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STAMBP and MAP3K2
Number of citations of the paper that reports this interaction (PubMedID
24975362
)
38
Data Source:
BioGRID
(enzymatic study)
STAMBP
MAP3K2
Description
STAM binding protein
mitogen-activated protein kinase kinase kinase 2
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Endosome
Early Endosome
Cytosol
Plasma Membrane
Membrane
Cleavage Furrow
Extracellular Exosome
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Molecular Function
Protein Binding
Peptidase Activity
Metallopeptidase Activity
Hydrolase Activity
Protein Domain Specific Binding
Metal Ion Binding
K63-linked Deubiquitinase Activity
Deubiquitinase Activity
Metal-dependent Deubiquitinase Activity
Nucleotide Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
MAP Kinase Kinase Kinase Activity
Protein Binding
ATP Binding
Kinase Activity
Transferase Activity
Protein Kinase Binding
Metal Ion Binding
Protein Serine Kinase Activity
Biological Process
Mitotic Cytokinesis
Proteolysis
Cell Surface Receptor Signaling Pathway Via JAK-STAT
Positive Regulation Of Cell Population Proliferation
Protein Deubiquitination
Negative Regulation Of Ras Protein Signal Transduction
Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Protein K63-linked Deubiquitination
Hippocampal Neuron Apoptotic Process
Negative Regulation Of Hippocampal Neuron Apoptotic Process
MAPK Cascade
Intracellular Signal Transduction
Cellular Response To Mechanical Stimulus
Pathways
Metalloprotease DUBs
Drugs
Bosutinib
Fostamatinib
Diseases
GWAS
Anti-saccade response (
29064472
)
Bell's palsy (
33602968
)
Blood metabolite levels (
26401656
)
Serum metabolite levels (
23093944
33031748
)
Protein C levels (
28082259
)
Interacting Genes
51 interacting genes:
ALAS1
AMN
APOBEC3A
ATG14
BMPR1B
CASR
CHMP1A
CHMP1B
CHMP2A
CHMP3
CHMP4A
CHMP4B
CHMP4C
CHMP5
CLTC
CTNNBL1
CYP2C9
DSCR9
EGFR
EPS15
GRAP2
GRB2
IL1RL2
ITGA5
MAP2K5
MAP3K2
MLKL
NLRP7
NTPCR
PJA1
RBM11
RECQL5
RNF11
SMAD2
SMAD6
SMAD7
SNCA
SPG7
STAM
STAM2
TNFRSF1A
TP53
TRAF6
TRIP13
UACA
UBC
UBE2S
ULK1
USP21
USP28
VHL
27 interacting genes:
BIRC2
CTNNB1
IKBKG
ITCH
LATS1
MAP2K3
MAP2K4
MAP2K5
MAP2K7
MAP3K5
MAPK8
NEDD4
NFKBIA
PIBF1
PKN2
SH2D2A
SMURF1
SMYD3
STAMBP
STUB1
USP2
WNK1
XIAP
YAP1
YWHAE
YWHAG
YWHAZ
Entrez ID
10617
10746
HPRD ID
05877
10068
Ensembl ID
ENSG00000124356
ENSG00000169967
Uniprot IDs
A0A140VK54
A0A804HIF8
A0A804HII8
A0A804HJ64
O95630
Q9Y2U5
PDB IDs
2XZE
3RZU
3RZV
5IXF
2CU1
2NPT
5EX0
5HQ8
6LDV
6LDW
6LDX
6LDY
Enriched GO Terms of Interacting Partners
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ESCRT III Complex
Amphisome Membrane
Vesicle Fusion With Vacuole
Multivesicular Body Organization
Multivesicular Body Assembly
Multivesicular Body-lysosome Fusion
Viral Budding From Plasma Membrane
Late Endosome To Vacuole Transport
Lysosomal Membrane Organization
Endosome Transport Via Multivesicular Body Sorting Pathway
Membrane Fission
Multivesicular Body Sorting Pathway
Late Endosome To Lysosome Transport
Kinetochore Microtubule
Autophagosome Membrane
Viral Budding Via Host ESCRT Complex
Regulation Of Mitotic Spindle Assembly
Midbody Abscission
Regulation Of Mitotic Spindle Organization
Viral Budding
Nuclear Membrane Reassembly
Mitotic Cytokinetic Process
Multivesicular Body Membrane
Viral Release From Host Cell
Plasma Membrane Repair
Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Autophagosome Maturation
Endosome Organization
Regulation Of Spindle Assembly
Autophagy
Cytokinetic Process
Protein-containing Complex Disassembly
Endosomal Transport
Multivesicular Body
Mitotic Metaphase Chromosome Alignment
Biological Process Involved In Interaction With Host
Nuclear Membrane Organization
Vacuolar Transport
Vacuole Organization
Metaphase Chromosome Alignment
Membrane Assembly
Endosome
Macroautophagy
Regulation Of Microtubule Cytoskeleton Organization
Chromosome Localization
Lysosomal Transport
Regulation Of Centrosome Duplication
Nuclear Pore
Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway
Nucleus Organization
Intracellular Signal Transduction
MAPK Cascade
Regulation Of Signal Transduction
Negative Regulation Of Signal Transduction
Negative Regulation Of Cell Communication
Negative Regulation Of Signaling
Regulation Of Cell Communication
Regulation Of Signaling
Regulation Of Intracellular Signal Transduction
Intracellular Signaling Cassette
Cellular Response To Stress
Signal Transduction
Protein Modification Process
Positive Regulation Of Protein Metabolic Process
Cytosol
Protein Polyubiquitination
Cytoplasm
Regulation Of Apoptotic Process
Negative Regulation Of Intracellular Signal Transduction
Transferase Activity
Regulation Of Programmed Cell Death
Regulation Of Protein Metabolic Process
Post-translational Protein Modification
Protein Serine Kinase Activity
Protein Metabolic Process
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
Cell Surface Receptor Signaling Pathway
MAP Kinase Kinase Activity
Protein Phosphatase Binding
Protein Serine/threonine Kinase Activity
Positive Regulation Of Macromolecule Metabolic Process
Regulation Of Immune Response
Response To Stress
Immune Response-regulating Signaling Pathway
Regulation Of Protein Modification Process
Regulation Of Immune System Process
Positive Regulation Of Signal Transduction
Cellular Senescence
Positive Regulation Of Metabolic Process
Regulation Of Primary Metabolic Process
Protein Domain Specific Binding
Protein Kinase Activity
Stress-activated Protein Kinase Signaling Cascade
Phosphoserine Residue Binding
Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Modification-dependent Protein Catabolic Process
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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