SAP30 and BRMS1

Number of citations of the paper that reports this interaction (PMID 15451426)
21

Data Source:
HPRD (in vivo)

		SAP30	BRMS1
Gene Name		Sin3A-associated protein, 30kDa	breast cancer metastasis suppressor 1
Image
Gene Ontology Annotations	Cellular Component	Histone Deacetylase Complex Nucleoplasm	Nucleus Nucleoplasm Cytoplasm Sin3-type Complex
	Molecular Function	DNA Binding Transcription Corepressor Activity Protein Binding Metal Ion Binding	Histone Deacetylase Activity Protein Binding Histone Deacetylase Binding NF-kappaB Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Organization Transcription, DNA-templated Regulation Of Transcription, DNA-templated Gene Expression Skeletal Muscle Cell Differentiation Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression, Epigenetic	Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Organization Transcription, DNA-templated Apoptotic Process Histone Deacetylation Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Protein Deacetylation Positive Regulation Of Anoikis
Pathways		NoRC negatively regulates rRNA expression Chromatin modifying enzymes Chromatin organization HDACs deacetylate histones Epigenetic regulation of gene expression Negative epigenetic regulation of rRNA expression	Chromatin modifying enzymes Chromatin organization HDACs deacetylate histones
Drugs
Diseases
GWAS			Bipolar disorder ( 21926972)
Protein-Protein Interactions		27 interactors: ARID4A BRMS1 BRMS1L CIR1 HBP1 HDAC1 HDAC2 HIST1H2AL HIST2H2BE HIST3H3 HIST4H4 HTT ID3 ING1 LINC00152 MXD1 NCOR1 NCOR2 PCBD1 RBBP4 RBBP7 RBP1 SAMSN1 SAP30BP SIN3A YY1 ZNF395	36 interactors: APP ARID4A BRMS1L CEP70 DNAJB1 DNAJB6 EEF1A1 EP300 GOLGB1 HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HSP90AA1 HSPA4 ING1 KPNA5 LINC00152 LRIF1 NMI PFDN5 RBBP4 RBBP7 RBP1 RELA SAP30 SIN3A SMARCE1 SMTN SNX6 SPOP SUDS3 TAF1 UBE2D1
Entrez ID		8819	25855
HPRD ID		04540	05879
Ensembl ID		ENSG00000164105	ENSG00000174744
Uniprot IDs		O75446	G5E9I4 Q9HCU9
PDB IDs		2KDP	2XUS 4AUV
Enriched GO Terms of Interacting Partners?		Chromosome Organization Negative Regulation Of Gene Expression Chromatin Organization Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Chromatin Modification Negative Regulation Of Biosynthetic Process Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression, Epigenetic Gene Expression Heterocycle Metabolic Process Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process RNA Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Organelle Organization Regulation Of Metabolic Process Histone Deacetylation Histone Modification Protein Deacetylation ATP-dependent Chromatin Remodeling Rhythmic Process Histone H3-K9 Modification Transcription From RNA Polymerase II Promoter Circadian Rhythm Chromatin Remodeling CENP-A Containing Nucleosome Assembly Histone Exchange DNA Replication-independent Nucleosome Assembly Homeostatic Process Nucleosome Assembly Cellular Metabolic Process Chromatin Assembly Establishment Of Sertoli Cell Barrier	Chromatin Organization Chromatin Modification Histone Deacetylation Negative Regulation Of Transcription, DNA-templated Protein Deacetylation Negative Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression, Epigenetic Histone H3-K9 Modification Chromosome Organization Negative Regulation Of Biosynthetic Process Histone Modification Negative Regulation Of Cellular Metabolic Process Organelle Organization Negative Regulation Of Gene Expression, Epigenetic Histone H4 Deacetylation Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Histone H3 Deacetylation Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter RNA Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Regulation Of Gene Expression Cellular Response To Heat Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Chromatin Remodeling Positive Regulation Of Macromolecule Biosynthetic Process Response To Heat Positive Regulation Of Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process ATP-dependent Chromatin Remodeling Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Protein Metabolic Process Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process
Tagcloud ?		affects chip deacetylation detecting differential dual encoded enzyme hdac herpes hsv htrp inhibit interact kmb luciferase lysine msin3a promote real regulator repressor reveal significance simplex synergistically transfer viral whose	adh6 aflatoxin areca arecoline bard1 betel ccnd2 cdk2ap1 cdkn1a cdkn2b chewing exonic fermented fgfr4 flnc gas1 hras il12b il8 indels msh6 nbl1 nitrosamines northeast nut quid rassf1 tobacco toxogenomic
Tagcloud (Difference) ?		affects chip deacetylation detecting differential dual encoded enzyme hdac herpes hsv htrp inhibit interact kmb luciferase lysine msin3a promote real regulator repressor reveal significance simplex synergistically transfer viral whose	adh6 aflatoxin areca arecoline bard1 betel ccnd2 cdk2ap1 cdkn1a cdkn2b chewing exonic fermented fgfr4 flnc gas1 hras il12b il8 indels msh6 nbl1 nitrosamines northeast nut quid rassf1 tobacco toxogenomic
Tagcloud (Intersection) ?