STAMBP and UBE2S

Number of citations of the paper that reports this interaction (PMID 20622874)
46

Data Source:
BioGRID (enzymatic study)

		STAMBP	UBE2S
Gene Name		STAM binding protein	ubiquitin-conjugating enzyme E2S
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Early Endosome Plasma Membrane Cleavage Furrow Extracellular Vesicular Exosome	Anaphase-promoting Complex Cytoplasm
	Molecular Function	Ubiquitin-specific Protease Activity Protein Binding Metallopeptidase Activity Metal Ion Binding	Ubiquitin-protein Transferase Activity ATP Binding Ligase Activity Ubiquitin-like Protein Transferase Activity Ubiquitin Protein Ligase Binding Ubiquitin Protein Ligase Activity Ubiquitin Conjugating Enzyme Activity
	Biological Process	Mitotic Cytokinesis Proteolysis JAK-STAT Cascade Positive Regulation Of Cell Proliferation Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Protein Deubiquitination Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of Ras Protein Signal Transduction	Cellular Protein Modification Process Exit From Mitosis Free Ubiquitin Chain Polymerization Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein K29-linked Ubiquitination Protein K27-linked Ubiquitination Cell Division Activation Of Anaphase-promoting Complex Activity Protein K63-linked Ubiquitination Protein K11-linked Ubiquitination Protein K6-linked Ubiquitination
Pathways			Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		39 interactors: ALAS1 AMN BMPR1B CASR CHMP1A CHMP1B CHMP2A CHMP3 CHMP4A CHMP4B CHMP4C CHMP5 CLTC CTNNBL1 CYP2C9 EPS15 GRAP2 GRB2 ITGA5 MAP2K5 MAP3K2 NTPCR PJA1 RECQL5 RNF11 SMAD2 SMAD6 SMAD7 SPG7 STAM STAM2 TNFRSF1A TRAF6 TRIP13 UACA UBC UBE2S USP21 USP28	29 interactors: ANAPC1 ANAPC11 ANAPC2 ANAPC4 ANAPC5 ANAPC7 APP ATXN3 BIRC2 CDC16 CDC20 CDC23 CDC27 CYLD FZR1 OTUB1 OTUD7B RBCK1 STAMBP UBA1 UBA6 UBC UCHL3 USP15 USP2 USP21 USP5 USP7 ZRANB1
Entrez ID		10617	27338
HPRD ID		05877	15603
Ensembl ID		ENSG00000124356	ENSG00000108106
Uniprot IDs		O95630	Q16763
PDB IDs		2XZE 3RZU 3RZV	1ZDN
Enriched GO Terms of Interacting Partners?		Cell Separation After Cytokinesis Regulation Of Mitotic Spindle Assembly Regulation Of Spindle Assembly Mitotic Metaphase Plate Congression Regulation Of Mitotic Spindle Organization Metaphase Plate Congression Vacuolar Transport Regulation Of Centrosome Duplication Establishment Of Chromosome Localization Endosomal Transport Regulation Of Centrosome Cycle Mitotic Sister Chromatid Segregation Mitotic Nuclear Division Sister Chromatid Segregation Chromosome Segregation Positive Regulation Of Viral Release From Host Cell Nucleus Organization Cell Division Regulation Of Microtubule Cytoskeleton Organization Cell Cycle Process Intracellular Transport Membrane Organization Mitotic Cell Cycle Process Regulation Of Microtubule-based Process Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Viral Process Negative Regulation Of ERBB Signaling Pathway Protein Transport Mitotic Cell Cycle Viral Life Cycle Establishment Of Localization In Cell Establishment Of Protein Localization Regulation Of Mitotic Nuclear Division Regulation Of Protein Complex Assembly Regulation Of Viral Release From Host Cell Cellular Localization Virion Assembly Cell Cycle Enzyme Linked Receptor Protein Signaling Pathway Protein Localization Viral Budding Via Host ESCRT Complex Regulation Of Cellular Component Organization Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Regulation Of Signaling Viral Budding Intracellular Signal Transduction Establishment Of Organelle Localization Regulation Of Cell Cycle Process Regulation Of Cytoskeleton Organization	Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Proteolysis Cellular Macromolecule Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Protein K11-linked Ubiquitination Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Protein Ubiquitination Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Cellular Protein Modification Process Positive Regulation Of Ligase Activity Regulation Of Proteolysis Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-protein Transferase Activity Mitotic Spindle Assembly Checkpoint Positive Regulation Of Protein Ubiquitination Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Spindle Assembly Checkpoint Regulation Of Protein Ubiquitination Cellular Protein Metabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Mitotic Spindle Checkpoint Positive Regulation Of Cellular Protein Catabolic Process Negative Regulation Of Chromosome Segregation Protein Polyubiquitination Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Metaphase/anaphase Transition Spindle Checkpoint Negative Regulation Of Chromosome Organization Positive Regulation Of Proteolysis Positive Regulation Of Protein Catabolic Process Protein Deubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Protein Metabolic Process Protein Modification By Small Protein Removal Protein Ubiquitination Negative Regulation Of Cellular Protein Catabolic Process
Tagcloud ?			arising cluster clusters coexpressed coexpression conjugating coregulated endpoints example examples friendly glados guilt http ie kcnk5 messenger modules online outputs potassium powerful subfamily ucd uncovered user weighted wgcna
Tagcloud (Difference) ?			arising cluster clusters coexpressed coexpression conjugating coregulated endpoints example examples friendly glados guilt http ie kcnk5 messenger modules online outputs potassium powerful subfamily ucd uncovered user weighted wgcna
Tagcloud (Intersection) ?