiation
Response To Stress
Cell Cycle Process
Cell Cycle
Double-strand Break Repair Via Homologous Recombination
Recombinational Repair
Nucleobase-containing Compound Metabolic Process
Response To Radiation
Cell Cycle Checkpoint
Chromosome Organization
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Response To Abiotic Stimulus
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
DNA Damage Checkpoint
DNA Replication
Telomere Maintenance
Positive Regulation Of Response To DNA Damage Stimulus
Regulation Of Response To DNA Damage Stimulus
Cellular Response To Stimulus
Mitotic Cell Cycle Process
Regulation Of Cell Cycle
Mitotic Cell Cycle Checkpoint
Mitotic Cell Cycle
Organelle Organization
Response To Stimulus
Response To Gamma Radiation
Double-strand Break Repair Via Nonhomologous End Joining
Negative Regulation Of Cell Cycle
Regulation Of Chromosome Organization
Regulation Of DNA Repair
Negative Regulation Of Mitotic Cell Cycle
Intra-S DNA Damage Checkpoint
Regulation Of Mitotic Cell Cycle
Positive Regulation Of DNA Repair
Negative Regulation Of Cellular Metabolic Process
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Mitotic DNA Damage Checkpoint
Negative Regulation Of DNA Metabolic Process
Mitotic DNA Integrity Checkpoint
Negative Regulation Of DNA Replication
Regulation Of Nitrogen Compound Metabolic Process
Cellular Metabolic Process
Tagcloud
?
5yrs
atm
atr
brfr
category
cohorts
ddr
decisions
fail
gains
gleason
guided
igrt
mre11a
nibrin
pca
precision
predictor
predicts
prkdc
prostatectomy
psa
rad50
radioresistance
radiotherapy
radp
sensing
sensors
wald
Tagcloud (Difference)
?
5yrs
atm
atr
brfr
category
cohorts
ddr
decisions
fail
gains
gleason
guided
igrt
mre11a
nibrin
pca
precision
predictor
predicts
prkdc
prostatectomy
psa
rad50
radioresistance
radiotherapy
radp
sensing
sensors
wald
Tagcloud (Intersection)
?