CLDN1 and TJP2

Number of citations of the paper that reports this interaction (PMID 10601346)
178

Data Source:
HPRD (in vitro)

		CLDN1	TJP2
Gene Name		claudin 1	tight junction protein 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Plasma Membrane Tight Junction Integral Component Of Membrane Apical Plasma Membrane Lateral Plasma Membrane	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Adherens Junction Tight Junction Cell Junction
	Molecular Function	Structural Molecule Activity Protein Binding Identical Protein Binding	Guanylate Kinase Activity Protein Binding Protein C-terminus Binding Protein Domain Specific Binding Protein Binding, Bridging
	Biological Process	Cell Adhesion Viral Process Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Cell-cell Junction Organization Establishment Of Skin Barrier	Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Response To Organic Substance Hippo Signaling Nucleotide Phosphorylation Intestinal Absorption Establishment Of Endothelial Intestinal Barrier Regulation Of Membrane Permeability
Pathways		Cell junction organization Cell-cell junction organization Tight junction interactions	Apoptotic cleavage of cell adhesion proteins Apoptotic cleavage of cellular proteins Signaling by Hippo Programmed Cell Death Apoptotic execution phase
Drugs
Diseases
GWAS		Working memory ( 21107309)	Refractive error ( 23396134) Renal sinus fat ( 22044751)
Protein-Protein Interactions		12 interactors: BRD4 CLDN3 DRG1 INADL LNX1 MMP14 MMP2 MPDZ TJP1 TJP2 TJP3 WNK4	15 interactors: CDK6 CGN CLDN1 CLDN2 CTNNA1 EPB41 HGS OCLN SAFB SCRIB SH3KBP1 TJP1 YWHAB YWHAG YWHAZ
Entrez ID		9076	9414
HPRD ID		04760	06369
Ensembl ID		ENSG00000163347	ENSG00000119139
Uniprot IDs		A5JSJ9 O95832	B7Z2R3 B7Z954 Q9UDY2
PDB IDs			2OSG 3E17
Enriched GO Terms of Interacting Partners?		Establishment Of Endothelial Intestinal Barrier Response To Hypoxia Anatomical Structure Development Establishment Of Endothelial Barrier Hippo Signaling Tissue Development Epithelium Development Response To Abiotic Stimulus Epithelial Cell Development Endodermal Cell Differentiation Regulation Of Cell Cycle Checkpoint Developmental Process Endothelial Cell Development Endoderm Formation Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Collagen Catabolic Process Cell-cell Signaling Involved In Cell-cell Junction Organization Execution Phase Of Apoptosis Collagen Metabolic Process Endothelial Cell Differentiation Multicellular Organismal Macromolecule Metabolic Process Endoderm Development Multicellular Organismal Metabolic Process Endothelium Development Extracellular Matrix Disassembly Regulation Of Phosphorylation Of RNA Polymerase II C-terminal Domain Blastocyst Development Cell Development Intracellular Signal Transduction Distal Tubule Morphogenesis Cell-cell Junction Assembly Regulation Of Cell Cycle Process Embryo Development Formation Of Primary Germ Layer Negative Regulation Of DNA Damage Checkpoint Renal Sodium Ion Absorption Response To Magnetism Histone H3-K14 Acetylation Epithelial Cell Differentiation Negative Regulation Of Pancreatic Juice Secretion Renal Sodium Ion Transport Myelination Axon Ensheathment Positive Regulation Of Spindle Checkpoint Cell Differentiation Multicellular Organismal Development Astrocyte Cell Migration Gastrulation Histone H4-K12 Acetylation Intramembranous Ossification	Cell-cell Junction Organization Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Cell-cell Junction Assembly Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Apoptotic Process Programmed Cell Death Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Cell Death Death Cell Junction Assembly Positive Regulation Of Apoptotic Signaling Pathway Apical Junction Assembly Positive Regulation Of Mitochondrion Organization Epithelial Cell Development Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Regulation Of Mitochondrion Organization Signaling Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Cell Communication Protein Targeting Membrane Organization Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Hippo Signaling Enzyme Linked Receptor Protein Signaling Pathway Intrinsic Apoptotic Signaling Pathway Signal Transduction Epithelial Cell Differentiation Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Tight Junction Assembly Positive Regulation Of Intracellular Transport Negative Regulation Of ERBB Signaling Pathway Cell Development Cell Adhesion Cellular Component Assembly Protein Localization Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell-cell Signaling Involved In Cell-cell Junction Organization Cell Dedifferentiation Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Regulation Of Signal Transduction Positive Regulation Of Transport Cellular Protein Localization Execution Phase Of Apoptosis Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Apoptotic Signaling Pathway Negative Regulation Of Integrin-mediated Signaling Pathway
Tagcloud ?		aldh1a1 anxa1 bcar1 crmp1 endpoint folr1 foxm1 il12rb2 il7r inconclusive kiaa1524 lox mcm7 mta1 mtdh ncoa3 ndrg2 nedd9 nes overview pbk ppm1d principally prognostication qualifying slc7a5 sqstm1 warranted wnt1
Tagcloud (Difference) ?		aldh1a1 anxa1 bcar1 crmp1 endpoint folr1 foxm1 il12rb2 il7r inconclusive kiaa1524 lox mcm7 mta1 mtdh ncoa3 ndrg2 nedd9 nes overview pbk ppm1d principally prognostication qualifying slc7a5 sqstm1 warranted wnt1
Tagcloud (Intersection) ?