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MYPN and ACTN3
Number of citations of the paper that reports this interaction (PMID
11309420
)
43
Data Source:
HPRD
(two hybrid)
MYPN
ACTN3
Gene Name
myopalladin
actinin, alpha 3 (gene/pseudogene)
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Z Disc
I Band
Cytosol
Actin Filament
Focal Adhesion
Pseudopodium
Extracellular Vesicular Exosome
Molecular Function
Actin Binding
Protein Binding
Cytoskeletal Protein Binding
SH3 Domain Binding
Muscle Alpha-actinin Binding
Actin Binding
Integrin Binding
Calcium Ion Binding
Protein Binding
Structural Constituent Of Muscle
Protein Homodimerization Activity
Biological Process
Sarcomere Organization
Muscle Filament Sliding
Regulation Of Apoptotic Process
Focal Adhesion Assembly
Pathways
Striated Muscle Contraction
Nephrin interactions
Drugs
Diseases
GWAS
Optic disc size (disc) (
20395239
)
Bipolar disorder (
21926972
)
Protein-Protein Interactions
7 interactors:
ACTN2
ACTN3
ANKRD1
ANKRD23
NEB
NEBL
TTN
17 interactors:
ABI3
ACTN1
ACTN2
ACTN4
ADORA2A
BRCA1
C1orf94
KCTD6
MYPN
NEBL
NRAP
PLEKHG2
REL
RNF111
SUMO1P1
TRAF1
TRAF2
Entrez ID
84665
89
HPRD ID
10536
02148
Ensembl ID
ENSG00000138347
ENSG00000248746
Uniprot IDs
Q86TC9
B4DZQ2
Q08043
Q4VAM3
PDB IDs
1TJT
1WKU
3LUE
Enriched GO Terms of Interacting Partners
?
Actin-myosin Filament Sliding
Muscle Filament Sliding
Actin-mediated Cell Contraction
Actin Filament-based Movement
Actin Filament-based Process
Muscle Contraction
Muscle System Process
Myofibril Assembly
Response To Muscle Stretch
Actomyosin Structure Organization
Muscle Structure Development
Striated Muscle Cell Development
Muscle Cell Development
Cardiac Muscle Tissue Development
Cardiac Myofibril Assembly
Response To Mechanical Stimulus
Striated Muscle Cell Differentiation
Focal Adhesion Assembly
Muscle Organ Development
Cellular Component Assembly
Striated Muscle Tissue Development
Adherens Junction Assembly
Muscle Cell Differentiation
Muscle Tissue Development
Cell-substrate Junction Assembly
Sarcomere Organization
Cardiac Muscle Tissue Morphogenesis
Muscle Tissue Morphogenesis
Cardiac Muscle Cell Development
Muscle Organ Morphogenesis
Platelet Degranulation
Organelle Assembly
Adherens Junction Organization
Cardiac Muscle Thin Filament Assembly
Heart Development
Cardiac Muscle Cell Differentiation
Movement Of Cell Or Subcellular Component
Actin Cytoskeleton Organization
Cardiocyte Differentiation
Sarcomerogenesis
Detection Of Muscle Stretch
Skeletal Muscle Myosin Thick Filament Assembly
Cell-matrix Adhesion
Directional Locomotion
Platelet Activation
Myosin Filament Assembly
Cell Junction Assembly
Cardiovascular System Development
Cell-cell Junction Organization
Cell-substrate Adhesion
Protein Localization To Tight Junction
Regulation Of Cell Death
Cellular Component Assembly
Protein Localization To Cell Junction
Platelet Degranulation
Regulation Of Apoptotic Process
Actin Filament-based Process
Actin Crosslink Formation
Blood Coagulation
Hemostasis
Protein Polyubiquitination
Focal Adhesion Assembly
Platelet Activation
Apoptotic Process
Cell Junction Assembly
Regulation Of Extrinsic Apoptotic Signaling Pathway
NIK/NF-kappaB Signaling
Cell-cell Junction Organization
Programmed Cell Death
Protein Autoubiquitination
Cell Death
Death
Regulation Of Body Fluid Levels
Tight Junction Assembly
Adherens Junction Assembly
Actin Cytoskeleton Organization
Wound Healing
Cytoskeleton Organization
Positive Regulation Of Ion Transmembrane Transporter Activity
Cell-substrate Junction Assembly
Protein Homooligomerization
Positive Regulation Of Transporter Activity
I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Histone H4-K20 Methylation
Positive Regulation Of Histone H4-K16 Acetylation
Cardiac Muscle Thin Filament Assembly
Actin Filament Bundle Assembly
Response To Wounding
Regulation Of Signal Transduction
Actin Filament Organization
Apical Junction Assembly
Regulation Of Nitrogen Compound Metabolic Process
Positive Regulation Of Ion Transmembrane Transport
Myofibril Assembly
Exocytosis
Positive Regulation Of Histone H3-K9 Acetylation
Positive Regulation Of Cytokine Production
Adherens Junction Organization
Regulation Of Signaling
Cellular Response To Tumor Necrosis Factor
Tagcloud
?
ace
bdkrb2
chi2
cl
cmj
competition
counter
discriminate
distributions
elite
explosive
forward
genotypic
italian
italians
jump
leg
look
players
sedentary
sj
soccer
squat
stepwise
strength
top
traits
variance
Tagcloud (Difference)
?
ace
bdkrb2
chi2
cl
cmj
competition
counter
discriminate
distributions
elite
explosive
forward
genotypic
italian
italians
jump
leg
look
players
sedentary
sj
soccer
squat
stepwise
strength
top
traits
variance
Tagcloud (Intersection)
?