MYPN and NEBL

Number of citations of the paper that reports this interaction (PMID 11309420)
43

Data Source:
HPRD (two hybrid)

		MYPN	NEBL
Gene Name		myopalladin	nebulette
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Z Disc I Band	Stress Fiber Z Disc I Band Extracellular Vesicular Exosome
	Molecular Function	Actin Binding Protein Binding Cytoskeletal Protein Binding SH3 Domain Binding Muscle Alpha-actinin Binding	Protein Binding Tropomyosin Binding Cytoskeletal Protein Binding Structural Constituent Of Muscle Filamin Binding Actin Filament Binding
	Biological Process	Sarcomere Organization	Cardiac Muscle Thin Filament Assembly
Pathways
Drugs
Diseases
GWAS		Optic disc size (disc) ( 20395239)	Ovarian cancer ( 23535730)
Protein-Protein Interactions		7 interactors: ACTN2 ACTN3 ANKRD1 ANKRD23 NEB NEBL TTN	23 interactors: ACTB ACTN1 ACTN3 CCDC136 FAM9B GMCL1 GOLGA2 HOMER3 LZTS2 MAD1L1 MIPOL1 MYPN NUTM1 PRKAB2 TRAF1 TRAF2 TRIM27 TRIM55 TRIM63 XIRP1 XIRP2 ZDHHC17 ZYX
Entrez ID		84665	10529
HPRD ID		10536	10403
Ensembl ID		ENSG00000138347	ENSG00000078114
Uniprot IDs		Q86TC9	O76041 Q59FZ8
PDB IDs			4F14
Enriched GO Terms of Interacting Partners?		Actin-myosin Filament Sliding Muscle Filament Sliding Actin-mediated Cell Contraction Actin Filament-based Movement Actin Filament-based Process Muscle Contraction Muscle System Process Myofibril Assembly Response To Muscle Stretch Actomyosin Structure Organization Muscle Structure Development Striated Muscle Cell Development Muscle Cell Development Cardiac Muscle Tissue Development Cardiac Myofibril Assembly Response To Mechanical Stimulus Striated Muscle Cell Differentiation Focal Adhesion Assembly Muscle Organ Development Cellular Component Assembly Striated Muscle Tissue Development Adherens Junction Assembly Muscle Cell Differentiation Muscle Tissue Development Cell-substrate Junction Assembly Sarcomere Organization Cardiac Muscle Tissue Morphogenesis Muscle Tissue Morphogenesis Cardiac Muscle Cell Development Muscle Organ Morphogenesis Platelet Degranulation Organelle Assembly Adherens Junction Organization Cardiac Muscle Thin Filament Assembly Heart Development Cardiac Muscle Cell Differentiation Movement Of Cell Or Subcellular Component Actin Cytoskeleton Organization Cardiocyte Differentiation Sarcomerogenesis Detection Of Muscle Stretch Skeletal Muscle Myosin Thick Filament Assembly Cell-matrix Adhesion Directional Locomotion Platelet Activation Myosin Filament Assembly Cell Junction Assembly Cardiovascular System Development Cell-cell Junction Organization Cell-substrate Adhesion	Actin Filament-based Process Cellular Component Assembly Actin Cytoskeleton Organization Cytoskeleton Organization Cell-cell Junction Organization Organelle Organization Adherens Junction Organization Actomyosin Structure Organization Focal Adhesion Assembly Cell-matrix Adhesion Protein K63-linked Ubiquitination Protein Trimerization Cell Junction Assembly Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cell-substrate Adhesion Adherens Junction Assembly Signal Transduction Cell-substrate Junction Assembly Sarcomere Organization Regulation Of Metaphase Plate Congression Actin Filament Bundle Assembly Signaling Cell Communication Actin Filament Organization Negative Regulation Of Interleukin-2 Secretion Myofibril Assembly Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Cellular Process Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Protein Localization To Tight Junction Cellular Process Positive Regulation Of NF-kappaB Transcription Factor Activity
Tagcloud ?			anatomical assumes bcc bccs binomial correction crnkl1 drivers exome genesis hot intermittent invex landscape lend melanomas mutational passengers patched permutation pick ptch1 sccs sequenced spots stat5b stringent uniform uniquely
Tagcloud (Difference) ?			anatomical assumes bcc bccs binomial correction crnkl1 drivers exome genesis hot intermittent invex landscape lend melanomas mutational passengers patched permutation pick ptch1 sccs sequenced spots stat5b stringent uniform uniquely
Tagcloud (Intersection) ?