HINFP and CDYL2

Number of citations of the paper that reports this interaction (PubMedID 17577209)
0

Data Source:
BioGRID (two hybrid)

		HINFP	CDYL2
Description		histone H4 transcription factor	chromodomain Y like 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cajal Body	Nucleus
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Enzyme Binding Histone Binding Metal Ion Binding	Transcription Corepressor Activity Protein Binding Histone H3K27me3 Reader Activity Histone H3K9me2/3 Reader Activity
	Biological Process	DNA Damage Checkpoint Signaling G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription By RNA Polymerase II In Utero Embryonic Development DNA Repair DNA-templated Transcription Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Cell Cycle G1/S Phase Transition Establishment Of Protein Localization Myoblast Differentiation Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II	Chromatin Organization Negative Regulation Of DNA-templated Transcription
Pathways
Drugs
Diseases
GWAS			Breast cancer ( 23535729 29059683) Inflammatory bowel disease ( 27569725) Interleukin-10 levels ( 22205395) Liver enzyme levels (alkaline phosphatase) ( 33972514) Metabolite levels ( 23823483) Prostate cancer ( 31748686) Pulse pressure ( 30224653) Serum alkaline phosphatase levels ( 33547301)
Interacting Genes		30 interacting genes: ATN1 CDYL2 EFTUD2 ELP4 GSPT1 IHO1 JUND MBD2 MDC1 MIF4GD MKI67 MORF4L1 NDUFAB1 NIPBL NPDC1 POM121C PRRC2C RBM17 RBM26 RPUSD4 TLE3 TP53 TRA2B TRAF2 TRIM39 TRIM44 TTF2 U2AF1 UFL1 ZNHIT1	11 interacting genes: DVL3 H3-4 H3C1 HINFP HSF2BP LIG1 LMO3 NXF1 PRMT5 SPANXN2 ZBTB9
Entrez ID		25988	124359
HPRD ID		07387	10819
Ensembl ID		ENSG00000172273	ENSG00000166446
Uniprot IDs		Q9BQA5	Q8N8U2
PDB IDs			2MJ8 4HAE 5JJZ 6V2D 6V2H 6V3N 6V8W 8SP6
Enriched GO Terms of Interacting Partners?		Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process Nucleoplasm MRNA Metabolic Process Nucleus Spliceosomal Complex DNA Damage Checkpoint Signaling RNA Splicing Regulation Of Cell Cycle Regulation Of Primary Metabolic Process RNA Metabolic Process MRNA Processing Negative Regulation Of Cell Cycle Process Signal Transduction In Response To DNA Damage Negative Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression RNA Binding Regulation Of Cell Cycle Process DNA Metabolic Process DNA Repair Mitotic DNA Damage Checkpoint Signaling Regulation Of Macromolecule Biosynthetic Process Macromolecule Metabolic Process Protein-containing Complex Mitotic DNA Integrity Checkpoint Signaling Positive Regulation Of Macromolecule Metabolic Process DNA Damage Response Negative Regulation Of Cell Cycle Negative Regulation Of Metabolic Process Regulation Of Macromolecule Metabolic Process MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Metabolic Process Transcription Corepressor Activity RNA Splicing, Via Transesterification Reactions Chromatin Organization Regulation Of Nucleobase-containing Compound Metabolic Process RNA Processing Programmed Necrotic Cell Death Double-strand Break Repair Hematopoietic Stem Cell Differentiation Transcription Elongation Factor Complex Hematopoietic Progenitor Cell Differentiation Site Of Double-strand Break Negative Regulation Of Cell Cycle Phase Transition Protein Binding Positive Regulation Of Macromolecule Biosynthetic Process Protein Stabilization DNA Recombination Regulation Of Protein Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process	Okazaki Fragment Processing Involved In Mitotic DNA Replication Nucleobase-containing Compound Biosynthetic Process DNA Ligase (ATP) Activity Lagging Strand Elongation DNA Replication, Okazaki Fragment Processing Macromolecule Biosynthetic Process DNA Ligase Activity Chromosome Protein Heterodimerization Activity Structural Constituent Of Chromatin Positive Regulation Of Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Peptidyl-arginine N-methylation Histone Arginine N-methyltransferase Activity Protein-arginine Omega-N Symmetric Methyltransferase Activity Positive Regulation Of Nuclear Receptor-mediated Glucocorticoid Signaling Pathway Nucleosome Assembly Nucleosome Nucleosome Organization Spermatogonial Cell Division Histone H4R3 Methyltransferase Activity Positive Regulation Of Dopamine Receptor Signaling Pathway Peptidyl-arginine Methylation
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