RECQL5 and MTSS1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RECQL5	MTSS1
Gene Name		RecQ protein-like 5	metastasis suppressor 1
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm DNA-directed RNA Polymerase II, Holoenzyme Nuclear Membrane	Ruffle Cytoplasm Adherens Junction Actin Cytoskeleton Endocytic Vesicle
	Molecular Function	RNA Polymerase II Core Binding Nucleic Acid Binding DNA Helicase Activity ATP Binding ATP-dependent Helicase Activity	Actin Monomer Binding Receptor Binding Protein Binding Identical Protein Binding Actin Filament Binding
	Biological Process	DNA Metabolic Process DNA Replication DNA Repair DNA Recombination Mitotic Nuclear Division DNA Duplex Unwinding Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter Cell Division Chromosome Separation	In Utero Embryonic Development Movement Of Cell Or Subcellular Component Plasma Membrane Organization Cell Adhesion Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Magnesium Ion Homeostasis Microspike Assembly Actin Cytoskeleton Organization Actin Filament Polymerization Bone Mineralization Positive Regulation Of Actin Filament Bundle Assembly Adherens Junction Maintenance Negative Regulation Of Epithelial Cell Proliferation Renal Tubule Morphogenesis Cellular Response To Fluid Shear Stress Glomerulus Morphogenesis Nephron Tubule Epithelial Cell Differentiation Epithelial Cell Proliferation Involved In Renal Tubule Morphogenesis
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		19 interactors: ADCY10P1 ALDH7A1 BNIPL CREB1 CUX1 DDX42 EEF1G ITGB3BP MAPK8IP1 MRE11A MTSS1 NBN PLK1 POLR2A RAD50 STAMBP TIMP1 TOP3A TOP3B	3 interactors: HTT PTPRD RECQL5
Entrez ID		9400	9788
HPRD ID		04806	12243
Ensembl ID		ENSG00000108469	ENSG00000170873
Uniprot IDs		B3KQK2 O94762 Q6P4G0 Q8WYH5	O43312
PDB IDs		4BK0	2D1K
Enriched GO Terms of Interacting Partners?		DNA Conformation Change Positive Regulation Of Protein Autophosphorylation Meiotic Cell Cycle Regulation Of Protein Autophosphorylation G2 DNA Damage Checkpoint Chromosome Organization Cellular Response To Stress Meiotic Nuclear Division Regulation Of Mitotic Recombination Telomere Maintenance Telomere Maintenance Via Telomerase DNA Duplex Unwinding DNA Geometric Change Double-strand Break Repair Via Homologous Recombination Recombinational Repair Cell Cycle Mitotic G2 DNA Damage Checkpoint Cell Cycle Process DNA Metabolic Process Mitotic Cell Cycle Process DNA Topological Change RNA-dependent DNA Replication Organelle Organization Double-strand Break Repair Mitotic Cell Cycle DNA Damage Checkpoint Regulation Of Kinase Activity Mitotic Cell Cycle Checkpoint Telomere Maintenance Via Telomere Lengthening Cellular Response To DNA Damage Stimulus Response To Stress Mitotic Cytokinesis Reciprocal Meiotic Recombination Negative Regulation Of Mitotic Cell Cycle Chromosome Segregation Cell Cycle Checkpoint DNA Recombination Positive Regulation Of Transferase Activity Reproduction DNA Repair Regulation Of Protein Phosphorylation Regulation Of Catalytic Activity Regulation Of DNA Recombination Cellular Nitrogen Compound Metabolic Process Activation Of APC-Cdc20 Complex Activity Transcription, RNA-templated Glycine Betaine Biosynthetic Process From Choline Adherens Junction Maintenance Positive Regulation Of Cellular Metabolic Process Cell Proliferation	Neural Plate Formation Serotonin Uptake Lactate Biosynthetic Process From Pyruvate Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Negative Regulation Of Cerebellar Granule Cell Precursor Proliferation Regulation Of Protein Phosphatase Type 2A Activity Quinolinate Biosynthetic Process Negative Regulation Of Synaptic Transmission, Dopaminergic Lactate Biosynthetic Process Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Paraxial Mesoderm Formation Quinolinate Metabolic Process Cellular Response To CGMP Response To CGMP Serotonin Transport Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Sperm Ejaculation Presynaptic Membrane Assembly Neural Plate Morphogenesis L-glutamate Import Presynaptic Membrane Organization Citrulline Metabolic Process Lactate Metabolic Process Urea Cycle Neurotransmitter Uptake Regulation Of Neuron Differentiation Urea Metabolic Process Thalamus Development Striatum Development Paraxial Mesoderm Morphogenesis Neural Plate Development Amino Acid Import Insemination Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter Regulation Of Synaptic Transmission, Dopaminergic Negative Regulation Of DNA-templated Transcription, Elongation Determination Of Adult Lifespan Mitotic Cell Cycle Process Grooming Behavior Regulation Of Neurogenesis Copulation Chromosome Separation Membrane Assembly Subpallium Development Mitotic Cell Cycle Positive Regulation Of Calcium Ion Transmembrane Transporter Activity Monoamine Transport Paraxial Mesoderm Development Membrane Biogenesis L-glutamate Transport
Tagcloud ?			acetylated blocked cdna chip connexin connexin43 cx43 deacetylase diminishment fstl1 giant h4 hdac10 histones interestingly invasion lama4 metastasis mmp modulate modulating pg poorly recognized retarded s100a secreted transfection understood
Tagcloud (Difference) ?			acetylated blocked cdna chip connexin connexin43 cx43 deacetylase diminishment fstl1 giant h4 hdac10 histones interestingly invasion lama4 metastasis mmp modulate modulating pg poorly recognized retarded s100a secreted transfection understood
Tagcloud (Intersection) ?