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NMI and BRMS1
Number of citations of the paper that reports this interaction (PubMedID
30217970
)
38
Data Source:
BioGRID
(two hybrid, two hybrid)
NMI
BRMS1
Description
N-myc and STAT interactor
BRMS1 transcriptional repressor and anoikis regulator
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Membrane
Nucleus
Nucleoplasm
Cytoplasm
Sin3-type Complex
Molecular Function
Protein Binding
Identical Protein Binding
Protein Binding
Histone Deacetylase Binding
NF-kappaB Binding
Biological Process
Macrophage Activation Involved In Immune Response
Immune System Process
Cell Surface Receptor Signaling Pathway Via JAK-STAT
Negative Regulation Of Cell Population Proliferation
Response To Virus
Negative Regulation Of Type I Interferon Production
Negative Regulation Of Interferon-alpha Production
Negative Regulation Of Interferon-beta Production
Toll-like Receptor 4 Signaling Pathway
Innate Immune Response
Regulation Of Innate Immune Response
Positive Regulation Of Innate Immune Response
Negative Regulation Of Innate Immune Response
Positive Regulation Of Inflammatory Response
Protein K48-linked Ubiquitination
Negative Regulation Of Non-canonical NF-kappaB Signal Transduction
Positive Regulation Of Non-canonical NF-kappaB Signal Transduction
Positive Regulation Of Protein K48-linked Ubiquitination
Negative Regulation Of Transcription By RNA Polymerase II
Apoptotic Process
Regulation Of Gene Expression
Negative Regulation Of Cell Migration
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of NF-kappaB Transcription Factor Activity
Regulation Of Apoptotic Process
Negative Regulation Of DNA-templated Transcription
Positive Regulation Of Protein Deacetylation
Negative Regulation Of Stem Cell Population Maintenance
Positive Regulation Of Stem Cell Population Maintenance
Positive Regulation Of Anoikis
Pathways
SARS-CoV-1 activates/modulates innate immune responses
HDACs deacetylate histones
Potential therapeutics for SARS
Drugs
Diseases
GWAS
Bipolar disorder (
21926972
31043756
)
Interacting Genes
57 interacting genes:
ANKRD13C-DT
BRAT1
BRCA1
BRMS1
C1orf216
CDKN2A
CDKN2D
CNKSR3
CNOT7
COPS7B
CYP2E1
EMILIN1
EXOSC5
GCSH
GOLGA8EP
HDDC3
HGS
HOXC9
HSPA8
HSPH1
IFI35
KDM1A
LCA5L
LSM4
MAD2L1BP
MCPH1
MORF4L1
MTMR6
MTMR9
MYC
MYCN
MYOM3
NECAP2
POMZP3
PSMA1
RYBP
SCEL
SFR1
SH3GLB2
SINHCAF
SNAPC5
SOX10
STAT1
STAT3
STAT4
STAT5A
STAT5B
STAT6
THAP8
TRAF5
TRIM72
TRIP12
TUBA3C
TUBA3E
TXLNA
TXLNB
UBE2I
50 interacting genes:
ANGPTL4
APP
ARID4A
BEX2
BRMS1L
CEP70
CSNK2A1
CYTOR
DIRAS3
DNAJB1
DNAJB6
E2F1
EEF1A1
EP300
GOLGB1
HDAC1
HDAC2
HDAC3
HDAC4
HDAC5
HDAC6
HSP90AA1
HSPA4
IL13RA2
ING1
KLK9
KPNA5
LRIF1
LYPD3
MCRS1
MRC2
NMI
PFDN5
PSMC3IP
RBBP4
RBBP7
RBP1
RELA
SAP30
SIN3A
SMARCE1
SMTN
SNAI1
SNX6
SPOP
SRC
SUDS3
TAF1
THRSP
UBE2D1
Entrez ID
9111
25855
HPRD ID
04632
05879
Ensembl ID
ENSG00000123609
ENSG00000174744
Uniprot IDs
Q13287
G5E9I4
Q9HCU9
PDB IDs
2XUS
4AUV
Enriched GO Terms of Interacting Partners
?
Nucleoplasm
Cell Surface Receptor Signaling Pathway Via JAK-STAT
Growth Hormone Receptor Signaling Pathway Via JAK-STAT
Cell Surface Receptor Signaling Pathway Via STAT
Growth Hormone Receptor Signaling Pathway
Interleukin-9-mediated Signaling Pathway
Negative Regulation Of Signal Transduction
Negative Regulation Of Cell Communication
Negative Regulation Of Signaling
Regulation Of Cell Population Proliferation
RNA Polymerase II Transcription Regulator Complex
Negative Regulation Of RNA Metabolic Process
Negative Regulation Of Developmental Process
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Nucleic Acid Metabolic Process
Regulation Of Programmed Cell Death
Regulation Of Erythrocyte Differentiation
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Cell Population Proliferation
Development Of Secondary Female Sexual Characteristics
Development Of Secondary Male Sexual Characteristics
DNA-binding Transcription Factor Binding
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Sin3-type Complex
Regulation Of Apoptotic Process
Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Metabolic Process
Negative Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
DNA-binding Transcription Factor Activity
Positive Regulation Of RNA Metabolic Process
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Cell Differentiation
DNA-templated Transcription
Positive Regulation Of Mesenchymal Cell Proliferation
Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Biosynthetic Process
Regulation Of Transcription By RNA Polymerase II
Mitotic Cell Cycle
Negative Regulation Of Biosynthetic Process
Positive Regulation Of Macromolecule Metabolic Process
Development Of Secondary Sexual Characteristics
Positive Regulation Of Gene Expression
Regulation Of Myeloid Cell Apoptotic Process
Positive Regulation Of Metabolic Process
Sin3-type Complex
Negative Regulation Of Stem Cell Population Maintenance
Positive Regulation Of Stem Cell Population Maintenance
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of DNA-templated Transcription
Histone Deacetylase Complex
Negative Regulation Of RNA Metabolic Process
Negative Regulation Of Biosynthetic Process
Regulation Of Stem Cell Population Maintenance
Negative Regulation Of Metabolic Process
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Macromolecule Biosynthetic Process
Chromatin Organization
Negative Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Histone Deacetylase Activity
Regulation Of Primary Metabolic Process
Histone Deacetylase Activity, Hydrolytic Mechanism
Histone Deacetylase Binding
Chromatin Remodeling
Protein Lysine Deacetylase Activity
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Regulation Of Metabolic Process
Regulation Of Cellular Response To Growth Factor Stimulus
Regulation Of RNA Metabolic Process
Epigenetic Regulation Of Gene Expression
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Macromolecule Metabolic Process
Regulation Of Gene Expression
Negative Regulation Of Signal Transduction
Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Signaling
Negative Regulation Of Cell Communication
Negative Regulation Of Locomotion
Negative Regulation Of Developmental Process
Nucleus
Nucleoplasm
Positive Regulation Of Developmental Process
Negative Regulation Of Cell Migration
Positive Regulation Of Multicellular Organismal Process
Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Cell Motility
Negative Regulation Of Multicellular Organismal Process
Regulation Of Protein Metabolic Process
Protein-containing Complex
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