CHMP4C and CHMP4B

Number of citations of the paper that reports this interaction (PMID 14505570)
292

Data Source:
HPRD (two hybrid)

		CHMP4C	CHMP4B
Gene Name		charged multivesicular body protein 4C	charged multivesicular body protein 4B
Image
Gene Ontology Annotations	Cellular Component	Cytosol Midbody Late Endosome Membrane Extracellular Vesicular Exosome Flemming Body	ESCRT III Complex Nucleus Cytoplasm Endosome Cytosol Cytoplasmic Side Of Plasma Membrane Midbody Late Endosome Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Protein Homodimerization Activity	Protein Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Cell Separation After Cytokinesis Nucleus Organization Vacuolar Transport Mitotic Metaphase Plate Congression Abscission Regulation Of Centrosome Duplication Protein Transport Viral Process Endosomal Transport Viral Life Cycle Negative Regulation Of Cytokinesis Regulation Of Viral Process Membrane Organization Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Assembly Positive Regulation Of Viral Release From Host Cell	Cell Separation After Cytokinesis Posttranslational Protein Targeting To Membrane Nucleus Organization Vacuolar Transport Mitotic Metaphase Plate Congression Regulation Of Centrosome Duplication Viral Process Endosomal Transport Viral Life Cycle Maintenance Of Lens Transparency Viral Budding Via Host ESCRT Complex Viral Budding Regulation Of Viral Process Protein Homooligomerization Negative Regulation Of Cell Death Membrane Organization Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Negative Regulation Of Neuron Death Regulation Of Mitotic Spindle Assembly Positive Regulation Of Viral Release From Host Cell Negative Regulation Of Autophagic Vacuole Assembly
Pathways		HIV Life Cycle Budding and maturation of HIV virion HIV Infection Endosomal Sorting Complex Required For Transport (ESCRT) Late Phase of HIV Life Cycle	HIV Life Cycle Budding and maturation of HIV virion HIV Infection Endosomal Sorting Complex Required For Transport (ESCRT) Late Phase of HIV Life Cycle
Drugs
Diseases
GWAS		Ovarian cancer ( 23535730)	Stearic acid (18:0) plasma levels ( 23362303)
Protein-Protein Interactions		10 interactors: CC2D1A CHMP4A CHMP4B HMGB3P1 PDCD6IP STAMBP TRPC4AP USP54 USP8 VPS4A	14 interactors: CHMP1B CHMP3 CHMP4A CHMP4C CHMP5 CHMP6 EXOSC9 HIPK2 PDCD6IP PIAS2 PTPN23 STAMBP UBE2I VPS4A
Entrez ID		92421	128866
HPRD ID		18135	16642
Ensembl ID		ENSG00000164695	ENSG00000101421
Uniprot IDs		Q96CF2	Q9H444
PDB IDs		3C3R	3C3Q 3UM3 4ABM
Enriched GO Terms of Interacting Partners?		Viral Budding Via Host ESCRT Complex Viral Budding Cell Separation After Cytokinesis Virion Assembly Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Cell Division Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Membrane Budding Protein Catabolic Process Mitotic Metaphase Plate Congression Proteolysis Cellular Macromolecule Catabolic Process Metaphase Plate Congression Negative Regulation Of Autophagic Vacuole Assembly Establishment Of Chromosome Localization Viral Life Cycle Vesicle Organization Mitotic Cell Cycle Process Mitotic Sister Chromatid Segregation Posttranslational Protein Targeting To Membrane Mitotic Cell Cycle Sister Chromatid Segregation Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Cytokinesis Negative Regulation Of Macroautophagy Nucleus Organization Catabolic Process Regulation Of Autophagic Vacuole Assembly Cell Cycle Process Regulation Of Vacuole Organization Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Viral Process Negative Regulation Of Neuron Death Endosomal Transport Cell Cycle Negative Regulation Of Autophagy Chromosome Segregation Regulation Of Centrosome Duplication Mitotic Cytokinesis Regulation Of Neuron Death Regulation Of Centrosome Cycle Cellular Protein Metabolic Process Membrane Organization Mitotic Nuclear Division Establishment Of Organelle Localization Positive Regulation Of Exocytosis Vacuolar Transport	Cell Separation After Cytokinesis Cell Division Mitotic Metaphase Plate Congression Metaphase Plate Congression Establishment Of Chromosome Localization Nucleus Organization Vacuolar Transport Mitotic Sister Chromatid Segregation Viral Process Sister Chromatid Segregation Viral Life Cycle Chromosome Segregation Regulation Of Centrosome Duplication Regulation Of Centrosome Cycle Mitotic Nuclear Division Mitotic Cell Cycle Process Endosomal Transport Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Mitotic Cell Cycle Viral Budding Via Host ESCRT Complex Regulation Of Mitotic Spindle Assembly Protein Transport Viral Budding Regulation Of Microtubule Cytoskeleton Organization Establishment Of Organelle Localization Regulation Of Spindle Assembly Establishment Of Protein Localization Cell Cycle Process Regulation Of Microtubule-based Process Regulation Of Mitotic Spindle Organization Organelle Localization Regulation Of Cell Cycle Process Protein Localization Membrane Organization Cell Cycle Virion Assembly Regulation Of Cell Cycle Regulation Of Cellular Component Organization Abscission Cellular Macromolecule Catabolic Process Regulation Of Cytoskeleton Organization Regulation Of Organelle Organization Positive Regulation Of Viral Release From Host Cell Intracellular Transport Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of Cell Division Cellular Protein Catabolic Process Negative Regulation Of Cytokinesis Membrane Budding Organelle Organization
Tagcloud ?		attained conceptually dba deg degs domestication dudeg dudegs ehh eif4a3 foxo3 fst homozygosity horse ideas integrating jeju kegg ontology pony rba reads seq thoroughbred thoroughbreds timeless wgs xp znf592	aculeiform adcc arg58his beaded bfsp1 bfsp2 cataract cerulean connexins coralliform cryaa cryba2 cryba4 crybb1 crybb3 cryga crygb crygc crygd crygs crystallins fasciculiform flaky gja3 gja8 lim2 macedonia pro23thr tmem114
Tagcloud (Difference) ?		attained conceptually dba deg degs domestication dudeg dudegs ehh eif4a3 foxo3 fst homozygosity horse ideas integrating jeju kegg ontology pony rba reads seq thoroughbred thoroughbreds timeless wgs xp znf592	aculeiform adcc arg58his beaded bfsp1 bfsp2 cataract cerulean connexins coralliform cryaa cryba2 cryba4 crybb1 crybb3 cryga crygb crygc crygd crygs crystallins fasciculiform flaky gja3 gja8 lim2 macedonia pro23thr tmem114
Tagcloud (Intersection) ?