TANC1 and SHANK1

Number of citations of the paper that reports this interaction (PMID 15673434)
1

Data Source:
HPRD (in vitro)

		TANC1	SHANK1
Gene Name		tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1	SH3 and multiple ankyrin repeat domains 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Postsynaptic Density Cell Junction Dendrite Neuronal Cell Body Axon Terminus Postsynaptic Membrane	Intracellular Cytoplasm Plasma Membrane Ionotropic Glutamate Receptor Complex Membrane N-methyl-D-aspartate Selective Glutamate Receptor Complex Cell Junction Dendrite Neuron Projection Dendritic Spine Postsynaptic Membrane Excitatory Synapse Neuronal Postsynaptic Density
	Molecular Function		Protein Binding Protein C-terminus Binding SH3 Domain Binding GKAP/Homer Scaffold Activity Somatostatin Receptor Binding Protein Complex Binding Ionotropic Glutamate Receptor Binding Identical Protein Binding Ankyrin Repeat Binding Scaffold Protein Binding
	Biological Process	Myoblast Fusion Visual Learning Dendritic Spine Maintenance	Protein Complex Assembly Cytoskeletal Anchoring At Plasma Membrane Long-term Memory Associative Learning Adult Behavior Negative Regulation Of Actin Filament Bundle Assembly Social Behavior Protein Localization To Synapse Olfactory Behavior Habituation Neuromuscular Process Controlling Balance Determination Of Affect Righting Reflex Synapse Maturation Dendritic Spine Morphogenesis Positive Regulation Of Dendritic Spine Development Vocalization Behavior Regulation Of Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Activity Positive Regulation Of Excitatory Postsynaptic Membrane Potential
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: ACTB CAMK2A CASK DLG1 DLG4 DLGAP1 GRIA1 GRIN2B HOMER1 INA SHANK1 SPTAN1	17 interactors: ABCA1 ARHGEF7 BAI2 BAIAP2 DLG4 DLGAP1 DNM2 HOMER1 LPHN1 LPHN2 RPS6KA2 RPS6KA3 SHARPIN SPTAN1 SSTR2 STAT1 TANC1
Entrez ID		85461	50944
HPRD ID		18146	05413
Ensembl ID		ENSG00000115183	ENSG00000161681
Uniprot IDs		B9EK39 Q9C0D5	H9KV90 Q9Y566
PDB IDs
Enriched GO Terms of Interacting Partners?		Synaptic Transmission Protein Localization To Synapse Cell-cell Signaling Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Ion Transport Neuron Projection Morphogenesis Cell Morphogenesis Involved In Differentiation Axon Guidance Regulation Of Synaptic Plasticity Regulation Of Ion Transmembrane Transport Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Single-organism Behavior Positive Regulation Of Ion Transport Nucleotide Phosphorylation Neuron Development Axonogenesis Glutamate Receptor Signaling Pathway Axon Development Regulation Of Excitatory Postsynaptic Membrane Potential Receptor Localization To Synapse Cell Morphogenesis Regulation Of Postsynaptic Membrane Potential Behavior Chemotaxis Learning Or Memory Regulation Of Membrane Potential Neuron Differentiation Cell Development Cell Projection Organization Cognition Positive Regulation Of Calcium Ion Transport Regulation Of Synaptic Transmission Dendritic Spine Morphogenesis System Development Vocalization Behavior Membrane Depolarization Memory Dendritic Spine Development Neuromuscular Process Nervous System Development Learning Regulation Of Ion Transmembrane Transporter Activity Dendritic Spine Organization Regulation Of Transmembrane Transporter Activity Cell Differentiation Generation Of Neurons Multicellular Organismal Development Regulation Of Calcium Ion Import	Synaptic Transmission Neuron Projection Morphogenesis Cell Projection Organization Signaling Nervous System Development Cell Communication Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Cell Surface Receptor Signaling Pathway Axonogenesis Response To External Stimulus Anatomical Structure Development Cell-cell Signaling Axon Development Regulation Of Cellular Component Organization System Development Cell Morphogenesis Involved In Neuron Differentiation Neuron Development Cell Differentiation Signal Transduction Cell Morphogenesis Developmental Process Axon Guidance Neuron Differentiation Cell Morphogenesis Involved In Differentiation Response To Stimulus Multicellular Organismal Development Cell Development Apoptotic Process Cellular Response To Stimulus Programmed Cell Death Chemotaxis Generation Of Neurons Cell Death Death Protein Localization To Synapse Neurogenesis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Dendritic Spine Organization G-protein Coupled Receptor Signaling Pathway Anatomical Structure Morphogenesis Response To Organic Substance Cellular Response To Organic Substance Regulation Of Cell Morphogenesis Enzyme Linked Receptor Protein Signaling Pathway Response To Bacterium Neurotrophin TRK Receptor Signaling Pathway Response To Nutrient Neurotrophin Signaling Pathway
Tagcloud ?			akap6 atf7 atxn1 bmpr2 categorize deltan eef1a1 grip2 gtf2f1 interactors jbd jbds jnk1alpha1 jnk3 jnk3alpha1 jnks kcne4 myo9b nnat pias1 ptgds ptpn2 rabgap1 rusc2 sumo1 sypl1 tkt topbp1 znf668
Tagcloud (Difference) ?			akap6 atf7 atxn1 bmpr2 categorize deltan eef1a1 grip2 gtf2f1 interactors jbd jbds jnk1alpha1 jnk3 jnk3alpha1 jnks kcne4 myo9b nnat pias1 ptgds ptpn2 rabgap1 rusc2 sumo1 sypl1 tkt topbp1 znf668
Tagcloud (Intersection) ?