CHMP4C and HMGB3P1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		CHMP4C	HMGB3P1
Description		charged multivesicular body protein 4C	high mobility group box 3 pseudogene 1
Image			No pdb structure
GO Annotations	Cellular Component	Autophagosome Membrane Kinetochore ESCRT III Complex Nuclear Pore Cytoplasm Lysosomal Membrane Endosome Multivesicular Body Kinetochore Microtubule Cytosol Plasma Membrane Cytoplasmic Side Of Plasma Membrane Membrane Midbody Late Endosome Membrane Multivesicular Body Membrane Flemming Body Amphisome Membrane
	Molecular Function	Protein Binding Protein Homodimerization Activity
	Biological Process	Plasma Membrane Repair Vesicle Budding From Membrane Autophagy Nucleus Organization Vacuolar Transport Mitotic Metaphase Chromosome Alignment Regulation Of Centrosome Duplication Protein Transport Macroautophagy Nuclear Membrane Reassembly Negative Regulation Of Cytokinesis Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Mitotic Cytokinesis Checkpoint Signaling Viral Budding From Plasma Membrane Vesicle Fusion With Vacuole Multivesicular Body-lysosome Fusion Midbody Abscission Multivesicular Body Sorting Pathway Membrane Fission Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Autophagosome Maturation Regulation Of Mitotic Spindle Assembly Late Endosome To Lysosome Transport
Pathways		Budding and maturation of HIV virion Macroautophagy Pyroptosis Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex
Drugs
Diseases
GWAS		Age-related hearing impairment ( 34108613) Epithelial ovarian cancer ( 25581431) Ovarian cancer ( 23535730)	Bipolar disorder ( 31043756) Reticulocyte count ( 32888494) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		10 interacting genes: CC2D1A CHMP4A CHMP4B HMGB3P1 PDCD6IP STAMBP TRPC4AP USP54 USP8 VPS4A	2 interacting genes: BANP CHMP4C
Entrez ID		92421	128872
HPRD ID		18135
Ensembl ID		ENSG00000164695
Uniprot IDs		Q96CF2
PDB IDs		3C3R 5MK3 5V3R 5WA1
Enriched GO Terms of Interacting Partners?		Endosome Organization Cytoskeleton-dependent Cytokinesis Mitotic Cytokinetic Process Viral Budding Viral Budding Via Host ESCRT Complex Midbody Abscission Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Multivesicular Body Assembly Multivesicular Body Organization Cytokinetic Process Vesicle Organization Mitotic Metaphase Chromosome Alignment Proteolysis Metaphase Chromosome Alignment Mitotic Cytokinesis Viral Budding From Plasma Membrane K63-linked Deubiquitinase Activity Chromosome Localization Late Endosome To Lysosome Transport Nucleus Organization Regulation Of Mitotic Spindle Assembly Nuclear Membrane Reassembly Viral Release From Host Cell Plasma Membrane Repair Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Spindle Assembly Vesicle Budding From Membrane Viral Process Late Endosome To Vacuole Transport Endosome Macroautophagy Endosome Transport Via Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Organization Membrane Fission Multivesicular Body Sorting Pathway Midbody Nuclear Membrane Organization Autophagosome Maturation Membrane Assembly Nuclear Pore ESCRT III Complex Amphisome Membrane Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Vesicle Fusion With Vacuole Autophagy Multivesicular Body-lysosome Fusion Proteolysis Involved In Protein Catabolic Process Protein Deubiquitination Vesicle Fusion Protein Metabolic Process	Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Plasma Membrane Repair Mitotic Cytokinetic Process ESCRT III Complex Mitotic Cytokinesis Checkpoint Signaling Flemming Body Multivesicular Body Membrane Viral Budding From Plasma Membrane Multivesicular Body Organization Amphisome Membrane Late Endosome To Lysosome Transport Lysosomal Membrane Organization Vesicle Fusion With Vacuole Kinetochore Microtubule Viral Budding Negative Regulation Of Cytokinesis Vesicle Budding From Membrane Nuclear Membrane Reassembly Negative Regulation Of Cell Division Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Assembly Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Viral Release From Host Cell Multivesicular Body Assembly Midbody Abscission Regulation Of Spindle Assembly Multivesicular Body-lysosome Fusion Late Endosome To Vacuole Transport Membrane Fission Regulation Of Mitotic Spindle Organization Regulation Of Centrosome Duplication Nuclear Membrane Organization Endosome Transport Via Multivesicular Body Sorting Pathway Autophagosome Maturation Multivesicular Body Sorting Pathway Multivesicular Body Cytokinetic Process Mitotic Metaphase Chromosome Alignment Autophagosome Membrane Metaphase Chromosome Alignment Membrane Assembly Regulation Of Centrosome Cycle Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle G2/M Phase Transition Chromosome Localization Endosome Organization Nuclear Pore Regulation Of Cytokinesis Nucleus Organization
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