HINFP and PRRC2C

Number of citations of the paper that reports this interaction (PubMedID 17577209)
0

Data Source:
BioGRID (pull down)

		HINFP	PRRC2C
Description		histone H4 transcription factor	proline rich coiled-coil 2C
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cajal Body	Cytoplasm Cytosol Cytoplasmic Stress Granule Membrane
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Enzyme Binding Histone Binding Metal Ion Binding	RNA Binding Protein Binding
	Biological Process	DNA Damage Checkpoint Signaling G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription By RNA Polymerase II In Utero Embryonic Development DNA Repair DNA-templated Transcription Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Cell Cycle G1/S Phase Transition Establishment Of Protein Localization Myoblast Differentiation Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II	Hematopoietic Progenitor Cell Differentiation Stress Granule Assembly
Pathways
Drugs
Diseases
GWAS			Adult body size ( 32376654) Alzheimer's disease (cognitive decline) ( 23535033) Cognitive decline rate in late mild cognitive impairment ( 26252872) Creatinine levels ( 29403010) Daytime nap ( 33568662) Estimated glomerular filtration rate ( 31015462 31152163) Glomerular filtration rate ( 29403010) HDL cholesterol levels ( 32203549) Microalbuminuria ( 31511532) Platelet distribution width ( 32888494) Urinary albumin excretion ( 30220432) Urinary albumin-to-creatinine ratio ( 31511532 31630189)
Interacting Genes		30 interacting genes: ATN1 CDYL2 EFTUD2 ELP4 GSPT1 IHO1 JUND MBD2 MDC1 MIF4GD MKI67 MORF4L1 NDUFAB1 NIPBL NPDC1 POM121C PRRC2C RBM17 RBM26 RPUSD4 TLE3 TP53 TRA2B TRAF2 TRIM39 TRIM44 TTF2 U2AF1 UFL1 ZNHIT1	4 interacting genes: CEBPA HINFP RNF10 SRPK2
Entrez ID		25988	23215
HPRD ID		07387	16539
Ensembl ID		ENSG00000172273	ENSG00000117523
Uniprot IDs		Q9BQA5	E7EPN9 Q9Y520
PDB IDs
Enriched GO Terms of Interacting Partners?		Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process Nucleoplasm MRNA Metabolic Process Nucleus Spliceosomal Complex DNA Damage Checkpoint Signaling RNA Splicing Regulation Of Cell Cycle Regulation Of Primary Metabolic Process RNA Metabolic Process MRNA Processing Negative Regulation Of Cell Cycle Process Signal Transduction In Response To DNA Damage Negative Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression RNA Binding Regulation Of Cell Cycle Process DNA Metabolic Process DNA Repair Mitotic DNA Damage Checkpoint Signaling Regulation Of Macromolecule Biosynthetic Process Macromolecule Metabolic Process Protein-containing Complex Mitotic DNA Integrity Checkpoint Signaling Positive Regulation Of Macromolecule Metabolic Process DNA Damage Response Negative Regulation Of Cell Cycle Negative Regulation Of Metabolic Process Regulation Of Macromolecule Metabolic Process MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Metabolic Process Transcription Corepressor Activity RNA Splicing, Via Transesterification Reactions Chromatin Organization Regulation Of Nucleobase-containing Compound Metabolic Process RNA Processing Programmed Necrotic Cell Death Double-strand Break Repair Hematopoietic Stem Cell Differentiation Transcription Elongation Factor Complex Hematopoietic Progenitor Cell Differentiation Site Of Double-strand Break Negative Regulation Of Cell Cycle Phase Transition Protein Binding Positive Regulation Of Macromolecule Biosynthetic Process Protein Stabilization DNA Recombination Regulation Of Protein Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process	Nucleolus Transcription Cis-regulatory Region Binding Regulation Of RNA Metabolic Process RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process Response To Vitamin B2 C/EBP Complex Positive Regulation Of Biosynthetic Process Response To Lithium Ion Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Negative Regulation Of RNA Metabolic Process Transcription By RNA Polymerase I Urea Metabolic Process Negative Regulation Of DNA-templated Transcription Regulation Of Hematopoietic Stem Cell Proliferation Regulation Of Macromolecule Biosynthetic Process Signal Transduction Cellular Response To Lithium Ion CHOP-C/EBP Complex HMG Box Domain Binding Response To Phenylpropanoid Regulation Of Primary Metabolic Process Positive Regulation Of Gene Expression RNA Metabolic Process Regulation Of Protein Catabolic Process Negative Regulation Of Cell Cycle Nitrogen Cycle Metabolic Process White Fat Cell Differentiation Regulation Of Macromolecule Metabolic Process Urea Cycle Interleukin-6-mediated Signaling Pathway Regulation Of RNA Biosynthetic Process DNA Binding Regulation Of Gene Expression Negative Regulation Of Cell Development White Fat Cell Proliferation Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Cell Cycle Negative Regulation Of RNA Biosynthetic Process STAT Family Protein Binding Positive Regulation Of Transcription By RNA Polymerase II Osteoblast Development Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex Fat Cell Proliferation R-loop Processing Nuclear Speck Organization Negative Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I
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