ANXA3

Name	annexin A3
Structure
Novel Interactors	1 novel interactors: BAG5
Interactors	6 interactors: EMG1 IGSF21 REG3A TP53 UBR1 UNC119
GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Vesicle Membrane Membrane Phagocytic Vesicle Membrane Specific Granule Extracellular Exosome
	Molecular Function	Phosphatidylserine Binding Phospholipase Inhibitor Activity Calcium Ion Binding Calcium-dependent Phospholipid Binding Phospholipase A2 Inhibitor Activity Calcium-dependent Protein Binding
	Biological Process	Phagocytosis Positive Regulation Of Endothelial Cell Migration Defense Response To Bacterium Neutrophil Degranulation Positive Regulation Of Angiogenesis Positive Regulation Of DNA-binding Transcription Factor Activity
Pathways	Developmental Lineage of Pancreatic Ductal Cells
Drugs	Fluocinolone acetonide Ethanolamine Difluocortolone
GWAS	Amyotrophic lateral sclerosis (sporadic) ( 24529757 ) Daytime nap ( 33568662 ) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514 ) Metabolite levels ( 23823483 ) Non-albumin protein levels ( 22558069 ) Refractive error ( 32231278 ) Rheumatoid arthritis ( 22446963 30423114 )
Entrez ID	306
HPRD ID	00111
Ensembl ID	ENSG00000138772
Uniprot IDs	P12429
PDB IDs	1AII 1AXN
GO Terms Enriched among Interactors ?	Response To Symbiotic Bacterium Response To Symbiont Positive Regulation Of Detection Of Glucose Protein-folding Chaperone Binding Oligodendrocyte Apoptotic Process Negative Regulation Of Fermentation Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia Histone Deacetylase Regulator Activity Negative Regulation Of Pentose-phosphate Shunt Positive Regulation Of Thymocyte Apoptotic Process Positive Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly Response To Actinomycin D T Cell Proliferation Involved In Immune Response Negative Regulation Of Helicase Activity Oxidative Stress-induced Premature Senescence Negative Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate Negative Regulation Of G1 To G0 Transition Regulation Of G1 To G0 Transition Glucose Catabolic Process To Lactate Via Pyruvate Negative Regulation Of Proteolysis Glial Cell Apoptotic Process Cellular Response To UV-C Germ Cell Nucleus Cellular Response To Actinomycin D ATP-dependent DNA/DNA Annealing Activity Negative Regulation Of Caveolin-mediated Endocytosis Negative Regulation Of Clathrin-dependent Endocytosis Negative Regulation Of Protein Refolding Negative Regulation Of Protein Folding RRNA (pseudouridine) Methyltransferase Activity Nucleologenesis Ubiquitin-dependent Protein Catabolic Process Via The N-end Rule Pathway Negative Regulation Of Cellular Component Organization B Cell Lineage Commitment Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Pentose-phosphate Shunt Junctional Membrane Complex Nucleolus Organization Mitochondrial DNA Repair Bone Marrow Development Stress-induced Premature Senescence Regulation Of Caveolin-mediated Endocytosis L-leucine Binding