SAP30 and H2AC16

Number of citations of the paper that reports this interaction (PubMedID 9651585)
0

Data Source:
HPRD (in vivo)

		SAP30	H2AC16
Description		Sin3A associated protein 30	H2A clustered histone 16
Image
GO Annotations	Cellular Component	Histone Deacetylase Complex Nucleus Nucleoplasm Sin3-type Complex	Nucleosome Nucleus Chromosome Extracellular Exosome
	Molecular Function	DNA Binding Transcription Coregulator Activity Transcription Corepressor Activity Protein Binding Zinc Ion Binding Metal Ion Binding	DNA Binding Protein Binding Enzyme Binding Structural Constituent Of Chromatin Protein Heterodimerization Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Negative Regulation Of Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Skeletal Muscle Cell Differentiation Negative Regulation Of Stem Cell Population Maintenance Positive Regulation Of Stem Cell Population Maintenance	Heterochromatin Formation
Pathways		HDACs deacetylate histones NoRC negatively regulates rRNA expression Potential therapeutics for SARS	HDACs deacetylate histones HATs acetylate histones HATs acetylate histones RMTs methylate histone arginines UCH proteinases Ub-specific processing proteases Metalloprotease DUBs HCMV Early Events HCMV Late Events
Drugs
Diseases
GWAS
Interacting Genes		28 interacting genes: BRMS1 BRMS1L CIRSR CYTOR H2AC16 H2BC21 H3-4 H4C16 HBP1 HDAC1 HDAC2 HTT ID3 ING1 MXD1 NCOR1 NCOR2 PCBD1 RBBP4 RBBP7 RBP1 SAMSN1 SAP30BP SIN3A UHRF1 VHL YY1 ZNF395	5 interacting genes: BRD7 CRP GADD45A SAP30 TERF2IP
Entrez ID		8819	8332
HPRD ID		04540	09103
Ensembl ID		ENSG00000164105	ENSG00000276903
Uniprot IDs		O75446	A4FTV9 P0C0S8
PDB IDs		2KDP	4QYL 5KGF 6R0C 6RNY 6X59 6X5A 6XJD 7BG9 7E8D 7JO9 7JOA 7TAN 7U50 7U51 7U52 7U53 7UV9 8ATF 8AV6 8GUI 8GUJ 8GUK 8OFF 8QZM 8VOB 8VWS 8VWT 8VWU 8VWV 9DWF 9DWG 9DWH 9DWI 9DWJ 9DWK 9DWL 9DWM
Enriched GO Terms of Interacting Partners?		Sin3-type Complex Negative Regulation Of Stem Cell Population Maintenance Positive Regulation Of Stem Cell Population Maintenance Regulation Of Stem Cell Population Maintenance Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Histone Deacetylase Binding Histone Deacetylase Complex Negative Regulation Of RNA Metabolic Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Nucleoplasm Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Chromatin Organization Negative Regulation Of Nucleobase-containing Compound Metabolic Process Nucleus Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process NuRD Complex Negative Regulation Of Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Metabolic Process Negative Regulation Of Cell Migration Regulation Of Cell Fate Specification Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Cell Motility Negative Regulation Of Locomotion Negative Regulation Of Developmental Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Cell Fate Commitment Transcription Corepressor Activity Regulation Of Metabolic Process Negative Regulation Of Signal Transduction Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process ESC/E(Z) Complex Negative Regulation Of Cell Communication Negative Regulation Of Signaling Negative Regulation Of Androgen Receptor Signaling Pathway Heterochromatin Formation Rhythmic Process Transcription Repressor Complex	Regulation Of Reactive Oxygen Species Metabolic Process Positive Regulation Of Reactive Oxygen Species Metabolic Process Negative Regulation Of Protein Phosphorylation Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Phosphate Metabolic Process Negative Regulation Of Phosphorylation Negative Regulation Of Peptidyl-serine Phosphorylation Of STAT Protein Regulation Of Double-strand Break Repair Negative Regulation Of DNA Recombination At Telomere Negative Regulation Of Developmental Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Choline Binding Regulation Of Developmental Process Negative Regulation Of Peptidyl-serine Phosphorylation Transcription Corepressor Activity Histone H3K14ac Reader Activity Regulation Of Chromosome Organization Regulation Of DNA Repair Protection From Non-homologous End Joining At Telomere Shelterin Complex Negative Regulation Of Macromolecule Metabolic Process Complement Component C1q Complex Binding Positive Regulation Of DNA Metabolic Process Nuclear Telomere Cap Complex Virion Binding Negative Regulation Of Metabolic Process G-rich Strand Telomeric DNA Binding Regulation Of Multicellular Organismal Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Macrophage Derived Foam Cell Differentiation Negative Regulation Of DNA-templated Transcription Negative Regulation Of Cell Motility Negative Regulation Of Cell Migration Negative Regulation Of RNA Biosynthetic Process Protein Localization To Chromosome, Telomeric Region Telomere Capping Telomere Maintenance In Response To DNA Damage Low-density Lipoprotein Particle Binding Opsonization Regulation Of Metabolic Process Regulation Of DNA-templated Transcription Negative Regulation Of RNA Metabolic Process Regulation Of Protein Phosphorylation Negative Regulation Of Locomotion Regulation Of RNA Biosynthetic Process RSC-type Complex Positive Regulation Of Superoxide Anion Generation Regulation Of Phosphorylation Negative Regulation Of Lipid Storage
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