CHMP4C and STAMBP

Number of citations of the paper that reports this interaction (PubMedID 17711858)
0

Data Source:
BioGRID (pull down)

		CHMP4C	STAMBP
Description		charged multivesicular body protein 4C	STAM binding protein
Image
GO Annotations	Cellular Component	Autophagosome Membrane Kinetochore ESCRT III Complex Nuclear Pore Cytoplasm Lysosomal Membrane Endosome Multivesicular Body Kinetochore Microtubule Cytosol Plasma Membrane Cytoplasmic Side Of Plasma Membrane Membrane Midbody Late Endosome Membrane Multivesicular Body Membrane Flemming Body Amphisome Membrane	Nucleus Nucleoplasm Cytoplasm Endosome Early Endosome Cytosol Plasma Membrane Membrane Cleavage Furrow Extracellular Exosome
	Molecular Function	Protein Binding Protein Homodimerization Activity	Protein Binding Peptidase Activity Metallopeptidase Activity Hydrolase Activity Protein Domain Specific Binding Metal Ion Binding K63-linked Deubiquitinase Activity Deubiquitinase Activity Metal-dependent Deubiquitinase Activity
	Biological Process	Plasma Membrane Repair Vesicle Budding From Membrane Autophagy Nucleus Organization Vacuolar Transport Mitotic Metaphase Chromosome Alignment Regulation Of Centrosome Duplication Protein Transport Macroautophagy Nuclear Membrane Reassembly Negative Regulation Of Cytokinesis Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Mitotic Cytokinesis Checkpoint Signaling Viral Budding From Plasma Membrane Vesicle Fusion With Vacuole Multivesicular Body-lysosome Fusion Midbody Abscission Multivesicular Body Sorting Pathway Membrane Fission Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Autophagosome Maturation Regulation Of Mitotic Spindle Assembly Late Endosome To Lysosome Transport	Mitotic Cytokinesis Proteolysis Cell Surface Receptor Signaling Pathway Via JAK-STAT Positive Regulation Of Cell Population Proliferation Protein Deubiquitination Negative Regulation Of Ras Protein Signal Transduction Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Protein K63-linked Deubiquitination Hippocampal Neuron Apoptotic Process Negative Regulation Of Hippocampal Neuron Apoptotic Process
Pathways		Budding and maturation of HIV virion Macroautophagy Pyroptosis Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex	Metalloprotease DUBs
Drugs
Diseases
GWAS		Age-related hearing impairment ( 34108613) Epithelial ovarian cancer ( 25581431) Ovarian cancer ( 23535730)	Anti-saccade response ( 29064472) Bell's palsy ( 33602968) Blood metabolite levels ( 26401656) Serum metabolite levels ( 23093944 33031748)
Interacting Genes		10 interacting genes: CC2D1A CHMP4A CHMP4B HMGB3P1 PDCD6IP STAMBP TRPC4AP USP54 USP8 VPS4A	51 interacting genes: ALAS1 AMN APOBEC3A ATG14 BMPR1B CASR CHMP1A CHMP1B CHMP2A CHMP3 CHMP4A CHMP4B CHMP4C CHMP5 CLTC CTNNBL1 CYP2C9 DSCR9 EGFR EPS15 GRAP2 GRB2 IL1RL2 ITGA5 MAP2K5 MAP3K2 MLKL NLRP7 NTPCR PJA1 RBM11 RECQL5 RNF11 SMAD2 SMAD6 SMAD7 SNCA SPG7 STAM STAM2 TNFRSF1A TP53 TRAF6 TRIP13 UACA UBC UBE2S ULK1 USP21 USP28 VHL
Entrez ID		92421	10617
HPRD ID		18135	05877
Ensembl ID		ENSG00000164695	ENSG00000124356
Uniprot IDs		Q96CF2	A0A140VK54 A0A804HIF8 A0A804HII8 A0A804HJ64 O95630
PDB IDs		3C3R 5MK3 5V3R 5WA1	2XZE 3RZU 3RZV 5IXF
Enriched GO Terms of Interacting Partners?		Endosome Organization Cytoskeleton-dependent Cytokinesis Mitotic Cytokinetic Process Viral Budding Viral Budding Via Host ESCRT Complex Midbody Abscission Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Multivesicular Body Assembly Multivesicular Body Organization Cytokinetic Process Vesicle Organization Mitotic Metaphase Chromosome Alignment Proteolysis Metaphase Chromosome Alignment Mitotic Cytokinesis Viral Budding From Plasma Membrane K63-linked Deubiquitinase Activity Chromosome Localization Late Endosome To Lysosome Transport Nucleus Organization Regulation Of Mitotic Spindle Assembly Nuclear Membrane Reassembly Viral Release From Host Cell Plasma Membrane Repair Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Spindle Assembly Vesicle Budding From Membrane Viral Process Late Endosome To Vacuole Transport Endosome Macroautophagy Endosome Transport Via Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Organization Membrane Fission Multivesicular Body Sorting Pathway Midbody Nuclear Membrane Organization Autophagosome Maturation Membrane Assembly Nuclear Pore ESCRT III Complex Amphisome Membrane Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Vesicle Fusion With Vacuole Autophagy Multivesicular Body-lysosome Fusion Proteolysis Involved In Protein Catabolic Process Protein Deubiquitination Vesicle Fusion Protein Metabolic Process	ESCRT III Complex Amphisome Membrane Vesicle Fusion With Vacuole Multivesicular Body Organization Multivesicular Body Assembly Multivesicular Body-lysosome Fusion Viral Budding From Plasma Membrane Late Endosome To Vacuole Transport Lysosomal Membrane Organization Endosome Transport Via Multivesicular Body Sorting Pathway Membrane Fission Multivesicular Body Sorting Pathway Late Endosome To Lysosome Transport Kinetochore Microtubule Autophagosome Membrane Viral Budding Via Host ESCRT Complex Regulation Of Mitotic Spindle Assembly Midbody Abscission Regulation Of Mitotic Spindle Organization Viral Budding Nuclear Membrane Reassembly Mitotic Cytokinetic Process Multivesicular Body Membrane Viral Release From Host Cell Plasma Membrane Repair Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Autophagosome Maturation Endosome Organization Regulation Of Spindle Assembly Autophagy Cytokinetic Process Protein-containing Complex Disassembly Endosomal Transport Multivesicular Body Mitotic Metaphase Chromosome Alignment Biological Process Involved In Interaction With Host Nuclear Membrane Organization Vacuolar Transport Vacuole Organization Metaphase Chromosome Alignment Membrane Assembly Endosome Macroautophagy Regulation Of Microtubule Cytoskeleton Organization Chromosome Localization Lysosomal Transport Regulation Of Centrosome Duplication Nuclear Pore Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Nucleus Organization
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