SYCE1 and RBCK1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SYCE1	RBCK1
Gene Name		synaptonemal complex central element protein 1	RanBP-type and C3HC4-type zinc finger containing 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Central Element	LUBAC Complex
	Molecular Function		Sequence-specific DNA Binding Transcription Factor Activity Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity Ubiquitin Binding
	Biological Process	Synaptonemal Complex Assembly Cell Division	Protein Polyubiquitination Viral Process Negative Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of NF-kappaB Import Into Nucleus Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process T Cell Receptor Signaling Pathway Positive Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Necroptotic Process Protein Linear Polyubiquitination Positive Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		Meiotic synapsis	Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		29 interactors: ALOX5 ARNT2 BFSP2 CCDC102B CCDC53 CINP CYTH3 EDRF1 FAM161A HAUS1 HMG20B HOOK1 HSPB7 IQUB KIFC3 MRFAP1L1 NME7 RBCK1 SCNM1 SKA1 SMARCE1 SPERT SSX2 STX19 TPM1 TPM3 TRAF1 TSG101 ZNF124	46 interactors: APP ARNT2 BACH1 CREBBP IKBKG IREB2 MKRN2 NAA10 NDUFAF3 NEDD4 NR1I2 OTUB2 OTUD6A PAN2 PARK2 PCGF2 PRKCA PSMD4 RNF181 RNF31 SOCS6 SYCE1 TNFAIP3 TRAF1 TRIM21 TRIM25 TRIM65 TRIML1 TSSK3 UBE2D3 UBE2D4 UBE2G1 UBE2K UBE2L3 UBE2L6 UBE2N UBE2S UBE2U UCHL5 UHRF2 USP15 USP2 USP21 USP32 USP49 USP7
Entrez ID		93426	10616
HPRD ID		12598	16643
Ensembl ID		ENSG00000171772	ENSG00000125826
Uniprot IDs		Q8N0S2	A6PVK0 Q9BYM8
PDB IDs			2CRC 2LGY 4DBG
Enriched GO Terms of Interacting Partners?		Organelle Organization Actin-myosin Filament Sliding Muscle Filament Sliding Visual Perception Sensory Perception Of Light Stimulus Cell Division Actin-mediated Cell Contraction Leukotriene Production Involved In Inflammatory Response Positive Regulation Of Heart Rate By Epinephrine	Protein Ubiquitination Protein Modification By Small Protein Conjugation Cellular Protein Modification Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Modification-dependent Protein Catabolic Process Protein Catabolic Process Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Cellular Protein Metabolic Process Cellular Macromolecule Catabolic Process Proteolysis Proteasomal Protein Catabolic Process Protein Metabolic Process Protein Deubiquitination Protein Modification By Small Protein Removal Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Catabolic Process Cellular Metabolic Process Regulation Of Protein Catabolic Process Regulation Of Type I Interferon Production Protein K63-linked Ubiquitination Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Protein K48-linked Ubiquitination Regulation Of Proteasomal Protein Catabolic Process Response To Stress Regulation Of Proteolysis Histone Modification Histone Deubiquitination Cellular Response To Stress Protein K29-linked Ubiquitination Protein K27-linked Ubiquitination Protein K11-linked Ubiquitination Metabolic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Innate Immune Response Chromosome Organization Protein K6-linked Ubiquitination Protein K11-linked Deubiquitination Negative Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Nitrogen Compound Metabolic Process Protein Monoubiquitination Chromatin Modification Protein Autoubiquitination Negative Regulation Of Type I Interferon Production Cellular Process Regulation Of Transcription, DNA-templated
Tagcloud ?		adenocarcinoma adenocarcinomas antigens applications broadens carcinomas complementary concordant ct distinctly expressed family il13ra2 immunotherapeutic lung member members nontumor particular searched spectrum squamous subset testes testis vcx vcx3a xage1	1beta ali allocated attenuates autologous c3hc4 dependently dismutase histology intravenously malondialdehyde mda oalt occluded orthotopic oxidant pathologic peroxiredoxin portal prx ranbp restoring sham sod started u1 uh ul ulinastatin
Tagcloud (Difference) ?		adenocarcinoma adenocarcinomas antigens applications broadens carcinomas complementary concordant ct distinctly expressed family il13ra2 immunotherapeutic lung member members nontumor particular searched spectrum squamous subset testes testis vcx vcx3a xage1	1beta ali allocated attenuates autologous c3hc4 dependently dismutase histology intravenously malondialdehyde mda oalt occluded orthotopic oxidant pathologic peroxiredoxin portal prx ranbp restoring sham sod started u1 uh ul ulinastatin
Tagcloud (Intersection) ?