CRX and PDC

Number of citations of the paper that reports this interaction (PMID 10866677)
18

Data Source:
HPRD (in vitro, two hybrid)

		CRX	PDC
Gene Name		cone-rod homeobox	phosducin
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Transcription Factor Complex	Photoreceptor Outer Segment Photoreceptor Inner Segment Nucleus Cytosol
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Nuclear Hormone Receptor Binding Leucine Zipper Domain Binding	Phospholipase Inhibitor Activity
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Visual Perception Circadian Rhythm Organ Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Photoreceptor Cell Differentiation Response To Stimulus Retina Development In Camera-type Eye	G-protein Coupled Receptor Signaling Pathway Visual Perception Phototransduction Negative Regulation Of Catalytic Activity
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		44 interactors: ABI2 AES ATG12 ATXN7 BANF1 C1orf109 C9orf72 CA8 CCNC CREBBP CSNK1G2-AS1 EIF5A EP300 GCM2 GUCD1 IPO13 KAT2A KIAA0141 KLHL32 LARP4 LONRF1 M1AP MDFI MLLT6 NIP7 NPAS2 NR2E3 NRL OSGIN1 PARK2 PDC PID1 PPP1R16B PRKAB2 PSMB10 QRICH1 RAX2 RBFOX1 ROR2 SFI1 SOX5 STK16 SZT2 UBXN2B	7 interactors: ADRBK1 CAMK2A CRX EIF3I PRKACA PSMC5 YWHAZ
Entrez ID		1406	5132
HPRD ID		03748	01373
Ensembl ID		ENSG00000105392	ENSG00000116703
Uniprot IDs		O43186	P20941 Q52LP8
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Positive Regulation Of Rhodopsin Gene Expression N-terminal Peptidyl-lysine Acetylation Regulation Of Rhodopsin Gene Expression Transcription, DNA-templated Visual Perception Sensory Perception Of Light Stimulus Positive Regulation Of Metabolic Process RNA Biosynthetic Process RNA Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Mitochondrial Fusion Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Cellular Process Organelle Organization Negative Regulation Of Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Autophagy N-terminal Protein Amino Acid Acetylation Nuclear Envelope Reassembly Cellular Response To Stimulus Response To Stimulus Negative Regulation Of Wnt Signaling Pathway Cellular Metabolic Process Somitogenesis Cellular Nitrogen Compound Metabolic Process Developmental Process Nucleobase-containing Compound Metabolic Process Transcription From RNA Polymerase II Promoter Histone Deubiquitination Neurological System Process Somite Development Cellular Response To Stress Regulation Of Type I Interferon Production Peptidyl-amino Acid Modification Peptidyl-lysine Modification Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia	Peptidyl-serine Phosphorylation Positive Regulation Of Transport Regulation Of The Force Of Heart Contraction Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Peptidyl-threonine Phosphorylation Apoptotic Process Activation Of Phospholipase C Activity Programmed Cell Death Regulation Of Cellular Localization Immune System Process Positive Regulation Of Phospholipase C Activity Cell Death Death Positive Regulation Of Cell Cycle Arrest Positive Regulation Of Phospholipase Activity Immune Response Regulation Of Phospholipase Activity Regulation Of Striated Muscle Contraction Positive Regulation Of Lipase Activity Positive Regulation Of Dense Core Granule Biogenesis Negative Regulation Of The Force Of Heart Contraction By Chemical Signal Positive Regulation Of Photoreceptor Cell Differentiation Defense Response Regulation Of Cell Cycle Arrest Regulation Of Apoptotic Process Regulation Of Cell Death Histone H3-T6 Phosphorylation Regulation Of Secretion Regulation Of Signaling Mitotic Cell Cycle Process Mitochondrial Transport Regulation Of Muscle Contraction G1/S Transition Of Mitotic Cell Cycle Epidermal Growth Factor Receptor Signaling Pathway Mitotic Cell Cycle Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Heart Contraction Response To Stress Gene Expression Phosphorylation Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Positive Regulation Of Inclusion Body Assembly Golgi Reassembly Innate Immune Response Cellular Response To Fibroblast Growth Factor Stimulus Intrinsic Apoptotic Signaling Pathway Regulation Of Calcium Ion Transport Response To Fibroblast Growth Factor
Tagcloud ?		5sa aspect cofactor embryos exit hippo lats1 morphogenesis mst1 mst2 neurogenesis orchestrate otx5 phosphorylate photoreceptor pigmentation playing progenitor prolongs remarkably repressing retinal retinogenesis rhodopsin rx1 tead ww yap zebrafish	ascorbate aspartate concerns dicarboxylic dopamine dopaminergic excitotoxicity extracellular glutamate microdialysis mm mpp neurone neurotoxic neurotoxicity output perfused perfusion perfusions phenyl phenylpyridinium protected protective pyrrolidine separated striatal terminals tetrahydropyridine uptake
Tagcloud (Difference) ?		5sa aspect cofactor embryos exit hippo lats1 morphogenesis mst1 mst2 neurogenesis orchestrate otx5 phosphorylate photoreceptor pigmentation playing progenitor prolongs remarkably repressing retinal retinogenesis rhodopsin rx1 tead ww yap zebrafish	ascorbate aspartate concerns dicarboxylic dopamine dopaminergic excitotoxicity extracellular glutamate microdialysis mm mpp neurone neurotoxic neurotoxicity output perfused perfusion perfusions phenyl phenylpyridinium protected protective pyrrolidine separated striatal terminals tetrahydropyridine uptake
Tagcloud (Intersection) ?