CLDN1 and BRD4

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		CLDN1	BRD4
Gene Name		claudin 1	bromodomain containing 4
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Plasma Membrane Tight Junction Integral Component Of Membrane Apical Plasma Membrane Lateral Plasma Membrane	Nuclear Chromatin Condensed Nuclear Chromosome Nucleus Nucleoplasm Chromosome Cytoplasm Positive Transcription Elongation Factor Complex B
	Molecular Function	Structural Molecule Activity Protein Binding Identical Protein Binding	P53 Binding DNA Binding Chromatin Binding Protein Binding Lysine-acetylated Histone Binding
	Biological Process	Cell Adhesion Viral Process Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Cell-cell Junction Organization Establishment Of Skin Barrier	Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Inner Cell Mass Cell Proliferation Chromatin Remodeling Transcription, DNA-templated Protein Phosphorylation Cellular Response To DNA Damage Stimulus Chromosome Segregation Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Viral Process Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of DNA Binding Histone H4-K12 Acetylation Histone H3-K14 Acetylation Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Inflammatory Response Regulation Of Phosphorylation Of RNA Polymerase II C-terminal Domain Negative Regulation Of DNA Damage Checkpoint
Pathways		Cell junction organization Cell-cell junction organization Tight junction interactions
Drugs
Diseases
GWAS		Working memory ( 21107309)
Protein-Protein Interactions		12 interactors: BRD4 CLDN3 DRG1 INADL LNX1 MMP14 MMP2 MPDZ TJP1 TJP2 TJP3 WNK4	18 interactors: C7orf25 C8orf33 CCNT1 CCNT2 CHFR CLDN1 HIST2H3C HIST2H4A HIST4H4 JMJD6 MESDC2 PRPF40A RFC1 RFC2 RFC3 RFC4 RFC5 TCERG1
Entrez ID		9076	23476
HPRD ID		04760	10574
Ensembl ID		ENSG00000163347	ENSG00000141867
Uniprot IDs		A5JSJ9 O95832	O60885
PDB IDs			2I8N 2LSP 2NNU 2OSS 2OUO 2YEL 2YEM 3MXF 3P5O 3SVF 3SVG 3U5J 3U5K 3U5L 3UVW 3UVX 3UVY 3UW9 3ZYU 4A9L 4BJX 4BW1 4BW2 4BW3 4BW4 4C66 4C67 4DON 4E96 4F3I 4GPJ 4HBV 4HBW 4HBX 4HBY 4HXK 4HXL 4HXM 4HXN 4HXO 4HXP 4HXR 4HXS 4IOO 4IOQ 4IOR 4J0R 4J0S 4KV1 4KV4 4LR6 4LRG 4MEN 4MEO 4MEP 4MEQ
Enriched GO Terms of Interacting Partners?		Establishment Of Endothelial Intestinal Barrier Response To Hypoxia Anatomical Structure Development Establishment Of Endothelial Barrier Hippo Signaling Tissue Development Epithelium Development Response To Abiotic Stimulus Epithelial Cell Development Endodermal Cell Differentiation Regulation Of Cell Cycle Checkpoint Developmental Process Endothelial Cell Development Endoderm Formation Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Collagen Catabolic Process Cell-cell Signaling Involved In Cell-cell Junction Organization Execution Phase Of Apoptosis Collagen Metabolic Process Endothelial Cell Differentiation Multicellular Organismal Macromolecule Metabolic Process Endoderm Development Multicellular Organismal Metabolic Process Endothelium Development Extracellular Matrix Disassembly Regulation Of Phosphorylation Of RNA Polymerase II C-terminal Domain Blastocyst Development Cell Development Intracellular Signal Transduction Distal Tubule Morphogenesis Cell-cell Junction Assembly Regulation Of Cell Cycle Process Embryo Development Formation Of Primary Germ Layer Negative Regulation Of DNA Damage Checkpoint Renal Sodium Ion Absorption Response To Magnetism Histone H3-K14 Acetylation Epithelial Cell Differentiation Negative Regulation Of Pancreatic Juice Secretion Renal Sodium Ion Transport Myelination Axon Ensheathment Positive Regulation Of Spindle Checkpoint Cell Differentiation Multicellular Organismal Development Astrocyte Cell Migration Gastrulation Histone H4-K12 Acetylation Intramembranous Ossification	Telomere Maintenance Nucleotide-excision Repair, DNA Gap Filling Telomere Maintenance Via Semi-conservative Replication Nuclear DNA Replication Telomere Maintenance Via Recombination Mitotic Recombination DNA Strand Elongation Involved In DNA Replication DNA Strand Elongation Telomere Maintenance Via Telomere Lengthening Transcription-coupled Nucleotide-excision Repair Cell Cycle Nucleotide-excision Repair DNA-dependent DNA Replication Mitotic Cell Cycle Homeostatic Process DNA Methylation On Cytosine Chromosome Organization DNA Metabolic Process Nucleobase-containing Compound Metabolic Process Chromatin Silencing At RDNA Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process DNA Recombination Cellular Nitrogen Compound Metabolic Process DNA Replication Nitrogen Compound Metabolic Process Chromatin Silencing Histone Demethylation Protein Demethylation Histone H4-K20 Demethylation Negative Regulation Of Megakaryocyte Differentiation Organelle Organization DNA Methylation Demethylation Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Hematopoietic Progenitor Cell Differentiation DNA Replication-dependent Nucleosome Assembly DNA Modification Cellular Metabolic Process DNA Repair Cell Cycle Process Gene Silencing Cellular Homeostasis Regulation Of Megakaryocyte Differentiation Gene Expression Cell Division CENP-A Containing Nucleosome Assembly Cellular Macromolecule Biosynthetic Process Cellular Response To DNA Damage Stimulus Macromolecule Biosynthetic Process
Tagcloud ?		aldh1a1 anxa1 bcar1 crmp1 endpoint folr1 foxm1 il12rb2 il7r inconclusive kiaa1524 lox mcm7 mta1 mtdh ncoa3 ndrg2 nedd9 nes overview pbk ppm1d principally prognostication qualifying slc7a5 sqstm1 warranted wnt1	3d chip combining compensatory confirming consequently deprived downregulate driver enrichment estrogens everolimus feedback jq1 loops lted matrigel mediating mimic mtor myc ofmycby oncogenes otherwise resensitization signatures uncover upregulation xenograft
Tagcloud (Difference) ?		aldh1a1 anxa1 bcar1 crmp1 endpoint folr1 foxm1 il12rb2 il7r inconclusive kiaa1524 lox mcm7 mta1 mtdh ncoa3 ndrg2 nedd9 nes overview pbk ppm1d principally prognostication qualifying slc7a5 sqstm1 warranted wnt1	3d chip combining compensatory confirming consequently deprived downregulate driver enrichment estrogens everolimus feedback jq1 loops lted matrigel mediating mimic mtor myc ofmycby oncogenes otherwise resensitization signatures uncover upregulation xenograft
Tagcloud (Intersection) ?