HINFP and RPUSD4

Number of citations of the paper that reports this interaction (PubMedID 17577209)
0

Data Source:
BioGRID (two hybrid)

		HINFP	RPUSD4
Description		histone H4 transcription factor	RNA pseudouridine synthase D4
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cajal Body	Nucleus Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Matrix Ribonucleoprotein Granule
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Enzyme Binding Histone Binding Metal Ion Binding	TRNA Binding RNA Binding Protein Binding Pseudouridine Synthase Activity Isomerase Activity TRNA Pseudouridine Synthase Activity Mitochondrial Ribosomal Large Subunit RRNA Binding
	Biological Process	DNA Damage Checkpoint Signaling G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription By RNA Polymerase II In Utero Embryonic Development DNA Repair DNA-templated Transcription Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Cell Cycle G1/S Phase Transition Establishment Of Protein Localization Myoblast Differentiation Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II	Pseudouridine Synthesis RRNA Processing MRNA Processing TRNA Processing RNA Splicing RNA Modification RRNA Pseudouridine Synthesis Positive Regulation Of Mitochondrial Translation Mitochondrial TRNA Pseudouridine Synthesis MRNA Pseudouridine Synthesis
Pathways			rRNA modification in the mitochondrion Mitochondrial mRNA modification
Drugs
Diseases
GWAS			Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer ( 28429243) FEV1 ( 30804560) Heart failure ( 20445134) Lung function (FEV1) ( 28166213) Lung function (FEV1/FVC) ( 30804560) Metabolite levels ( 23823483) Peak expiratory flow ( 30804560)
Interacting Genes		30 interacting genes: ATN1 CDYL2 EFTUD2 ELP4 GSPT1 IHO1 JUND MBD2 MDC1 MIF4GD MKI67 MORF4L1 NDUFAB1 NIPBL NPDC1 POM121C PRRC2C RBM17 RBM26 RPUSD4 TLE3 TP53 TRA2B TRAF2 TRIM39 TRIM44 TTF2 U2AF1 UFL1 ZNHIT1	1 interacting genes: HINFP
Entrez ID		25988	84881
HPRD ID		07387	07862
Ensembl ID		ENSG00000172273	ENSG00000165526
Uniprot IDs		Q9BQA5	B4DUN4 Q96CM3
PDB IDs			5UBA
Enriched GO Terms of Interacting Partners?		Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process Nucleoplasm MRNA Metabolic Process Nucleus Spliceosomal Complex DNA Damage Checkpoint Signaling RNA Splicing Regulation Of Cell Cycle Regulation Of Primary Metabolic Process RNA Metabolic Process MRNA Processing Negative Regulation Of Cell Cycle Process Signal Transduction In Response To DNA Damage Negative Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression RNA Binding Regulation Of Cell Cycle Process DNA Metabolic Process DNA Repair Mitotic DNA Damage Checkpoint Signaling Regulation Of Macromolecule Biosynthetic Process Macromolecule Metabolic Process Protein-containing Complex Mitotic DNA Integrity Checkpoint Signaling Positive Regulation Of Macromolecule Metabolic Process DNA Damage Response Negative Regulation Of Cell Cycle Negative Regulation Of Metabolic Process Regulation Of Macromolecule Metabolic Process MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Metabolic Process Transcription Corepressor Activity RNA Splicing, Via Transesterification Reactions Chromatin Organization Regulation Of Nucleobase-containing Compound Metabolic Process RNA Processing Programmed Necrotic Cell Death Double-strand Break Repair Hematopoietic Stem Cell Differentiation Transcription Elongation Factor Complex Hematopoietic Progenitor Cell Differentiation Site Of Double-strand Break Negative Regulation Of Cell Cycle Phase Transition Protein Binding Positive Regulation Of Macromolecule Biosynthetic Process Protein Stabilization DNA Recombination Regulation Of Protein Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process
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