CHMP4C and TRPC4AP

Number of citations of the paper that reports this interaction (PMID 16730941)
46

Data Source:
HPRD (two hybrid)

		CHMP4C	TRPC4AP
Gene Name		charged multivesicular body protein 4C	transient receptor potential cation channel, subfamily C, member 4 associated protein
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Midbody Late Endosome Membrane Extracellular Vesicular Exosome Flemming Body	Plasma Membrane Cul4A-RING E3 Ubiquitin Ligase Complex
	Molecular Function	Protein Binding Protein Homodimerization Activity	Protein Binding Phosphatase Binding
	Biological Process	Cell Separation After Cytokinesis Nucleus Organization Vacuolar Transport Mitotic Metaphase Plate Congression Abscission Regulation Of Centrosome Duplication Protein Transport Viral Process Endosomal Transport Viral Life Cycle Negative Regulation Of Cytokinesis Regulation Of Viral Process Membrane Organization Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Assembly Positive Regulation Of Viral Release From Host Cell	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Ion Transmembrane Transport Transmembrane Transport Calcium Ion Transmembrane Transport
Pathways		HIV Life Cycle Budding and maturation of HIV virion HIV Infection Endosomal Sorting Complex Required For Transport (ESCRT) Late Phase of HIV Life Cycle	Ion channel transport TRP channels Stimuli-sensing channels
Drugs
Diseases
GWAS		Ovarian cancer ( 23535730)	Prothrombin time ( 22703881)
Protein-Protein Interactions		10 interactors: CC2D1A CHMP4A CHMP4B HMGB3P1 PDCD6IP STAMBP TRPC4AP USP54 USP8 VPS4A	9 interactors: CHMP4C CHUK IKBKB IKBKG RIPK1 TAB1 TNFRSF1A TRADD TRAF2
Entrez ID		92421	26133
HPRD ID		18135	09238
Ensembl ID		ENSG00000164695	ENSG00000100991
Uniprot IDs		Q96CF2	B4E0Q1 E1P5Q0 Q8TEL6
PDB IDs		3C3R
Enriched GO Terms of Interacting Partners?		Viral Budding Via Host ESCRT Complex Viral Budding Cell Separation After Cytokinesis Virion Assembly Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Cell Division Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Membrane Budding Protein Catabolic Process Mitotic Metaphase Plate Congression Proteolysis Cellular Macromolecule Catabolic Process Metaphase Plate Congression Negative Regulation Of Autophagic Vacuole Assembly Establishment Of Chromosome Localization Viral Life Cycle Vesicle Organization Mitotic Cell Cycle Process Mitotic Sister Chromatid Segregation Posttranslational Protein Targeting To Membrane Mitotic Cell Cycle Sister Chromatid Segregation Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Cytokinesis Negative Regulation Of Macroautophagy Nucleus Organization Catabolic Process Regulation Of Autophagic Vacuole Assembly Cell Cycle Process Regulation Of Vacuole Organization Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Viral Process Negative Regulation Of Neuron Death Endosomal Transport Cell Cycle Negative Regulation Of Autophagy Chromosome Segregation Regulation Of Centrosome Duplication Mitotic Cytokinesis Regulation Of Neuron Death Regulation Of Centrosome Cycle Cellular Protein Metabolic Process Membrane Organization Mitotic Nuclear Division Establishment Of Organelle Localization Positive Regulation Of Exocytosis Vacuolar Transport	Positive Regulation Of NF-kappaB Transcription Factor Activity TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 4 Signaling Pathway Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Response To Tumor Necrosis Factor Toll-like Receptor Signaling Pathway Response To Tumor Necrosis Factor Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Activation Of Innate Immune Response I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Innate Immune Response Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Innate Immune Response Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Signal Transduction Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Positive Regulation Of Cytokine Production Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Immune Response-regulating Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Regulation Of Intracellular Signal Transduction MyD88-dependent Toll-like Receptor Signaling Pathway Regulation Of Cytokine Production Positive Regulation Of Type I Interferon Production Cellular Response To Cytokine Stimulus Positive Regulation Of Immune Response Regulation Of Type I Interferon Production Response To Cytokine Defense Response Protein Heterooligomerization Innate Immune Response Positive Regulation Of Cellular Metabolic Process Regulation Of Immune Response Positive Regulation Of Immune System Process Regulation Of Signal Transduction Intracellular Receptor Signaling Pathway Intracellular Signal Transduction Cellular Response To Organic Substance Regulation Of Signaling
Tagcloud ?		attained conceptually dba deg degs domestication dudeg dudegs ehh eif4a3 foxo3 fst homozygosity horse ideas integrating jeju kegg ontology pony rba reads seq thoroughbred thoroughbreds timeless wgs xp znf592
Tagcloud (Difference) ?		attained conceptually dba deg degs domestication dudeg dudegs ehh eif4a3 foxo3 fst homozygosity horse ideas integrating jeju kegg ontology pony rba reads seq thoroughbred thoroughbreds timeless wgs xp znf592
Tagcloud (Intersection) ?