SAP30 and HBP1

Number of citations of the paper that reports this interaction (PMID 15235594)
21

Data Source:
HPRD (in vivo)

		SAP30	HBP1
Gene Name		Sin3A-associated protein, 30kDa	HMG-box transcription factor 1
Image
Gene Ontology Annotations	Cellular Component	Histone Deacetylase Complex Nucleoplasm	Nucleoplasm
	Molecular Function	DNA Binding Transcription Corepressor Activity Protein Binding Metal Ion Binding	DNA Binding RNA Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Organization Transcription, DNA-templated Regulation Of Transcription, DNA-templated Gene Expression Skeletal Muscle Cell Differentiation Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression, Epigenetic	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cell Cycle Arrest Wnt Signaling Pathway Positive Regulation Of Potassium Ion Transport
Pathways		NoRC negatively regulates rRNA expression Chromatin modifying enzymes Chromatin organization HDACs deacetylate histones Epigenetic regulation of gene expression Negative epigenetic regulation of rRNA expression
Drugs
Diseases
GWAS
Protein-Protein Interactions		27 interactors: ARID4A BRMS1 BRMS1L CIR1 HBP1 HDAC1 HDAC2 HIST1H2AL HIST2H2BE HIST3H3 HIST4H4 HTT ID3 ING1 LINC00152 MXD1 NCOR1 NCOR2 PCBD1 RBBP4 RBBP7 RBP1 SAMSN1 SAP30BP SIN3A YY1 ZNF395	15 interactors: ANKRD2 CD2AP CREBBP EP300 EWSR1 HDAC1 KIAA1279 RB1 RBL2 SAP30 SIN3A SMAD1 TCF4 TMEM37 ZNF212
Entrez ID		8819	26959
HPRD ID		04540	13634
Ensembl ID		ENSG00000164105	ENSG00000105856
Uniprot IDs		O75446	B4DJ36 O60381
PDB IDs		2KDP	2E6O 3QVE
Enriched GO Terms of Interacting Partners?		Chromosome Organization Negative Regulation Of Gene Expression Chromatin Organization Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Chromatin Modification Negative Regulation Of Biosynthetic Process Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression, Epigenetic Gene Expression Heterocycle Metabolic Process Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process RNA Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Organelle Organization Regulation Of Metabolic Process Histone Deacetylation Histone Modification Protein Deacetylation ATP-dependent Chromatin Remodeling Rhythmic Process Histone H3-K9 Modification Transcription From RNA Polymerase II Promoter Circadian Rhythm Chromatin Remodeling CENP-A Containing Nucleosome Assembly Histone Exchange DNA Replication-independent Nucleosome Assembly Homeostatic Process Nucleosome Assembly Cellular Metabolic Process Chromatin Assembly Establishment Of Sertoli Cell Barrier	Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Chromosome Organization Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Chromatin Organization Negative Regulation Of RNA Biosynthetic Process RNA Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Gene Expression Regulation Of RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Striated Muscle Tissue Development Chromatin Modification N-terminal Peptidyl-lysine Acetylation Positive Regulation Of Transcription From RNA Polymerase II Promoter Muscle Tissue Development Regulation Of Gene Expression Skeletal Muscle Tissue Development Regulation Of Nitrogen Compound Metabolic Process Skeletal Muscle Organ Development Positive Regulation Of Transcription, DNA-templated Skeletal Muscle Cell Differentiation Regulation Of Gene Expression, Epigenetic Nucleobase-containing Compound Metabolic Process Muscle Structure Development Regulation Of Cell Cycle Negative Regulation Of Cellular Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Gene Expression, Epigenetic Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process N-terminal Protein Amino Acid Acetylation Muscle Organ Development Organelle Organization Rhythmic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress
Tagcloud ?		affects chip deacetylation detecting differential dual encoded enzyme hdac herpes hsv htrp inhibit interact kmb luciferase lysine msin3a promote real regulator repressor reveal significance simplex synergistically transfer viral whose	alkaline anthraquinone ascorbic bark chemotherapeutic colorectal complementary emodin emodins gaining lef medicinal methylanthraquinone oncogenesis owing phytochemicals players repressor rescued roots scavenger snail sw480 sw620 tcf tcf7l2 trihydroxy vimentin wnt
Tagcloud (Difference) ?		affects chip deacetylation detecting differential dual encoded enzyme hdac herpes hsv htrp inhibit interact kmb luciferase lysine msin3a promote real regulator reveal significance simplex synergistically transfer viral whose	alkaline anthraquinone ascorbic bark chemotherapeutic colorectal complementary emodin emodins gaining lef medicinal methylanthraquinone oncogenesis owing phytochemicals players rescued roots scavenger snail sw480 sw620 tcf tcf7l2 trihydroxy vimentin wnt
Tagcloud (Intersection) ?		repressor