SYCE1 and CNN1

Number of citations of the paper that reports this interaction (PubMedID 27107012)
72

Data Source:
BioGRID (two hybrid)

		SYCE1	CNN1
Description		synaptonemal complex central element protein 1	calponin 1
Image		No pdb structure
GO Annotations	Cellular Component	Synaptonemal Complex Central Element Nucleus Chromosome	Cytoskeleton Focal Adhesion Actin Cytoskeleton
	Molecular Function	Protein Binding	Actin Binding Protein Binding Calmodulin Binding Actin Filament Binding
	Biological Process	Synaptonemal Complex Assembly Cell Division Meiotic Cell Cycle Synaptonemal Complex Organization	Regulation Of Smooth Muscle Contraction Actin Filament Organization Actomyosin Structure Organization Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Pathways		Meiotic synapsis	Developmental Lineage of Mammary Gland Myoepithelial Cells
Drugs
Diseases
GWAS			Presence of antiphospholipid antibodies ( 27098658)
Interacting Genes		45 interacting genes: ALOX5 ARNT2 BEX2 BFSP2 CBY2 CCDC102B CCHCR1 CFAP100 CINP CNN1 EDRF1 EXOC8 FAM161A FAM161B HAUS1 HMG20B HSPB1 HSPB7 IQUB KAT5 KIFC3 KRT18 MBD3 MPV17 MRFAP1L1 NME7 PSTPIP1 RALBP1 RBCK1 RUNX1T1 SCNM1 SKA1 SMARCE1 SPATC1L SSX2 STX19 TFIP11 TPM3 TRAF1 TRIM41 TSG101 TXN2 VPS25 WASHC3 ZNF124	15 interacting genes: ACTA1 ADRB2 CALM1 CCHCR1 COG6 DNMBP FYN MYO1A NCAPD2 PLRG1 PRKCE SYCE1 TFPT TPM3 TUBB
Entrez ID		93426	1264
HPRD ID		12598	02884
Ensembl ID		ENSG00000171772	ENSG00000130176
Uniprot IDs		A0A0B4J1R9 Q8N0S2	B7Z7E1 P51911 Q53FP8 V9HWA5
PDB IDs			1WYP
Enriched GO Terms of Interacting Partners?		Cytoskeleton	Actin Filament Chromosome Organization Innate Immune Response Activating Cell Surface Receptor Signaling Pathway Cell Body Mitotic Chromosome Condensation Cellular Response To Prostaglandin E Stimulus Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc Receptor Mediated Stimulatory Signaling Pathway Cellular Response To Prostaglandin Stimulus Regulation Of Metal Ion Transport Response To Prostaglandin E Mitotic Cell Cycle Protein-containing Complex Binding Regulation Of Calcium Ion Transmembrane Transport Cell Cycle Phase Transition Fc-gamma Receptor Signaling Pathway Condensed Chromosome Regulation Of Systemic Arterial Blood Pressure By Norepinephrine-epinephrine Positive Regulation Of Mini Excitatory Postsynaptic Potential Regulation Of Monoatomic Ion Transport Innate Immune Response-activating Signaling Pathway Cellular Response To Glycine Response To Singlet Oxygen Toll-like Receptor 4 Signaling Pathway Cell Surface Toll-like Receptor Signaling Pathway Chromosome Condensation Cell Division Muscle Contraction Glutamate Receptor Signaling Pathway Cellular Response To Amyloid-beta Activation Of Innate Immune Response Cytoplasm Sarcomere Cellular Response To Oxygen-containing Compound Positive Regulation Of Organelle Organization Modulation Of Chemical Synaptic Transmission Cell Cycle G2/M Phase Transition Regulation Of Calcium Ion Transport Fc Receptor Signaling Pathway Cell Surface Pattern Recognition Receptor Signaling Pathway Chromosome Organization Involved In Meiotic Cell Cycle Response To Amyloid-beta Beta2-adrenergic Receptor Activity Negative Regulation Of High Voltage-gated Calcium Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Immune Response-activating Cell Surface Receptor Signaling Pathway Response To Glycine Ethanol Binding Regulation Of Chromosome Organization Muscle System Process
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