NMI and ANKRD13C-DT

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid, affinity chromatography technology, two hybrid)
HPRD (two hybrid)

		NMI	ANKRD13C-DT
Description		N-myc and STAT interactor	ANKRD13C divergent transcript
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Nucleoplasm Cytoplasm Cytosol Membrane
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding
	Biological Process	Macrophage Activation Involved In Immune Response Immune System Process Cell Surface Receptor Signaling Pathway Via JAK-STAT Negative Regulation Of Cell Population Proliferation Response To Virus Negative Regulation Of Type I Interferon Production Negative Regulation Of Interferon-alpha Production Negative Regulation Of Interferon-beta Production Toll-like Receptor 4 Signaling Pathway Innate Immune Response Regulation Of Innate Immune Response Positive Regulation Of Innate Immune Response Negative Regulation Of Innate Immune Response Positive Regulation Of Inflammatory Response Protein K48-linked Ubiquitination Negative Regulation Of Non-canonical NF-kappaB Signal Transduction Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Positive Regulation Of Protein K48-linked Ubiquitination
Pathways		SARS-CoV-1 activates/modulates innate immune responses
Drugs
Diseases
GWAS
Interacting Genes		57 interacting genes: ANKRD13C-DT BRAT1 BRCA1 BRMS1 C1orf216 CDKN2A CDKN2D CNKSR3 CNOT7 COPS7B CYP2E1 EMILIN1 EXOSC5 GCSH GOLGA8EP HDDC3 HGS HOXC9 HSPA8 HSPH1 IFI35 KDM1A LCA5L LSM4 MAD2L1BP MCPH1 MORF4L1 MTMR6 MTMR9 MYC MYCN MYOM3 NECAP2 POMZP3 PSMA1 RYBP SCEL SFR1 SH3GLB2 SINHCAF SNAPC5 SOX10 STAT1 STAT3 STAT4 STAT5A STAT5B STAT6 THAP8 TRAF5 TRIM72 TRIP12 TUBA3C TUBA3E TXLNA TXLNB UBE2I	3 interacting genes: FLNA MDFI NMI
Entrez ID		9111	11147
HPRD ID		04632	05083
Ensembl ID		ENSG00000123609	ENSG00000197568
Uniprot IDs		Q13287
PDB IDs
Enriched GO Terms of Interacting Partners?		Nucleoplasm Cell Surface Receptor Signaling Pathway Via JAK-STAT Growth Hormone Receptor Signaling Pathway Via JAK-STAT Cell Surface Receptor Signaling Pathway Via STAT Growth Hormone Receptor Signaling Pathway Interleukin-9-mediated Signaling Pathway Negative Regulation Of Signal Transduction Negative Regulation Of Cell Communication Negative Regulation Of Signaling Regulation Of Cell Population Proliferation RNA Polymerase II Transcription Regulator Complex Negative Regulation Of RNA Metabolic Process Negative Regulation Of Developmental Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Nucleic Acid Metabolic Process Regulation Of Programmed Cell Death Regulation Of Erythrocyte Differentiation Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Cell Population Proliferation Development Of Secondary Female Sexual Characteristics Development Of Secondary Male Sexual Characteristics DNA-binding Transcription Factor Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Sin3-type Complex Regulation Of Apoptotic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process DNA-binding Transcription Factor Activity Positive Regulation Of RNA Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Cell Differentiation DNA-templated Transcription Positive Regulation Of Mesenchymal Cell Proliferation Regulation Of Macromolecule Metabolic Process Positive Regulation Of Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Mitotic Cell Cycle Negative Regulation Of Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process Development Of Secondary Sexual Characteristics Positive Regulation Of Gene Expression Regulation Of Myeloid Cell Apoptotic Process Positive Regulation Of Metabolic Process	Protein Sequestering Activity Regulation Of Membrane Repolarization During Atrial Cardiac Muscle Cell Action Potential Fc-gamma Receptor I Complex Binding Formation Of Radial Glial Scaffolds Tubulin Deacetylation Myb Complex Establishment Of Sertoli Cell Barrier Negative Regulation Of Interferon-alpha Production Positive Regulation Of Protein K48-linked Ubiquitination Glycoprotein Ib-IX-V Complex Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Protein Localization To Bicellular Tight Junction Regulation Of Protein K48-linked Ubiquitination Regulation Of Atrial Cardiac Muscle Cell Membrane Repolarization Regulation Of Membrane Repolarization During Cardiac Muscle Cell Action Potential Blood Coagulation, Intrinsic Pathway Regulation Of Membrane Repolarization During Action Potential Regulation Of Intracellular Signal Transduction Positive Regulation Of Integrin-mediated Signaling Pathway Apical Dendrite Positive Regulation Of Neuron Migration Negative Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Platelet Activation Actin Crosslink Formation Negative Regulation Of Transcription By RNA Polymerase I Protein Deacetylation Negative Regulation Of Biosynthetic Process Sertoli Cell Development Dorsal/ventral Axis Specification Trophoblast Giant Cell Differentiation Negative Regulation Of Interferon-beta Production Protein Localization To Cell-cell Junction Protein Activation Cascade Negative Regulation Of Macromolecule Metabolic Process Macrophage Activation Involved In Immune Response Positive Regulation Of Protein Polyubiquitination Megakaryocyte Development Regulation Of Integrin-mediated Signaling Pathway G Protein-coupled Dopamine Receptor Signaling Pathway Cell Differentiation Involved In Embryonic Placenta Development Negative Regulation Of Metabolic Process Macromolecule Deacylation Positive Regulation Of Potassium Ion Transmembrane Transport Cortical Cytoskeleton Wound Healing, Spreading Of Cells Protein Localization To Cell Surface Regulation Of Protein Polyubiquitination Regulation Of Signal Transduction Positive Regulation Of Potassium Ion Transport Negative Regulation Of Non-canonical NF-kappaB Signal Transduction
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