SAP30 and SAP30BP

Number of citations of the paper that reports this interaction (PubMedID 15496587)
0

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		SAP30	SAP30BP
Description		Sin3A associated protein 30	SAP30 binding protein
Image			No pdb structure
GO Annotations	Cellular Component	Histone Deacetylase Complex Nucleus Nucleoplasm Sin3-type Complex	Nucleus Nucleoplasm Intermediate Filament Cytoskeleton
	Molecular Function	DNA Binding Transcription Coregulator Activity Transcription Corepressor Activity Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Negative Regulation Of Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Skeletal Muscle Cell Differentiation Negative Regulation Of Stem Cell Population Maintenance Positive Regulation Of Stem Cell Population Maintenance	Regulation Of DNA-templated Transcription Response To Virus
Pathways		HDACs deacetylate histones NoRC negatively regulates rRNA expression Potential therapeutics for SARS	NoRC negatively regulates rRNA expression
Drugs
Diseases
GWAS			Rotator cuff tears ( 26350878)
Interacting Genes		28 interacting genes: BRMS1 BRMS1L CIRSR CYTOR H2AC16 H2BC21 H3-4 H4C16 HBP1 HDAC1 HDAC2 HTT ID3 ING1 MXD1 NCOR1 NCOR2 PCBD1 RBBP4 RBBP7 RBP1 SAMSN1 SAP30BP SIN3A UHRF1 VHL YY1 ZNF395	25 interacting genes: DHX8 FHL2 FHL3 FRA10AC1 GOLGA2 GSK3B MLX OGT PRKAR1B PUF60 RBM17 RBM39 RPS6KA6 SAP30 SNCA SUPT5H TFIP11 THAP1 THOC1 U2AF2 USP7 WDR77 WDR83 ZNF212 ZNF408
Entrez ID		8819	29115
HPRD ID		04540	17094
Ensembl ID		ENSG00000164105	ENSG00000161526
Uniprot IDs		O75446	Q9UHR5
PDB IDs		2KDP
Enriched GO Terms of Interacting Partners?		Sin3-type Complex Negative Regulation Of Stem Cell Population Maintenance Positive Regulation Of Stem Cell Population Maintenance Regulation Of Stem Cell Population Maintenance Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Histone Deacetylase Binding Histone Deacetylase Complex Negative Regulation Of RNA Metabolic Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Nucleoplasm Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Chromatin Organization Negative Regulation Of Nucleobase-containing Compound Metabolic Process Nucleus Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process NuRD Complex Negative Regulation Of Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Metabolic Process Negative Regulation Of Cell Migration Regulation Of Cell Fate Specification Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Cell Motility Negative Regulation Of Locomotion Negative Regulation Of Developmental Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Cell Fate Commitment Transcription Corepressor Activity Regulation Of Metabolic Process Negative Regulation Of Signal Transduction Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process ESC/E(Z) Complex Negative Regulation Of Cell Communication Negative Regulation Of Signaling Negative Regulation Of Androgen Receptor Signaling Pathway Heterochromatin Formation Rhythmic Process Transcription Repressor Complex	RNA Splicing MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing, Via Transesterification Reactions Nucleus MRNA Metabolic Process Nucleoplasm RNA Metabolic Process RNA Processing Spliceosomal Complex Regulation Of Nucleobase-containing Compound Metabolic Process TOR Signaling Nucleic Acid Metabolic Process Regulation Of RNA Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Protein Catabolic Process Macromolecule Metabolic Process Negative Regulation Of Protein-containing Complex Assembly Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of MRNA Processing Regulation Of Primary Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process TORC1 Signaling Nucleic Acid Binding Regulation Of RNA Splicing Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Calcineurin-NFAT Signaling Cascade Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Catabolic Process Regulation Of Autophagy Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Protein Kinase A Catalytic Subunit Binding Catalytic Step 2 Spliceosome Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Calcium-mediated Signaling Negative Regulation Of Macromolecule Metabolic Process Sin3-type Complex Negative Regulation Of Autophagy Identical Protein Binding Negative Regulation Of Signal Transduction Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of RNA Metabolic Process Regulation Of Gene Expression Negative Regulation Of Stem Cell Population Maintenance Alternative MRNA Splicing, Via Spliceosome
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