TANC1 and SPTAN1

Number of citations of the paper that reports this interaction (PMID 15673434)
1

Data Source:
HPRD (in vitro, in vivo)

		TANC1	SPTAN1
Gene Name		tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1	spectrin, alpha, non-erythrocytic 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Postsynaptic Density Cell Junction Dendrite Neuronal Cell Body Axon Terminus Postsynaptic Membrane	Cytosol Fascia Adherens Spectrin Microtubule Cytoskeleton Membrane Lateral Plasma Membrane Z Disc Vesicle Cuticular Plate Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome
	Molecular Function		Actin Binding Structural Constituent Of Cytoskeleton Calcium Ion Binding Protein Binding Calmodulin Binding Spectrin Binding Protein Heterodimerization Activity
	Biological Process	Myoblast Fusion Visual Learning Dendritic Spine Maintenance	Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Axon Guidance Actin Filament Capping
Pathways			Interaction between L1 and Ankyrins Apoptotic cleavage of cellular proteins Axon guidance Programmed Cell Death Apoptotic execution phase Nephrin interactions L1CAM interactions Caspase-mediated cleavage of cytoskeletal proteins NCAM signaling for neurite out-growth
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: ACTB CAMK2A CASK DLG1 DLG4 DLGAP1 GRIA1 GRIN2B HOMER1 INA SHANK1 SPTAN1	48 interactors: ABI1 ABL1 ACP1 ACTA1 ACTB ADD1 ANK1 CAPN1 CASP3 CASP7 CEP63 CTNNA1 DDX24 DES DISC1 EPB41 EPB41L2 EPB42 ERCC4 EVL EXOC1 FANCA FANCC GAP43 GRIA2 GRIN1 GRIN2A GRIN2B GRIN2D MAPK6 NEFL PIN4 PLEC PLEKHA5 PRKCB PTOV1 SHANK1 SHANK3 SLC9A2 SOS1 SPTB SPTBN1 SRC STAT1 SYN1 TANC1 TES TSSC4
Entrez ID		85461	6709
HPRD ID		18146	01684
Ensembl ID		ENSG00000115183	ENSG00000197694
Uniprot IDs		B9EK39 Q9C0D5	Q13813
PDB IDs			2FOT 3F31 3FB2
Enriched GO Terms of Interacting Partners?		Synaptic Transmission Protein Localization To Synapse Cell-cell Signaling Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Ion Transport Neuron Projection Morphogenesis Cell Morphogenesis Involved In Differentiation Axon Guidance Regulation Of Synaptic Plasticity Regulation Of Ion Transmembrane Transport Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Single-organism Behavior Positive Regulation Of Ion Transport Nucleotide Phosphorylation Neuron Development Axonogenesis Glutamate Receptor Signaling Pathway Axon Development Regulation Of Excitatory Postsynaptic Membrane Potential Receptor Localization To Synapse Cell Morphogenesis Regulation Of Postsynaptic Membrane Potential Behavior Chemotaxis Learning Or Memory Regulation Of Membrane Potential Neuron Differentiation Cell Development Cell Projection Organization Cognition Positive Regulation Of Calcium Ion Transport Regulation Of Synaptic Transmission Dendritic Spine Morphogenesis System Development Vocalization Behavior Membrane Depolarization Memory Dendritic Spine Development Neuromuscular Process Nervous System Development Learning Regulation Of Ion Transmembrane Transporter Activity Dendritic Spine Organization Regulation Of Transmembrane Transporter Activity Cell Differentiation Generation Of Neurons Multicellular Organismal Development Regulation Of Calcium Ion Import	Cell Morphogenesis Neuron Projection Morphogenesis Neuron Projection Development Cell Projection Organization Axon Development Cell Projection Morphogenesis Cell Development Cell Part Morphogenesis Cell Morphogenesis Involved In Differentiation Cell Morphogenesis Involved In Neuron Differentiation Cytoskeleton Organization Neuron Differentiation Neuron Development Axon Guidance Cell Differentiation Neurogenesis Anatomical Structure Morphogenesis Generation Of Neurons Axonogenesis Neuromuscular Process Movement Of Cell Or Subcellular Component Ionotropic Glutamate Receptor Signaling Pathway Chemotaxis Organelle Organization System Development Synaptic Transmission, Glutamatergic Response To External Stimulus Anatomical Structure Development Homeostatic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Cellular Component Organization Locomotion Glutamate Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Nervous System Development Membrane Depolarization Synaptic Transmission Neuron-neuron Synaptic Transmission Cellular Component Assembly Startle Response Actin Filament-based Process Developmental Process Regulation Of Excitatory Postsynaptic Membrane Potential Learning Multicellular Organismal Development Regulation Of Postsynaptic Membrane Potential Signaling Response To Wounding Cell Communication Cellular Response To Stimulus
Tagcloud ?			adenocarcinomas atxn2 biology consistently couple deregulation dhx9 driver exome hundreds kras mutations myof never overlap preferentially ptpn13 recurrent respective rps6kb2 seq sequenced smokers somatic sp1 stratification targetable ten thousands
Tagcloud (Difference) ?			adenocarcinomas atxn2 biology consistently couple deregulation dhx9 driver exome hundreds kras mutations myof never overlap preferentially ptpn13 recurrent respective rps6kb2 seq sequenced smokers somatic sp1 stratification targetable ten thousands
Tagcloud (Intersection) ?