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CLDN1 and TJP1
Number of citations of the paper that reports this interaction (PubMedID
10601346
)
52
Data Source:
HPRD
(in vitro)
CLDN1
TJP1
Description
claudin 1
tight junction protein 1
Image
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Cell-cell Junction
Bicellular Tight Junction
Membrane
Basolateral Plasma Membrane
Apical Plasma Membrane
Lateral Plasma Membrane
Cell Junction
Protein-containing Complex
Tight Junction
Anchoring Junction
Podosome
Cytoplasm
Cytosol
Plasma Membrane
Adherens Junction
Gap Junction
Bicellular Tight Junction
Membrane
Basolateral Plasma Membrane
Cell Junction
Protein-containing Complex
Cell Projection
Apical Junction Complex
Apical Part Of Cell
Tight Junction
Anchoring Junction
Molecular Function
Virus Receptor Activity
Structural Molecule Activity
Protein Binding
Identical Protein Binding
Protein Binding
Calmodulin Binding
Cadherin Binding
Cell Adhesion Molecule Binding
Biological Process
Cell Adhesion
Establishment Of Blood-nerve Barrier
Response To Toxic Substance
Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules
Positive Regulation Of Cell Migration
Response To Lipopolysaccharide
Cell Junction Maintenance
Maintenance Of Blood-brain Barrier
Cell-cell Junction Organization
Response To Ethanol
Symbiont Entry Into Host Cell
Protein Complex Oligomerization
Positive Regulation Of Epithelial Cell Proliferation Involved In Wound Healing
Establishment Of Skin Barrier
Xenobiotic Transport Across Blood-nerve Barrier
Response To Interleukin-18
Bicellular Tight Junction Assembly
Cellular Response To Lead Ion
Cellular Response To Type II Interferon
Cellular Response To Tumor Necrosis Factor
Response To Dexamethasone
Cellular Response To Transforming Growth Factor Beta Stimulus
Positive Regulation Of Wound Healing
Establishment Of Endothelial Intestinal Barrier
Liver Regeneration
Positive Regulation Of Bicellular Tight Junction Assembly
Cellular Response To Butyrate
Cell-cell Junction Assembly
Positive Regulation Of Cell Population Proliferation
Actin Cytoskeleton Organization
Positive Regulation Of Cell Migration
Actomyosin Structure Organization
Adherens Junction Maintenance
Maintenance Of Blood-brain Barrier
Ameloblast Differentiation
Negative Regulation Of Apoptotic Process
Cell-cell Junction Organization
Regulation Of Cytoskeleton Organization
Negative Regulation Of Stress Fiber Assembly
Protein Localization To Adherens Junction
Establishment Of Endothelial Intestinal Barrier
Cell-cell Adhesion
Protein Localization To Cell-cell Junction
Regulation Of Cell Junction Assembly
Protein Localization To Bicellular Tight Junction
Positive Regulation Of Sprouting Angiogenesis
Positive Regulation Of Blood-brain Barrier Permeability
Positive Regulation Of Cell-cell Adhesion Mediated By Cadherin
Regulation Of Bicellular Tight Junction Assembly
Pathways
Tight junction interactions
Regulation of gap junction activity
Regulation of gap junction activity
Signaling by Hippo
Apoptotic cleavage of cell adhesion proteins
RUNX1 regulates expression of components of tight junctions
SARS-CoV-2 targets PDZ proteins in cell-cell junction
SARS-CoV-2 targets PDZ proteins in cell-cell junction
Drugs
Diseases
Neonatal ichthyosis-sclerosing cholangitis (NISCH) syndrome; Ichthyosis, leukocyte vacuoles, alopecia, and sclerosing cholangitis (ILVASC)
GWAS
Optic disc size (
31809533
)
Response to antipsychotic treatment in schizophrenia (working memory) (
21107309
)
Central corneal thickness (
29760442
30894546
31798171
32528159
)
Corneal structure (
23291589
)
Response to antipsychotic treatment (
23241943
)
Spleen volume (
34128465
)
Interacting Genes
18 interacting genes:
BRD4
CD69
CD79A
CLDN3
DRG1
FNDC9
LNX1
MMP14
MMP2
MPDZ
MS4A3
PATJ
TJP1
TJP2
TJP3
TMEM179B
TMEM9
WNK4
40 interacting genes:
ACTA1
ACTN4
AFDN
ARVCF
CGN
CLDN1
CLDN16
CLDN2
CLDN3
CLDN4
CLDN5
CLDN6
CLDN7
CLDN8
CNKSR2
CTNNA1
CTTN
EGFR
F11R
GJA1
GJA3
GJA8
GJB3
GJC1
GJD3
GRIN1
GRIN2D
HSP90AA1
JAM2
JAM3
KHDRBS1
KIRREL1
PEA15
PTPN14
TJP2
TJP3
TRPC4
TTC3
UBN1
YBX3
Entrez ID
9076
7082
HPRD ID
04760
03002
Ensembl ID
ENSG00000163347
ENSG00000104067
Uniprot IDs
A5JSJ9
O95832
A0A087X0K9
A0A0G2JNH2
A0A7I2V5U5
A9CQZ8
B4DZK4
G3V1L9
G5E9E7
Q07157
PDB IDs
2H2B
2H2C
2H3M
2JWE
2KXR
2KXS
2RCZ
3CYY
3LH5
3SHU
3SHW
3TSV
3TSW
3TSZ
4OEO
4OEP
4Q2Q
4YYX
Enriched GO Terms of Interacting Partners
?
