HINFP and EFTUD2

Number of citations of the paper that reports this interaction (PubMedID 17577209)
0

Data Source:
BioGRID (two hybrid)

		HINFP	EFTUD2
Description		histone H4 transcription factor	elongation factor Tu GTP binding domain containing 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cajal Body	Nucleus Nucleoplasm Spliceosomal Complex Cytosol Cajal Body Membrane Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Enzyme Binding Histone Binding Metal Ion Binding	Nucleotide Binding RNA Binding GTPase Activity Protein Binding GTP Binding U5 SnRNA Binding
	Biological Process	DNA Damage Checkpoint Signaling G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription By RNA Polymerase II In Utero Embryonic Development DNA Repair DNA-templated Transcription Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Cell Cycle G1/S Phase Transition Establishment Of Protein Localization Myoblast Differentiation Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Response To Cocaine Cellular Response To Xenobiotic Stimulus
Pathways			mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs
Diseases
GWAS			Asthma ( 31619474) Craniofacial microsomia ( 26853712)
Interacting Genes		30 interacting genes: ATN1 CDYL2 EFTUD2 ELP4 GSPT1 IHO1 JUND MBD2 MDC1 MIF4GD MKI67 MORF4L1 NDUFAB1 NIPBL NPDC1 POM121C PRRC2C RBM17 RBM26 RPUSD4 TLE3 TP53 TRA2B TRAF2 TRIM39 TRIM44 TTF2 U2AF1 UFL1 ZNHIT1	15 interacting genes: ARPC3 CYFIP1 DUX4 GOLM1 GSK3B HINFP LSM8 PIN1 PRPF6 SF3B3 SF3B4 SREK1 SUMO2 USP7 WBP4
Entrez ID		25988	9343
HPRD ID		07387	04869
Ensembl ID		ENSG00000172273	ENSG00000108883
Uniprot IDs		Q9BQA5	B3KX19 Q15029
PDB IDs			3JCR 5MQF 5O9Z 5XJC 5YZG 5Z56 5Z57 5Z58 6AH0 6AHD 6FF4 6FF7 6ICZ 6ID0 6ID1 6QDV 6QW6 6QX9 6ZYM 7AAV 7ABF 7ABG 7ABI 7DVQ 7QTT 7W59 7W5A 7W5B 8C6J 8CH6 8H6E 8H6J 8H6K 8H6L 8I0P 8I0R 8I0S 8I0T 8I0U 8I0V 8I0W 8Q7N 8Q7Q 8Q7V 8Q7W 8Q7X 8Q91 8QO9 8QOZ 8QP8 8QP9 8QPA 8QPB 8QPE 8QPK 8QXD 8QZS 8R08 8R09 8R0A 8R0B 8RC0 8RM5 8RO2 8Y6O 9FMD
Enriched GO Terms of Interacting Partners?		Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process Nucleoplasm MRNA Metabolic Process Nucleus Spliceosomal Complex DNA Damage Checkpoint Signaling RNA Splicing Regulation Of Cell Cycle Regulation Of Primary Metabolic Process RNA Metabolic Process MRNA Processing Negative Regulation Of Cell Cycle Process Signal Transduction In Response To DNA Damage Negative Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression RNA Binding Regulation Of Cell Cycle Process DNA Metabolic Process DNA Repair Mitotic DNA Damage Checkpoint Signaling Regulation Of Macromolecule Biosynthetic Process Macromolecule Metabolic Process Protein-containing Complex Mitotic DNA Integrity Checkpoint Signaling Positive Regulation Of Macromolecule Metabolic Process DNA Damage Response Negative Regulation Of Cell Cycle Negative Regulation Of Metabolic Process Regulation Of Macromolecule Metabolic Process MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Metabolic Process Transcription Corepressor Activity RNA Splicing, Via Transesterification Reactions Chromatin Organization Regulation Of Nucleobase-containing Compound Metabolic Process RNA Processing Programmed Necrotic Cell Death Double-strand Break Repair Hematopoietic Stem Cell Differentiation Transcription Elongation Factor Complex Hematopoietic Progenitor Cell Differentiation Site Of Double-strand Break Negative Regulation Of Cell Cycle Phase Transition Protein Binding Positive Regulation Of Macromolecule Biosynthetic Process Protein Stabilization DNA Recombination Regulation Of Protein Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process	U2-type Precatalytic Spliceosome Spliceosomal Complex MRNA Splicing, Via Spliceosome Precatalytic Spliceosome RNA Splicing RNA Splicing, Via Transesterification Reactions MRNA Processing Negative Regulation Of Protein Catabolic Process Spliceosomal Complex Assembly MRNA Metabolic Process Nucleoplasm Regulation Of Protein Catabolic Process RNA Processing RNA Metabolic Process Negative Regulation Of Protein Metabolic Process Nucleic Acid Metabolic Process U2-type Prespliceosome Assembly U12-type Spliceosomal Complex Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process U2 SnRNP Postsynaptic Cytosol U2-type Spliceosomal Complex Negative Regulation Of Catabolic Process Positive Regulation Of RNA Biosynthetic Process Nucleus Positive Regulation Of DNA-templated Transcription Regulation Of Ubiquitin-dependent Protein Catabolic Process Nuclear Speck Cellular Component Assembly Positive Regulation Of Transcription By RNA Polymerase II U4/U6 X U5 Tri-snRNP Complex Positive Regulation Of RNA Metabolic Process Regulation Of Proteasomal Protein Catabolic Process Tau Protein Binding Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Macromolecule Metabolic Process Regulation Of Microtubule Anchoring At Centrosome Cis-trans Isomerase Activity Growth Cone Leading Edge Protein-RNA Complex Assembly Nucleobase-containing Compound Metabolic Process Postsynapse Positive Regulation Of Nucleobase-containing Compound Metabolic Process Cell Leading Edge Glutamatergic Synapse Negative Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Nucleic Acid Binding Superior Temporal Gyrus Development Negative Regulation Of Type B Pancreatic Cell Development
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