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NMI and TRIP12
Number of citations of the paper that reports this interaction (PubMedID
23034180
)
53
Data Source:
BioGRID
(affinity chromatography technology, affinity chromatography technology, pull down)
NMI
TRIP12
Description
N-myc and STAT interactor
thyroid hormone receptor interactor 12
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Membrane
Nucleus
Nucleoplasm
Cytosol
Nuclear Speck
Molecular Function
Protein Binding
Identical Protein Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Transferase Activity
Nuclear Thyroid Hormone Receptor Binding
Ubiquitin Protein Ligase Activity
Biological Process
Macrophage Activation Involved In Immune Response
Immune System Process
Cell Surface Receptor Signaling Pathway Via JAK-STAT
Negative Regulation Of Cell Population Proliferation
Response To Virus
Negative Regulation Of Type I Interferon Production
Negative Regulation Of Interferon-alpha Production
Negative Regulation Of Interferon-beta Production
Toll-like Receptor 4 Signaling Pathway
Innate Immune Response
Regulation Of Innate Immune Response
Positive Regulation Of Innate Immune Response
Negative Regulation Of Innate Immune Response
Positive Regulation Of Inflammatory Response
Protein K48-linked Ubiquitination
Negative Regulation Of Non-canonical NF-kappaB Signal Transduction
Positive Regulation Of Non-canonical NF-kappaB Signal Transduction
Positive Regulation Of Protein K48-linked Ubiquitination
Protein Polyubiquitination
DNA Repair
Ubiquitin-dependent Protein Catabolic Process
DNA Damage Response
Protein Ubiquitination
Heterochromatin Boundary Formation
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Regulation Of Embryonic Development
DNA Repair-dependent Chromatin Remodeling
Pathways
SARS-CoV-1 activates/modulates innate immune responses
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Carotid intima media thickness x smoking interaction (
32117412
)
Estimated glomerular filtration rate (
31015462
31152163
)
Metabolite levels (
23823483
)
Systolic blood pressure (
30224653
)
Weight (
28552196
)
Interacting Genes
57 interacting genes:
ANKRD13C-DT
BRAT1
BRCA1
BRMS1
C1orf216
CDKN2A
CDKN2D
CNKSR3
CNOT7
COPS7B
CYP2E1
EMILIN1
EXOSC5
GCSH
GOLGA8EP
HDDC3
HGS
HOXC9
HSPA8
HSPH1
IFI35
KDM1A
LCA5L
LSM4
MAD2L1BP
MCPH1
MORF4L1
MTMR6
MTMR9
MYC
MYCN
MYOM3
NECAP2
POMZP3
PSMA1
RYBP
SCEL
SFR1
SH3GLB2
SINHCAF
SNAPC5
SOX10
STAT1
STAT3
STAT4
STAT5A
STAT5B
STAT6
THAP8
TRAF5
TRIM72
TRIP12
TUBA3C
TUBA3E
TXLNA
TXLNB
UBE2I
31 interacting genes:
ATF7IP
CARNS1
CDKN2A
CELSR3
CLSTN1
CUL2
DSCR9
ERG
FBXW7
GBA1
LCOR
MTNR1A
MTNR1B
MYC
NAE1
NMI
NRIP1
OGT
PARP1
PTF1A
SMAD4
SMAD9
SOX6
SRPK2
TAF10
THRB
UBC
UBE2D1
UBE2D2
UBE2L3
UBE4B
Entrez ID
9111
9320
HPRD ID
04632
05144
Ensembl ID
ENSG00000123609
ENSG00000153827
Uniprot IDs
Q13287
A0A6Q8PGG9
A0A6Q8PHK0
A0A994J4J0
A0A994J569
A0A994J755
H7C1L9
Q14669
PDB IDs
9BKR
9BKS
Enriched GO Terms of Interacting Partners
?
Nucleoplasm
Cell Surface Receptor Signaling Pathway Via JAK-STAT
Growth Hormone Receptor Signaling Pathway Via JAK-STAT
Cell Surface Receptor Signaling Pathway Via STAT
Growth Hormone Receptor Signaling Pathway
Interleukin-9-mediated Signaling Pathway
Negative Regulation Of Signal Transduction
Negative Regulation Of Cell Communication
Negative Regulation Of Signaling
Regulation Of Cell Population Proliferation
RNA Polymerase II Transcription Regulator Complex
Negative Regulation Of RNA Metabolic Process
Negative Regulation Of Developmental Process
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Nucleic Acid Metabolic Process
Regulation Of Programmed Cell Death
Regulation Of Erythrocyte Differentiation
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Cell Population Proliferation
Development Of Secondary Female Sexual Characteristics
Development Of Secondary Male Sexual Characteristics
DNA-binding Transcription Factor Binding
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Sin3-type Complex
Regulation Of Apoptotic Process
Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Metabolic Process
Negative Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
DNA-binding Transcription Factor Activity
Positive Regulation Of RNA Metabolic Process
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Cell Differentiation
DNA-templated Transcription
Positive Regulation Of Mesenchymal Cell Proliferation
Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Biosynthetic Process
Regulation Of Transcription By RNA Polymerase II
Mitotic Cell Cycle
Negative Regulation Of Biosynthetic Process
Positive Regulation Of Macromolecule Metabolic Process
Development Of Secondary Sexual Characteristics
Positive Regulation Of Gene Expression
Regulation Of Myeloid Cell Apoptotic Process
Positive Regulation Of Metabolic Process
Protein Modification Process
Positive Regulation Of Macromolecule Metabolic Process
Nuclear Estrogen Receptor Binding
Nucleoplasm
Positive Regulation Of RNA Biosynthetic Process
Ubiquitin Protein Ligase Binding
Post-translational Protein Modification
Positive Regulation Of RNA Metabolic Process
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of Transcription By RNA Polymerase II
Protein Modification By Small Protein Conjugation
Protein Ubiquitination
Modification-dependent Protein Catabolic Process
Regulation Of Transcription By RNA Polymerase II
Regulation Of Protein Ubiquitination
Proteolysis Involved In Protein Catabolic Process
Positive Regulation Of Metabolic Process
Regulation Of RNA Metabolic Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Proteolysis
Positive Regulation Of Post-translational Protein Modification
Regulation Of Post-translational Protein Modification
Regulation Of Neuron Apoptotic Process
Regulation Of DNA-templated Transcription
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of RNA Biosynthetic Process
Protein-containing Complex
Ubiquitin-dependent Protein Catabolic Process
Nucleus
Negative Regulation Of DNA-templated Transcription
DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Macromolecule Biosynthetic Process
Protein Polyubiquitination
Cell Cycle Phase Transition
Positive Regulation Of Macromolecule Biosynthetic Process
Protein Metabolic Process
Chromatin
Regulation Of Nucleobase-containing Compound Metabolic Process
Transcription By RNA Polymerase II
Negative Regulation Of Biosynthetic Process
G1/S Transition Of Mitotic Cell Cycle
Cell Cycle G1/S Phase Transition
Regulation Of Gene Expression
Positive Regulation Of Biosynthetic Process
Melatonin Receptor Activity
Negative Regulation Of RNA Metabolic Process
Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Multicellular Organismal Process
Macromolecule Metabolic Process
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