HINFP and ZNHIT1

Number of citations of the paper that reports this interaction (PubMedID 17577209)
0

Data Source:
BioGRID (two hybrid)

		HINFP	ZNHIT1
Description		histone H4 transcription factor	zinc finger HIT-type containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cajal Body	Nucleosome Swr1 Complex Nucleus Nucleoplasm
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Enzyme Binding Histone Binding Metal Ion Binding	Chromatin Binding Protein Binding Zinc Ion Binding Nucleosome Binding Histone Binding Histone Deacetylase Binding Metal Ion Binding
	Biological Process	DNA Damage Checkpoint Signaling G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription By RNA Polymerase II In Utero Embryonic Development DNA Repair DNA-templated Transcription Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Cell Cycle G1/S Phase Transition Establishment Of Protein Localization Myoblast Differentiation Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Heart Process Chromatin Organization Chromatin Remodeling Regulation Of DNA-templated Transcription Intestinal Stem Cell Homeostasis Regulation Of T Cell Proliferation Muscle Cell Differentiation Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Transcription Initiation-coupled Chromatin Remodeling Calcium Ion Homeostasis Positive Regulation Of Transcription Initiation By RNA Polymerase II Hematopoietic Stem Cell Homeostasis Negative Regulation Of G0 To G1 Transition Positive Regulation Of Lymphoid Progenitor Cell Differentiation
Pathways
Drugs
Diseases
GWAS
Interacting Genes		30 interacting genes: ATN1 CDYL2 EFTUD2 ELP4 GSPT1 IHO1 JUND MBD2 MDC1 MIF4GD MKI67 MORF4L1 NDUFAB1 NIPBL NPDC1 POM121C PRRC2C RBM17 RBM26 RPUSD4 TLE3 TP53 TRA2B TRAF2 TRIM39 TRIM44 TTF2 U2AF1 UFL1 ZNHIT1	23 interacting genes: APP BCL6 COL8A1 CSNK2B CYSRT1 DAPP1 FHL5 GOLGA6L9 GRB7 HINFP KANK2 KRTAP10-6 KRTAP10-7 KRTAP12-2 MAPK11 MAPK14 MAPK9 MDFI MYO5B OTX2 SH2D1A TNIP1 TP53
Entrez ID		25988	10467
HPRD ID		07387	15892
Ensembl ID		ENSG00000172273	ENSG00000106400
Uniprot IDs		Q9BQA5	O43257
PDB IDs			8X15 8X19 8X1C
Enriched GO Terms of Interacting Partners?		Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process Nucleoplasm MRNA Metabolic Process Nucleus Spliceosomal Complex DNA Damage Checkpoint Signaling RNA Splicing Regulation Of Cell Cycle Regulation Of Primary Metabolic Process RNA Metabolic Process MRNA Processing Negative Regulation Of Cell Cycle Process Signal Transduction In Response To DNA Damage Negative Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression RNA Binding Regulation Of Cell Cycle Process DNA Metabolic Process DNA Repair Mitotic DNA Damage Checkpoint Signaling Regulation Of Macromolecule Biosynthetic Process Macromolecule Metabolic Process Protein-containing Complex Mitotic DNA Integrity Checkpoint Signaling Positive Regulation Of Macromolecule Metabolic Process DNA Damage Response Negative Regulation Of Cell Cycle Negative Regulation Of Metabolic Process Regulation Of Macromolecule Metabolic Process MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Metabolic Process Transcription Corepressor Activity RNA Splicing, Via Transesterification Reactions Chromatin Organization Regulation Of Nucleobase-containing Compound Metabolic Process RNA Processing Programmed Necrotic Cell Death Double-strand Break Repair Hematopoietic Stem Cell Differentiation Transcription Elongation Factor Complex Hematopoietic Progenitor Cell Differentiation Site Of Double-strand Break Negative Regulation Of Cell Cycle Phase Transition Protein Binding Positive Regulation Of Macromolecule Biosynthetic Process Protein Stabilization DNA Recombination Regulation Of Protein Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process	Positive Regulation Of Reactive Oxygen Species Metabolic Process MAP Kinase Activity Cellular Senescence Negative Regulation Of Signal Transduction Negative Regulation Of Signaling Regulation Of Reactive Oxygen Species Metabolic Process Negative Regulation Of Cell Communication Negative Regulation Of Cell Cycle Process Stress-induced Premature Senescence NLRP1 Inflammasome Complex Assembly Positive Regulation Of Apoptotic Signaling Pathway Defense Response Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Programmed Necrotic Cell Death Positive Regulation Of Neuron Apoptotic Process Regulation Of Signal Transduction Regulation Of Cytokine Production Identical Protein Binding Inflammatory Response Negative Regulation Of Cell Cycle Cellular Response To UV-B Regulation Of MiRNA Processing Intracellular Signaling Cassette Necroptotic Process Regulation Of Regulatory NcRNA Processing Cellular Response To Oxygen-containing Compound Protein Serine/threonine Kinase Activity Cellular Response To UV Regulation Of Inflammatory Response Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Cell Cycle Phase Transition MAPK Cascade DNA Damage Checkpoint Signaling Programmed Necrotic Cell Death Positive Regulation Of Execution Phase Of Apoptosis Negative Regulation Of Cell Population Proliferation Regulation Of Transcription By RNA Polymerase II Molecular Function Activator Activity Regulation Of Cell Communication Regulation Of Signaling Negative Regulation Of DNA Replication Cellular Response To Light Stimulus P38MAPK Cascade Response To UV-B Stress-activated MAPK Cascade Positive Regulation Of Myeloid Cell Differentiation Stress-activated Protein Kinase Signaling Cascade Chromatin Binding Negative Regulation Of Macromolecule Metabolic Process Regulation Of MiRNA-mediated Gene Silencing
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