SNRPB and PRMT7

Number of citations of the paper that reports this interaction (PMID 17709427)
33

Data Source:
BioGRID (pull down)

		SNRPB	PRMT7
Gene Name		small nuclear ribonucleoprotein polypeptides B and B1	protein arginine methyltransferase 7
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex U7 SnRNP U1 SnRNP U4 SnRNP U12-type Spliceosomal Complex Cytosol Small Nuclear Ribonucleoprotein Complex Methylosome SMN-Sm Protein Complex Extracellular Vesicular Exosome Catalytic Step 2 Spliceosome Histone Pre-mRNA 3'end Processing Complex	Nucleus Nucleoplasm Nucleolus Cytosol Plasma Membrane
	Molecular Function	Protein Binding Poly(A) RNA Binding Histone Pre-mRNA DCP Binding	Histone-arginine N-methyltransferase Activity S-adenosylmethionine-dependent Methyltransferase Activity [myelin Basic Protein]-arginine N-methyltransferase Activity Protein-arginine Omega-N Monomethyltransferase Activity Protein-arginine Omega-N Asymmetric Methyltransferase Activity Protein-arginine Omega-N Symmetric Methyltransferase Activity Histone Binding Ribonucleoprotein Complex Binding Histone Methyltransferase Activity (H4-R3 Specific)
	Biological Process	Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription Histone MRNA Metabolic Process RNA Splicing Gene Expression MRNA 3'-end Processing NcRNA Metabolic Process	Spliceosomal SnRNP Assembly Chromatin Organization Regulation Of Gene Expression By Genetic Imprinting Transcription, DNA-templated Regulation Of Transcription, DNA-templated Histone Methylation Peptidyl-arginine Methylation Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Cell Differentiation Histone Arginine Methylation DNA Methylation Involved In Gamete Generation Regulation Of Protein Binding Histone H4-R3 Methylation
Pathways		mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Metabolism of non-coding RNA mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway Cleavage of Growing Transcript in the Termination Region SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs snRNP Assembly Processing of Capped Intronless Pre-mRNA SLBP independent Processing of Histone Pre-mRNAs RNA Polymerase II Transcription Termination	Chromatin modifying enzymes Chromatin organization RMTs methylate histone arginines
Drugs
Diseases
GWAS			Magnesium levels ( 20700443)
Protein-Protein Interactions		48 interactors: ASCC2 BANP C14orf1 CALCOCO2 CD2BP2 CDKN2A CEP55 CLNS1A COIL CTDP1 DAB1 DDX20 DHX9 FNBP4 GEMIN4 GEMIN5 GEMIN6 GEMIN7 GIGYF2 GOLGA2 IL7R KRT40 L3MBTL3 LSM11 LSM2 LSM8 PNMA1 PRMT5 PRMT7 PSMA3 RBPMS RFX6 SKIV2L SMN1 SMN2 SMNDC1 SNRPD1 SNRPD3 SNUPN SS18L1 STRAP STXBP2 STXBP3 TFIP11 TOP3B TRIM23 WBP4 WDR77	10 interactors: CTCFL DIO3 H3F3C HIST1H3A HIST1H4A HIST2H2AC MNDA POT1 SNRPB ZBTB24
Entrez ID		6628	54496
HPRD ID		01655	15174
Ensembl ID		ENSG00000125835	ENSG00000132600
Uniprot IDs		P14678 Q66K91	Q9NVM4
PDB IDs		1D3B 2Y9A 2Y9B 2Y9C 2Y9D 3CW1 3PGW
Enriched GO Terms of Interacting Partners?		Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing MRNA Processing RNA Processing MRNA Metabolic Process Ribonucleoprotein Complex Assembly Ribonucleoprotein Complex Biogenesis Gene Expression RNA Metabolic Process Cellular Macromolecular Complex Assembly Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process NcRNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Component Assembly Spliceosomal Complex Assembly Cellular Metabolic Process Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine Neutrophil Degranulation Chromosome Organization Histone H4-R3 Methylation Neutrophil Activation Involved In Immune Response Peptidyl-arginine N-methylation Chromatin Organization Spliceosomal Tri-snRNP Complex Assembly Metabolic Process Histone Arginine Methylation Peptidyl-arginine Methylation Regulation Of Mitotic Cell Cycle Phase Transition Transcription, DNA-templated Neutrophil Mediated Immunity Histone MRNA Metabolic Process Chromatin Modification Neutrophil Activation Regulation Of Cell Cycle Phase Transition Regulation Of Mitotic Cell Cycle Cellular Process RNA Biosynthetic Process Regulation Of T Cell Differentiation In Thymus Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Cell Cycle Process Pancreatic Epsilon Cell Differentiation Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration SnRNA Import Into Nucleus Spliceosomal Complex Disassembly	DNA Methylation DNA Modification DNA Replication-dependent Nucleosome Assembly DNA Methylation On Cytosine Chromatin Silencing At RDNA Regulation Of Gene Expression, Epigenetic Cellular Aromatic Compound Metabolic Process Chromatin Silencing Cellular Nitrogen Compound Metabolic Process DNA Conformation Change Nitrogen Compound Metabolic Process Telomere Maintenance Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of DNA Strand Elongation Chromosome Organization Methylation DNA Metabolic Process Nucleobase-containing Compound Metabolic Process Gene Silencing Thyroid Hormone Catabolic Process Heterocycle Metabolic Process Nucleosome Assembly Gene Expression Telomere Formation Via Telomerase Histone H4-K20 Demethylation Chromatin Assembly Nucleosome Organization Chromatin Assembly Or Disassembly Cellular Macromolecular Complex Assembly Negative Regulation Of Megakaryocyte Differentiation Protein-DNA Complex Assembly Positive Regulation Of Helicase Activity Telomere Capping Negative Regulation Of Telomere Maintenance Via Telomerase DNA Packaging Chromatin Organization Positive Regulation Of Telomerase Activity Telomere Assembly Positive Regulation Of Telomere Maintenance Via Telomerase Hormone Catabolic Process Regulation Of Chromosome Organization Positive Regulation Of Growth Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Negative Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Positive Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Cellular Component Assembly Regulation Of Telomerase Activity
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