SYCE1 and CFAP100

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SYCE1	CFAP100
Description		synaptonemal complex central element protein 1	cilia and flagella associated protein 100
Image		No pdb structure
GO Annotations	Cellular Component	Synaptonemal Complex Central Element Nucleus Chromosome	Cytoplasm Cytoskeleton Cilium Motile Cilium Ciliary Basal Body Cell Projection Axonemal Doublet Microtubule
	Molecular Function	Protein Binding	Protein Binding Dynein Complex Binding
	Biological Process	Synaptonemal Complex Assembly Cell Division Meiotic Cell Cycle Synaptonemal Complex Organization	Cilium Movement Inner Dynein Arm Assembly
Pathways		Meiotic synapsis
Drugs
Diseases
GWAS
Interacting Genes		45 interacting genes: ALOX5 ARNT2 BEX2 BFSP2 CBY2 CCDC102B CCHCR1 CFAP100 CINP CNN1 EDRF1 EXOC8 FAM161A FAM161B HAUS1 HMG20B HSPB1 HSPB7 IQUB KAT5 KIFC3 KRT18 MBD3 MPV17 MRFAP1L1 NME7 PSTPIP1 RALBP1 RBCK1 RUNX1T1 SCNM1 SKA1 SMARCE1 SPATC1L SSX2 STX19 TFIP11 TPM3 TRAF1 TRIM41 TSG101 TXN2 VPS25 WASHC3 ZNF124	6 interacting genes: KDM1A RHOU SUV39H1 SUV39H2 SYCE1 TRIM54
Entrez ID		93426	348807
HPRD ID		12598	08805
Ensembl ID		ENSG00000171772	ENSG00000163885
Uniprot IDs		A0A0B4J1R9 Q8N0S2	Q494V2
PDB IDs			8J07
Enriched GO Terms of Interacting Partners?		Cytoskeleton	Histone H3K9 Trimethyltransferase Activity Histone H3K9 Methyltransferase Activity Epigenetic Programming In The Zygotic Pronuclei Histone H3 Methyltransferase Activity Chromosome Epigenetic Programming Of Gene Expression Histone Methyltransferase Activity Epigenetic Regulation Of Gene Expression Cellular Response To Decreased Oxygen Levels Cellular Response To Hypoxia Chromatin Remodeling ENoSc Complex Circadian Rhythm Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity Negative Regulation Of Transcription Initiation-coupled Chromatin Remodeling Chromosome, Centromeric Region Cellular Response To Oxygen Levels Negative Regulation Of Gene Expression, Epigenetic Methyltransferase Activity Protein Demethylase Activity RDNA Heterochromatin MRF Binding Methylation Chromatin Organization Response To Fungicide Guanine Metabolic Process Histone H3K9me2 Methyltransferase Activity RDNA Heterochromatin Formation Regulation Of DNA Repair Histone H3K4 Demethylase Activity Positive Regulation Of Focal Adhesion Disassembly Central Element Regulation Of Transcription By Glucose Rhythmic Process Negative Regulation Of Transcription By RNA Polymerase II Transcription Cis-regulatory Region Binding Histone H3K9 Demethylase Activity Chromatin Silencing Complex Response To Hypoxia Cell Differentiation Positive Regulation Of Cell Size Nuclear Lamina Response To Decreased Oxygen Levels Facultative Heterochromatin Formation DNA Repair Complex Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Response To Oxygen Levels Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of DNA-templated Transcription
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