MBD2 and HINFP

Number of citations of the paper that reports this interaction (PMID 11553631)
17

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		MBD2	HINFP
Gene Name		methyl-CpG binding domain protein 2	histone H4 transcription factor
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Histone Deacetylase Complex Nuclear Chromatin Heterochromatin Nucleus Nucleoplasm Cytoplasm Protein Complex	Nucleus Nucleoplasm Nucleolus Cajal Body
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Satellite DNA Binding MRNA Binding Protein Binding Methyl-CpG Binding Protein Domain Specific Binding Nucleosomal DNA Binding SiRNA Binding C2H2 Zinc Finger Domain Binding	DNA Binding Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Protein Binding Enzyme Binding Histone Binding Transcription Regulatory Region DNA Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Gene Expression Positive Regulation Of Wnt Signaling Pathway Regulation Of Gene Expression, Epigenetic Regulation Of Cell Proliferation Maternal Behavior ATP-dependent Chromatin Remodeling Cellular Protein Complex Assembly Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Transcription, DNA-templated	DNA Damage Checkpoint G1/S Transition Of Mitotic Cell Cycle Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle In Utero Embryonic Development DNA Repair Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Establishment Of Protein Localization Myoblast Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated
Pathways		NoRC negatively regulates rRNA expression RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription RNA Polymerase I Promoter Clearance Epigenetic regulation of gene expression Negative epigenetic regulation of rRNA expression RNA Polymerase I Promoter Opening
Drugs
Diseases
GWAS
Protein-Protein Interactions		14 interactors: CREBBP DHX9 GATAD2A GATAD2B GPN1 HDAC1 HDAC2 HINFP LAMTOR3 MBD3 MBD3L1 MBD3L2 RBBP4 SIN3A	25 interactors: ATN1 CDYL2 EFTUD2 ELP4 GSPT1 JUND MBD2 MDC1 MIF4GD MKI67 MORF4L1 NIPBL NPDC1 POM121C PRRC2C RBM17 RBM26 RPUSD4 TLE3 TRA2B TRAF2 TRIM44 TTF2 U2AF1 ZNHIT1
Entrez ID		8932	25988
HPRD ID		04647	07387
Ensembl ID		ENSG00000134046
Uniprot IDs		Q9UBB5	Q9BQA5
PDB IDs		2L2L
Enriched GO Terms of Interacting Partners?		ATP-dependent Chromatin Remodeling Negative Regulation Of Gene Expression, Epigenetic Regulation Of Gene Expression, Epigenetic Chromatin Modification Chromosome Organization Transcription, DNA-templated RNA Metabolic Process RNA Biosynthetic Process Chromatin Organization Chromatin Remodeling Gene Expression Negative Regulation Of Gene Expression Rhythmic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Embryo Development Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Histone Modification Macromolecule Biosynthetic Process Regulation Of Gene Expression Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Histone Deacetylation Cellular Response To Heat Protein Deacetylation Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Embryonic Digit Morphogenesis Fungiform Papilla Formation Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Fungiform Papilla Morphogenesis Positive Regulation Of Receptor Biosynthetic Process Fungiform Papilla Development Eyelid Development In Camera-type Eye Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Hair Follicle Placode Formation Response To Heat Tongue Morphogenesis Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Receptor Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Histone H4 Deacetylation	RNA Metabolic Process MRNA Metabolic Process Nucleobase-containing Compound Metabolic Process MRNA Processing Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Cellular Nitrogen Compound Metabolic Process RNA Processing RNA Splicing Nitrogen Compound Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of Histone Deacetylation Termination Of RNA Polymerase II Transcription Regulation Of Gene Expression Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Regulation Of Protein Deacetylation RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Histone H4 Acetylation Regulation Of RNA Metabolic Process ATP-dependent Chromatin Remodeling Pharynx Development DNA-templated Transcription, Termination Chromatin Modification Chromosome Organization Double-strand Break Repair Via Homologous Recombination Recombinational Repair External Genitalia Morphogenesis Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Transcription, DNA-templated Negative Regulation Of RNA Biosynthetic Process Maintenance Of Mitotic Sister Chromatid Cohesion Uterus Morphogenesis Gall Bladder Development Negative Regulation Of G0 To G1 Transition Regulation Of Nucleic Acid-templated Transcription Cellular Macromolecule Biosynthetic Process Positive Regulation Of Ossification Regulation Of RNA Biosynthetic Process Chromatin Organization Macromolecule Biosynthetic Process Histone Acetylation Cellular Response To X-ray MRNA Transport Internal Peptidyl-lysine Acetylation
Tagcloud ?		additionally adipose closely cpg deacetylases detailed dio dnmts epigenetic fatty feedback h3k4 h4 hdacs histones hypoacetylated hypomethylated island leptin maintain methyltransferases modification modifications obese obesity pol polyunsaturated pufas serve	acta2 amscs architectural cd105 cd73 cd90 chondrogenic confluence confluent cyto eng fibroblastic nes npat nt5e pou5f1 renewing rnaseq sfrp2 sfrp4 successively thy1 versatility wisp2 wnt2 wnt2b wnt5a wnt5b wnt7b
Tagcloud (Difference) ?		additionally adipose closely cpg deacetylases detailed dio dnmts epigenetic fatty feedback h3k4 h4 hdacs histones hypoacetylated hypomethylated island leptin maintain methyltransferases modification modifications obese obesity pol polyunsaturated pufas serve	acta2 amscs architectural cd105 cd73 cd90 chondrogenic confluence confluent cyto eng fibroblastic nes npat nt5e pou5f1 renewing rnaseq sfrp2 sfrp4 successively thy1 versatility wisp2 wnt2 wnt2b wnt5a wnt5b wnt7b
Tagcloud (Intersection) ?