CHMP4C and CC2D1A

Number of citations of the paper that reports this interaction (PMID 16730941)
46

Data Source:
HPRD (two hybrid)

		CHMP4C	CC2D1A
Gene Name		charged multivesicular body protein 4C	coiled-coil and C2 domain containing 1A
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Midbody Late Endosome Membrane Extracellular Vesicular Exosome Flemming Body	Nucleus Cytoplasm Microtubule Organizing Center Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Protein Homodimerization Activity	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Signal Transducer Activity
	Biological Process	Cell Separation After Cytokinesis Nucleus Organization Vacuolar Transport Mitotic Metaphase Plate Congression Abscission Regulation Of Centrosome Duplication Protein Transport Viral Process Endosomal Transport Viral Life Cycle Negative Regulation Of Cytokinesis Regulation Of Viral Process Membrane Organization Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Assembly Positive Regulation Of Viral Release From Host Cell	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Signal Transduction Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Pathways		HIV Life Cycle Budding and maturation of HIV virion HIV Infection Endosomal Sorting Complex Required For Transport (ESCRT) Late Phase of HIV Life Cycle
Drugs
Diseases
GWAS		Ovarian cancer ( 23535730)
Protein-Protein Interactions		10 interactors: CC2D1A CHMP4A CHMP4B HMGB3P1 PDCD6IP STAMBP TRPC4AP USP54 USP8 VPS4A	4 interactors: CDC37 CHMP4A CHMP4C LRP1
Entrez ID		92421	54862
HPRD ID		18135	08616
Ensembl ID		ENSG00000164695	ENSG00000132024
Uniprot IDs		Q96CF2	Q6P1N0
PDB IDs		3C3R
Enriched GO Terms of Interacting Partners?		Viral Budding Via Host ESCRT Complex Viral Budding Cell Separation After Cytokinesis Virion Assembly Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Cell Division Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Membrane Budding Protein Catabolic Process Mitotic Metaphase Plate Congression Proteolysis Cellular Macromolecule Catabolic Process Metaphase Plate Congression Negative Regulation Of Autophagic Vacuole Assembly Establishment Of Chromosome Localization Viral Life Cycle Vesicle Organization Mitotic Cell Cycle Process Mitotic Sister Chromatid Segregation Posttranslational Protein Targeting To Membrane Mitotic Cell Cycle Sister Chromatid Segregation Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Cytokinesis Negative Regulation Of Macroautophagy Nucleus Organization Catabolic Process Regulation Of Autophagic Vacuole Assembly Cell Cycle Process Regulation Of Vacuole Organization Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Viral Process Negative Regulation Of Neuron Death Endosomal Transport Cell Cycle Negative Regulation Of Autophagy Chromosome Segregation Regulation Of Centrosome Duplication Mitotic Cytokinesis Regulation Of Neuron Death Regulation Of Centrosome Cycle Cellular Protein Metabolic Process Membrane Organization Mitotic Nuclear Division Establishment Of Organelle Localization Positive Regulation Of Exocytosis Vacuolar Transport	Cell Separation After Cytokinesis Mitotic Metaphase Plate Congression Metaphase Plate Congression Protein Transport Establishment Of Protein Localization Establishment Of Chromosome Localization Protein Localization Vacuolar Transport Mitotic Sister Chromatid Segregation Sister Chromatid Segregation Nucleus Organization Beta-amyloid Clearance Regulation Of Organelle Organization Viral Life Cycle Endosomal Transport Negative Regulation Of Neuron Death Negative Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway Negative Regulation Of Autophagic Vacuole Assembly Chromosome Segregation Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Neuron Death Abscission Intracellular Transport Mitotic Nuclear Division Viral Budding Via Host ESCRT Complex Establishment Of Organelle Localization Posttranslational Protein Targeting To Membrane Positive Regulation Of Viral Release From Host Cell Regulation Of Mitotic Spindle Assembly Viral Budding Negative Regulation Of Cytokinesis Regulation Of Spindle Assembly Organelle Localization Protein Targeting Cell Division Regulation Of Phospholipase A2 Activity Transport Regulation Of Cellular Component Organization Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Negative Regulation Of Macroautophagy Establishment Of Localization In Cell Regulation Of Mitotic Spindle Organization Regulation Of Cytoskeleton Organization Regulation Of Autophagic Vacuole Assembly Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Negative Regulation Of Smooth Muscle Cell Migration Positive Regulation Of Cholesterol Efflux Regulation Of Vacuole Organization Viral Process Membrane Tubulation
Tagcloud ?		attained conceptually dba deg degs domestication dudeg dudegs ehh eif4a3 foxo3 fst homozygosity horse ideas integrating jeju kegg ontology pony rba reads seq thoroughbred thoroughbreds timeless wgs xp znf592	aki colocalize cooperation defenses elicits endocytic endolysosomes endosomal freud ifn innate interacted knockdown lamp1 linking lysosomal modes modulates operational rab5 resided synergized tape tbk1 termed tlr3 tlr4 trif wave
Tagcloud (Difference) ?		attained conceptually dba deg degs domestication dudeg dudegs ehh eif4a3 foxo3 fst homozygosity horse ideas integrating jeju kegg ontology pony rba reads seq thoroughbred thoroughbreds timeless wgs xp znf592	aki colocalize cooperation defenses elicits endocytic endolysosomes endosomal freud ifn innate interacted knockdown lamp1 linking lysosomal modes modulates operational rab5 resided synergized tape tbk1 termed tlr3 tlr4 trif wave
Tagcloud (Intersection) ?