HINFP and GSPT1

Number of citations of the paper that reports this interaction (PMID 17577209)
8

Data Source:
BioGRID (two hybrid)

		HINFP	GSPT1
Gene Name		histone H4 transcription factor	G1 to S phase transition 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cajal Body	Intracellular
	Molecular Function	DNA Binding Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Protein Binding Enzyme Binding Histone Binding Transcription Regulatory Region DNA Binding Metal Ion Binding	Translation Release Factor Activity GTPase Activity Protein Binding GTP Binding Poly(A) RNA Binding
	Biological Process	DNA Damage Checkpoint G1/S Transition Of Mitotic Cell Cycle Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle In Utero Embryonic Development DNA Repair Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Establishment Of Protein Localization Myoblast Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated	G1/S Transition Of Mitotic Cell Cycle Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translational Termination Protein Methylation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		25 interactors: ATN1 CDYL2 EFTUD2 ELP4 GSPT1 JUND MBD2 MDC1 MIF4GD MKI67 MORF4L1 NIPBL NPDC1 POM121C PRRC2C RBM17 RBM26 RPUSD4 TLE3 TRA2B TRAF2 TRIM44 TTF2 U2AF1 ZNHIT1	10 interactors: ATXN1 BIRC2 BIRC3 CDKN2A ETF1 GSPT2 HINFP PABPC1 PIK3R1 XIAP
Entrez ID		25988	2935
HPRD ID		07387	00753
Ensembl ID			ENSG00000103342
Uniprot IDs		Q9BQA5	B2RCT6 P15170 Q7KZX8
PDB IDs			3E1Y 3KUI
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process MRNA Metabolic Process Nucleobase-containing Compound Metabolic Process MRNA Processing Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Cellular Nitrogen Compound Metabolic Process RNA Processing RNA Splicing Nitrogen Compound Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of Histone Deacetylation Termination Of RNA Polymerase II Transcription Regulation Of Gene Expression Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Regulation Of Protein Deacetylation RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Histone H4 Acetylation Regulation Of RNA Metabolic Process ATP-dependent Chromatin Remodeling Pharynx Development DNA-templated Transcription, Termination Chromatin Modification Chromosome Organization Double-strand Break Repair Via Homologous Recombination Recombinational Repair External Genitalia Morphogenesis Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Transcription, DNA-templated Negative Regulation Of RNA Biosynthetic Process Maintenance Of Mitotic Sister Chromatid Cohesion Uterus Morphogenesis Gall Bladder Development Negative Regulation Of G0 To G1 Transition Regulation Of Nucleic Acid-templated Transcription Cellular Macromolecule Biosynthetic Process Positive Regulation Of Ossification Regulation Of RNA Biosynthetic Process Chromatin Organization Macromolecule Biosynthetic Process Histone Acetylation Cellular Response To X-ray MRNA Transport Internal Peptidyl-lysine Acetylation	Inhibition Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Positive Regulation Of Cellular Metabolic Process Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Protein Ubiquitination Regulation Of Cysteine-type Endopeptidase Activity Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Positive Regulation Of Metabolic Process Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Negative Regulation Of Necroptotic Process Negative Regulation Of Necrotic Cell Death Regulation Of Endopeptidase Activity Regulation Of RIG-I Signaling Pathway Regulation Of Necroptotic Process Regulation Of Peptidase Activity Positive Regulation Of Protein Ubiquitination Apoptotic Process Posttranscriptional Regulation Of Gene Expression Nuclear-transcribed MRNA Catabolic Process Programmed Cell Death Regulation Of Necrotic Cell Death MRNA Catabolic Process Cell Death Death Cellular Protein Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process RNA Catabolic Process Necroptotic Process Protein Ubiquitination RNA Metabolic Process Positive Regulation Of Protein Metabolic Process Protein Modification By Small Protein Conjugation Positive Regulation Of Signal Transduction Biosynthetic Process Regulation Of Protein Metabolic Process Regulation Of Immune System Process Negative Regulation Of Cell-matrix Adhesion Gene Expression Regulation Of Proteolysis Regulation Of Innate Immune Response Regulation Of Toll-like Receptor Signaling Pathway NIK/NF-kappaB Signaling Programmed Necrotic Cell Death Cellular Macromolecule Biosynthetic Process Necrotic Cell Death Negative Regulation Of Endopeptidase Activity Regulation Of Apoptotic Process
Tagcloud ?		acta2 amscs architectural cd105 cd73 cd90 chondrogenic confluence confluent cyto eng fibroblastic nes npat nt5e pou5f1 renewing rnaseq sfrp2 sfrp4 successively thy1 versatility wisp2 wnt2 wnt2b wnt5a wnt5b wnt7b	abnormally blasts bmmncs chest clustered customized ddit3 dimerization ets etv1 helicase mad max microarray pathogenetic raeb raebt refractory ribs rnahp rtc semiquantitative seventeen tensin thbs1 thrombocytopenia thrombospondin transcriptome try
Tagcloud (Difference) ?		acta2 amscs architectural cd105 cd73 cd90 chondrogenic confluence confluent cyto eng fibroblastic nes npat nt5e pou5f1 renewing rnaseq sfrp2 sfrp4 successively thy1 versatility wisp2 wnt2 wnt2b wnt5a wnt5b wnt7b	abnormally blasts bmmncs chest clustered customized ddit3 dimerization ets etv1 helicase mad max microarray pathogenetic raeb raebt refractory ribs rnahp rtc semiquantitative seventeen tensin thbs1 thrombocytopenia thrombospondin transcriptome try
Tagcloud (Intersection) ?