Bicellular Tight Junction
Tight Junction
Positive Regulation Of Blood-brain Barrier Permeability
Cell-cell Junction Organization
Maintenance Of Blood-brain Barrier
Establishment Of Endothelial Barrier
Anchoring Junction
Endothelial Cell Development
Regulation Of Blood-brain Barrier Permeability
Cell Junction Organization
Establishment Of Endothelial Intestinal Barrier
Positive Regulation Of Vascular Permeability
Protein Localization To Cell-cell Junction
Apical Junction Complex
Cell-cell Junction Assembly
Epithelial Cell Development
Regulation Of Vascular Permeability
Tight Junction Assembly
Membrane
Tight Junction Organization
Anatomical Structure Homeostasis
Tissue Homeostasis
Protein Localization To Cell Junction
Apical Part Of Cell
Multicellular Organismal-level Homeostasis
Cell Adhesion Molecule Binding
Cell Junction Assembly
Vascular Process In Circulatory System
Cell-cell Junction Maintenance
Apicolateral Plasma Membrane
Circulatory System Process
Plasma Membrane
Regulation Of T-helper 17 Cell Differentiation
Endodermal Cell Differentiation
Regulation Of T-helper 17 Type Immune Response
Collagen Catabolic Process
Regulation Of Cell Adhesion
Regulation Of Cell Fate Commitment
Ovarian Follicle Development
Extracellular Matrix Disassembly
Cellular Response To Genistein
Negative Regulation Of GDF15-GFRAL Signaling Pathway
Cell Junction
Histone H4K8ac Reader Activity
Aldosterone Secretion
Regulation Of T-helper Cell Differentiation
Cell Junction Maintenance
Regulation Of Lymphocyte Differentiation
Homeostatic Process
Transmembrane Signaling Receptor Activity
Anchoring Junction
Bicellular Tight Junction
Cell-cell Junction Organization
Tight Junction
Cell-cell Junction Assembly
Cell Junction Organization
Cell Junction Assembly
Cell-cell Adhesion
Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules
Cell-cell Junction
Bicellular Tight Junction Assembly
Cell Junction
Tight Junction Assembly
Maintenance Of Blood-brain Barrier
Tight Junction Organization
Cell Adhesion
Plasma Membrane
Apicolateral Plasma Membrane
Connexin Complex
Gap Junction Channel Activity
Structural Molecule Activity
Anatomical Structure Homeostasis
Tissue Homeostasis
Gap Junction
Establishment Of Endothelial Intestinal Barrier
Establishment Of Endothelial Barrier
Endothelial Cell Development
Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules
Gap Junction Assembly
Cadherin Binding
Cell-cell Contact Zone
Lateral Plasma Membrane
Cell Development
Cellular Component Assembly
Multicellular Organismal-level Homeostasis
Paracellular Transport
System Process
Epithelial Cell Development
Cell-cell Signaling
Identical Protein Binding
Intercellular Transport
Basolateral Plasma Membrane
Signaling
Cell Communication
Membrane
Intercalated Disc
Regulation Of Locomotion
Homeostatic Process
Cell Communication By Electrical Coupling Involved In Cardiac Conduction
Developmental Process
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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