SYCE1 and MPV17

Number of citations of the paper that reports this interaction (PubMedID 26871637)
43

Data Source:
BioGRID (two hybrid)

		SYCE1	MPV17
Description		synaptonemal complex central element protein 1	mitochondrial inner membrane protein MPV17
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Synaptonemal Complex Central Element Nucleus Chromosome	Cytoplasm Mitochondrion Mitochondrial Inner Membrane Peroxisome Peroxisomal Membrane Cytosol Membrane
	Molecular Function	Protein Binding	Channel Activity
	Biological Process	Synaptonemal Complex Assembly Cell Division Meiotic Cell Cycle Synaptonemal Complex Organization	Glomerular Basement Membrane Development Cellular Response To Reactive Oxygen Species Homeostatic Process Inner Ear Development Transmembrane Transport Regulation Of Mitochondrial DNA Metabolic Process Regulation Of Reactive Oxygen Species Metabolic Process
Pathways		Meiotic synapsis	Peroxisomal protein import Peroxisomal protein import
Drugs
Diseases			Mitochondrial DNA depletion syndrome (MDS)
GWAS
Interacting Genes		45 interacting genes: ALOX5 ARNT2 BEX2 BFSP2 CBY2 CCDC102B CCHCR1 CFAP100 CINP CNN1 EDRF1 EXOC8 FAM161A FAM161B HAUS1 HMG20B HSPB1 HSPB7 IQUB KAT5 KIFC3 KRT18 MBD3 MPV17 MRFAP1L1 NME7 PSTPIP1 RALBP1 RBCK1 RUNX1T1 SCNM1 SKA1 SMARCE1 SPATC1L SSX2 STX19 TFIP11 TPM3 TRAF1 TRIM41 TSG101 TXN2 VPS25 WASHC3 ZNF124	2 interacting genes: PEX5 SYCE1
Entrez ID		93426	4358
HPRD ID		12598	08847
Ensembl ID		ENSG00000171772	ENSG00000115204
Uniprot IDs		A0A0B4J1R9 Q8N0S2	A0A0S2Z3Z9 P39210
PDB IDs
Enriched GO Terms of Interacting Partners?		Cytoskeleton	Protein Import Into Peroxisome Matrix, Translocation Peroxisome Membrane Targeting Sequence Binding Peroxisome Matrix Targeting Signal-1 Binding Peroxisome Targeting Sequence Binding Protein Import Into Peroxisome Matrix, Docking Protein Import Into Peroxisome Membrane Protein Import Into Peroxisome Matrix, Substrate Release Protein Targeting To Peroxisome Protein Import Into Peroxisome Matrix, Receptor Recycling Protein Carrier Chaperone Central Element Protein Unfolding Peroxisomal Membrane Transport Establishment Of Protein Localization To Peroxisome Protein Import Into Peroxisome Matrix Cerebral Cortex Neuron Differentiation Pexophagy Synaptonemal Complex Synaptonemal Complex Assembly Synaptonemal Complex Organization Receptor Recycling Peroxisome Organization Intracellular Protein Transmembrane Transport Cerebral Cortex Cell Migration Positive Regulation Of Multicellular Organism Growth Very Long-chain Fatty Acid Metabolic Process Forebrain Neuron Differentiation Telencephalon Cell Migration Forebrain Cell Migration Receptor Metabolic Process Peroxisomal Matrix Fatty Acid Beta-oxidation Protein Monoubiquitination Chromosome Organization Involved In Meiotic Cell Cycle Endoplasmic Reticulum Organization Peroxisomal Membrane Regulation Of Multicellular Organism Growth Protein Transmembrane Transport Fatty Acid Oxidation Fatty Acid Catabolic Process Lipid Oxidation Protein Tetramerization Cellular Response To Reactive Oxygen Species Neuromuscular Process Mitochondrial Membrane Organization Meiotic Cell Cycle Peroxisome
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