HINFP and NDUFAB1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		HINFP	NDUFAB1
Description		histone H4 transcription factor	NADH:ubiquinone oxidoreductase subunit AB1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cajal Body	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Mitochondrial Membrane Respiratory Chain Complex I Mitochondrial [2Fe-2S] Assembly Complex Iron-sulfur Cluster Assembly Complex
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Enzyme Binding Histone Binding Metal Ion Binding	Acyl Binding Acyl Carrier Activity Structural Molecule Activity Fatty Acid Binding Calcium Ion Binding Protein Binding Mitochondrial Large Ribosomal Subunit Binding
	Biological Process	DNA Damage Checkpoint Signaling G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription By RNA Polymerase II In Utero Embryonic Development DNA Repair DNA-templated Transcription Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Cell Cycle G1/S Phase Transition Establishment Of Protein Localization Myoblast Differentiation Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II	Mitochondrial Electron Transport, NADH To Ubiquinone Lipid Metabolic Process Fatty Acid Metabolic Process Fatty Acid Biosynthetic Process Aerobic Respiration Protein Lipoylation Iron-sulfur Cluster Assembly Proton Motive Force-driven Mitochondrial ATP Synthesis [2Fe-2S] Cluster Assembly
Pathways			Respiratory electron transport Complex I biogenesis Mitochondrial Fatty Acid Beta-Oxidation Protein lipoylation Mitochondrial ribosome-associated quality control
Drugs			NADH
Diseases
GWAS			Bipolar disorder ( 17554300)
Interacting Genes		30 interacting genes: ATN1 CDYL2 EFTUD2 ELP4 GSPT1 IHO1 JUND MBD2 MDC1 MIF4GD MKI67 MORF4L1 NDUFAB1 NIPBL NPDC1 POM121C PRRC2C RBM17 RBM26 RPUSD4 TLE3 TP53 TRA2B TRAF2 TRIM39 TRIM44 TTF2 U2AF1 UFL1 ZNHIT1	35 interacting genes: ACTN3 BBC3 BEX5 CCDC24 CNTF EIF3B ERBB3 FEM1A FHL3 FNDC3B HINFP KCTD9 LMO2 LNX1 MBLAC1 MORN3 MRPL23 NOXA1 NRF1 NT5C3A NTAQ1 OIP5 POP5 PPP1R16A PSMC3 RBM18 SLIRP SMYD3 THAP1 TLX3 TOX2 VAC14 ZNF19 ZNF410 ZNF829
Entrez ID		25988	4706
HPRD ID		07387	11951
Ensembl ID		ENSG00000172273	ENSG00000004779
Uniprot IDs		Q9BQA5	O14561
PDB IDs			2DNW 5OOL 5OOM 5XTB 5XTC 5XTD 5XTH 5XTI 6ODD 7A5H 7A5J 7O9K 7O9M 7ODR 7ODS 7ODT 7OF0 7OF2 7OF3 7OF5 7OF7 7OI6 7OI7 7OI8 7OI9 7OIC 7OID 7OIE 7PD3 7PO4 7QH6 7QH7 8K2B 8PK0 8QSJ 8QU5
Enriched GO Terms of Interacting Partners?		Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process Nucleoplasm MRNA Metabolic Process Nucleus Spliceosomal Complex DNA Damage Checkpoint Signaling RNA Splicing Regulation Of Cell Cycle Regulation Of Primary Metabolic Process RNA Metabolic Process MRNA Processing Negative Regulation Of Cell Cycle Process Signal Transduction In Response To DNA Damage Negative Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression RNA Binding Regulation Of Cell Cycle Process DNA Metabolic Process DNA Repair Mitotic DNA Damage Checkpoint Signaling Regulation Of Macromolecule Biosynthetic Process Macromolecule Metabolic Process Protein-containing Complex Mitotic DNA Integrity Checkpoint Signaling Positive Regulation Of Macromolecule Metabolic Process DNA Damage Response Negative Regulation Of Cell Cycle Negative Regulation Of Metabolic Process Regulation Of Macromolecule Metabolic Process MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Metabolic Process Transcription Corepressor Activity RNA Splicing, Via Transesterification Reactions Chromatin Organization Regulation Of Nucleobase-containing Compound Metabolic Process RNA Processing Programmed Necrotic Cell Death Double-strand Break Repair Hematopoietic Stem Cell Differentiation Transcription Elongation Factor Complex Hematopoietic Progenitor Cell Differentiation Site Of Double-strand Break Negative Regulation Of Cell Cycle Phase Transition Protein Binding Positive Regulation Of Macromolecule Biosynthetic Process Protein Stabilization DNA Recombination Regulation Of Protein Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process
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