SYCE1 and ALOX5

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SYCE1	ALOX5
Gene Name		synaptonemal complex central element protein 1	arachidonate 5-lipoxygenase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Central Element	Extracellular Space Nuclear Envelope Nuclear Envelope Lumen Cytosol Nuclear Matrix Nuclear Membrane
	Molecular Function		Arachidonate 5-lipoxygenase Activity Iron Ion Binding Protein Binding
	Biological Process	Synaptonemal Complex Assembly Cell Division	Leukotriene Production Involved In Inflammatory Response Leukotriene Metabolic Process Arachidonic Acid Metabolic Process Leukotriene Biosynthetic Process Lipoxygenase Pathway Small Molecule Metabolic Process Oxidation-reduction Process Lipoxin Metabolic Process
Pathways		Meiotic synapsis	Arachidonic acid metabolism Synthesis of 5-eicosatetraenoic acids Metabolism of lipids and lipoproteins Synthesis of Lipoxins (LX) Synthesis of Leukotrienes (LT) and Eoxins (EX)
Drugs			Vitamin E Masoprocol Aminosalicylic Acid Mesalazine Montelukast Diclofenac Diethylcarbamazine Zileuton Sulfasalazine Meclofenamic acid Balsalazide Minocycline Hyperforin Heme
Diseases
GWAS			Mean corpuscular hemoglobin ( 20139978) Mean corpuscular volume ( 20139978)
Protein-Protein Interactions		29 interactors: ALOX5 ARNT2 BFSP2 CCDC102B CCDC53 CINP CYTH3 EDRF1 FAM161A HAUS1 HMG20B HOOK1 HSPB7 IQUB KIFC3 MRFAP1L1 NME7 RBCK1 SCNM1 SKA1 SMARCE1 SPERT SSX2 STX19 TPM1 TPM3 TRAF1 TSG101 ZNF124	17 interactors: ACTB ALOX5AP APP CEP57L1 CEP63 COTL1 DICER1 GRB2 HHIPL2 LTC4S MAD1L1 MAPKAPK2 MEOX1 NUTM1 REL SYCE1 TGFBRAP1
Entrez ID		93426	240
HPRD ID		12598	01065
Ensembl ID		ENSG00000171772	ENSG00000012779
Uniprot IDs		Q8N0S2	E5FPY5 E5FPY8 P09917
PDB IDs			2ABV 3O8Y 3V92 3V98 3V99
Enriched GO Terms of Interacting Partners?		Organelle Organization Actin-myosin Filament Sliding Muscle Filament Sliding Visual Perception Sensory Perception Of Light Stimulus Cell Division Actin-mediated Cell Contraction Leukotriene Production Involved In Inflammatory Response Positive Regulation Of Heart Rate By Epinephrine	Leukotriene Metabolic Process Lipoxin Metabolic Process Arachidonic Acid Metabolic Process Defense Response Lipoxygenase Pathway Icosanoid Metabolic Process Unsaturated Fatty Acid Metabolic Process Long-chain Fatty Acid Metabolic Process Leukotriene Biosynthetic Process Cellular Component Assembly MRNA Stabilization Innate Immune Response Cell Division Immune System Process Platelet Activation Cell Cycle Process Cell Cycle Checkpoint Icosanoid Biosynthetic Process Wound Healing Regulation Of MRNA Stability Unsaturated Fatty Acid Biosynthetic Process Regulation Of RNA Stability Neuron Projection Morphogenesis Conversion Of Ds SiRNA To Ss SiRNA Involved In RNA Interference Regulation Of Metaphase Plate Congression Hair Follicle Cell Proliferation Conversion Of Ds SiRNA To Ss SiRNA Positive Regulation Of Metabolic Process Response To External Stimulus Endocytosis Response To Stress Response To Wounding Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Fatty Acid Metabolic Process Immune Response Microtubule-based Process Regulation Of ERBB Signaling Pathway Regulation Of Enamel Mineralization Peripheral Nervous System Myelin Formation Synaptic Growth At Neuromuscular Junction Zygote Asymmetric Cell Division Spindle Assembly Cell Cycle Neuron Projection Development Signal Transduction In Response To DNA Damage Cell Projection Morphogenesis Vesicle-mediated Transport Targeting Of MRNA For Destruction Involved In RNA Interference Collateral Sprouting In Absence Of Injury Axon Guidance
Tagcloud ?		adenocarcinoma adenocarcinomas antigens applications broadens carcinomas complementary concordant ct distinctly expressed family il13ra2 immunotherapeutic lung member members nontumor particular searched spectrum squamous subset testes testis vcx vcx3a xage1	af4 calcitriol conversely deacetylase derivatives deriving elongation encodes hdac hdac1 hdaci inactive lineage lipoxygenase mll overwrites physiologically portion relieving smad3 smad4 surprisingly switch transcriptionally transforming trichostatin trimethylation tsa
Tagcloud (Difference) ?		adenocarcinoma adenocarcinomas antigens applications broadens carcinomas complementary concordant ct distinctly expressed family il13ra2 immunotherapeutic lung member members nontumor particular searched spectrum squamous subset testes testis vcx vcx3a xage1	af4 calcitriol conversely deacetylase derivatives deriving elongation encodes hdac hdac1 hdaci inactive lineage lipoxygenase mll overwrites physiologically portion relieving smad3 smad4 surprisingly switch transcriptionally transforming trichostatin trimethylation tsa
Tagcloud (Intersection) ?